Clinical trials: CPPD - Calcium Pyrophosphate Deposition Disease, open to volunteers
CPPD - Calcium Pyrophosphate Deposition Disease
Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment
The goal of this clinical trial is to learn if colchicine reduces levels of proteins indicating inflammation in the blood in individuals with calcium pyrophosphate deposition (CPPD) disease.
- Trial name
- CRYSTALLIZE (NCT06855433)
- Testing
- Colchicine Pill
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Brigham and Women's Hospital
Calcium Pyrophosphate Deposition Disease, Rheumatic Diseases
Calcium Pyrophosphate Deposition (CPPD) Disease
The goal of this clinical trial is to describe the transcriptomic and metabolomic profile of patients with chronic Calcium Pyrophosphate Deposition (CPPD) compared to those with acute CPPD.
- Trial name
- PYC-OMIC (NCT07005804)
- Testing
- transcriptomic and metabolomic analysis
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Lille Catholic University
Calcium Pyrophosphate Deposition Disease, Chondrocalcinosis
Baricitinib in CPPD - the BAPTIST Study
The aim of this clinical trial is to determine if baricitinib is effective in treating calcium pyrophosphate deposition disease (CPPD) in adults. The primary objective is to assess its impact on joint inflammation.
- Trial name
- BAPTIST (NCT06768294)
- Testing
- Baricitinib 4 MG Oral Tablet, Methylprednisolone (Corticosteroid), Colchicine 1 MG Oral Tablet
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Calcium Pyrophosphate Deposition Disease
Tocilizumab in Chronic Inflammatory CPPD Disease
The aim of this clinical trial is to determine the efficacy of tocilizumab (an IL-6 inhibitor) in treatment-refractory chronic inflammatory forms of CPPD.
- Trial name
- TociCCAre (NCT07254637)
- Testing
- Tocilizumab
- Where
- 12 sites in France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gitelman Syndrome, CPPD - Calcium Pyrophosphate Deposition Disease
The Osteoarticular Manifestations in Patients With Gitelman Syndrome
Patients with clinically and genetically confirmed Gitelman Syndrome are screened for CPPD, and the clinical and radiographic manifestations are collected and analyzed.
- Trial name
- CPPD and more (NCT06922370)
- Testing
- conventional radiograph or computed tomography
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
CPPD - Calcium Pyrophosphate Deposition Disease, Gout
The Orienting Study
This study at IRCCS Galeazzi - Sant'Ambrogio Hospital involves patients with gout, CPPD, and osteoarthritis as a control group. Patients will receive routine care with regular clinical, laboratory, and imaging assessments every…
- Trial name
- ORIENTING (NCT07504146)
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio