Clinical trials: CRC
Breast Cancer, Colorectal Cancer
KanSurvive: Testing a Model for Improving Cancer Survivorship Care in Rural Practice
Approximately, 20 rural primary care practices to participate in a delayed intervention-controlled trial. Phase I: Formal and structured work flow evaluations to better identify specific gaps in processes of care while assessing…
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- KANSURVIVE (NCT04763824)
- Testing
- KanSurvive ECHO and Practice Facilitation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Colorectal Cancer
Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
This is a prospective randomized study to evaluate the difference in the rate of surgical site infection between the patients who used Sodium Picosulfate solution(PicosolutionⓇ) and tablet Oral Sulphate Solution(ORA·FANGⓇ) for…
- Trial name
- NCT04593446
- Testing
- Oral Sulfate Tablet(ORA·FANGⓇ), Sodium Picosulfate Solution(PicosolutionⓇ)
- Where
- South Korea
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Colorectal Cancer
Colonoscope Insertion Trial Protocol
This research study is about determining how well a Technically Improved Colonoscope from Olympus works in helping the doctor in guiding the scope through the large bowel or colon.
- Trial name
- NCT01324882
- Testing
- Colonoscopy with Olympus Technically Improved Colonoscope, Control with standard colonoscope Olympus CF-H180
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- UConn Health
Colorectal Cancer
Shared Decision-making and Colorectal Cancer Screening
Conduct a feasibility pilot RCT of a newly developed colorectal cancer screening (CRC) decision aid (DA) including 66 LHL adults 76-85 years recruited from community health centers.
- Trial name
- NCT04748380
- Testing
- CRC decision aid pamphlet, Home Safety Pamphlet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
GENE EXPRESSION, Colorectal Cancer
Scottish Vitamin D Intervention Study
AIMS To identify the underlying mechanism by which Vitamin D reduces colorectal cancer risk. OBJECTIVES To demonstrate the effects of vitamin D supplementation on serum vitamin D levels.
- Trial name
- (SCoViDS) (NCT04868227)
- Testing
- FULTIUM D3 VITAMIN D3
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Lung Cancer, Colorectal Cancer
PD-L2 Targeting Nanobody Radiotracer for PET Imaging of Solid Tumor
The objective of this study is to construct a noninvasive approach using 68Ga- Mirc415 PET/CT to detect the PD-L2 expression of tumor lesion in patients with colorectal cancer, lung cancer and other solid tumor to identify…
- Trial name
- NCT05803746
- Testing
- 18F-FDG
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Colorectal Cancer
Implication of Genetic Variations in Long Intergenic Non-coding RNA 00511 (LINC00511) in Colorectal Cancer
As, there is a lack of information about the association between LINC00511 SNP(s) variants and CRC susceptibility, so this study was undertaken to address whether these SNPs would increase CRC risk or could predict its prognosis.
- Trial name
- NCT06534242
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Colorectal Cancer, Colorectal Neoplasm
A Stool DNA Test for Detection of Advanced Colorectal Neoplasia in Asymptomatic Chinese Community Population
to determine screening value of stool-based SDC2 DNA methylation test for advanced colorectal neoplasia in the asymptomatic Chinese community population.
- Conditions
- Colorectal Cancer, Colorectal Neoplasm, Advanced Adenoma, Adenoma
- Trial name
- NCT04786704
- Testing
- Stool-based SDC2 DNA methylation test, quantitative Fecal immunochemical test
- Where
- China
- Volunteers
- 12,106 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer, Colorectal Adenoma
Protein Signature Based Screening of Colorectal Adenomas and Cancer
Colorectal cancer is a common cancer, that in general develops over a long time period (approximately 10-15 years) from precancerous polyps. The disease is in many cases asymptomatic.
- Trial name
- NCT07881549
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Region Skane
Colorectal Cancer
Personalized Screening Plans to Increase Colorectal Cancer Screening in Healthy Participants
RATIONALE: Developing a personalized screening plan may be more effective than usual care in increasing the number of healthy participants who regularly undergo screening for colorectal cancer.
- Trial name
- NCT00617071
- Testing
- medical chart review, survey administration, fecal occult blood test
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Colorectal Cancer
Chemoprevention of Colorectal Cancer: the Role of Non-digestible Carbohydrates
Colorectal cancer is a common disease worldwide. It is now thought that colorectal cancer cells arise from stem cells where the genetic material regulating growth and division of the stem cell has become defective.
- Trial name
- NCT01214681
- Testing
- Maltodextrin and Amioca starch, Hi-maize 260, Polydextrose
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Non-small Cell Lung Cancer, Esophageal Cancer
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery.
- Conditions
- Non-small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT02838836
- Testing
- Study sample collection
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Colorectal Neoplasms, Colonoscopy
AI-empowered Nudge to Improve Colonoscopy Uptake (AINC)
Colorectal cancer (CRC) ranks third in both incidence and mortality among all malignant tumors in China. Studies have shown that early screening can significantly reduce its incidence and mortality.
- Trial name
- NCT07612436
- Testing
- AI-empowered nudge (AINC) strategy, Usual Care
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Fudan University
Gastrointestinal Diseases, Colorectal Cancer
Optimizing the Preparation Regime Prior to Colonoscopy Procedure With Pure-Vu System
The primary objective of this multicenter, prospective, randomized study is to evaluate the performance of Pure-Vu System in cleansing patients' colon who are indicated for a colonoscopy procedure using one of two different…
- Trial name
- NCT03493009
- Testing
- Pure-Vu System
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Type 1 Diabetes Mellitus
Study Assessing an Insulin Pump-controlling Algorithm to Minimize Hypo and Hyper in Type 1 During CRC Setting
Feasibility study assessing the ability of an insulin pump-controlling algorithm to minimize hypoglycemia and hyperglycemia in patients with type 1 diabetes in a clinical research setting.
- Trial name
- NCT01638299
- Testing
- Hypo-Hyper Minimizer (HHM) System
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Animas Corporation
Colorectal Cancer
Attitudes Towards Prophylactic Colectomy in Hereditary Non-polyposis Colorectal Cancer (HNPCC) Patients
The purpose of this study is to learn more about individual's with a family history of colon cancer and the process by which they may decide to undergo or not undergo prophylactic colectomy.
- Trial name
- NCT00582452
- Testing
- Telephone survey
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms, Colonic Polyps
Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study
We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.
- Conditions
- Colorectal Neoplasms, Colonic Polyps, Colorectal Cancer
- Trial name
- NBI (NCT01310699)
- Testing
- Olympus Colonoscope CFHQ190AL
- Where
- 3 sites in United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colorectal Cancer
Reducing Colorectal Cancer Death Through Mailed Outreach Screening
The main study aim is to develop, implement and disseminate a pilot population-based mailed FIT outreach screening program in the Philadelphia VA Medical Center that does not rely on having an office visit, by conducting a…
- Trial name
- NCT02584998
- Testing
- Mailed-FIT, Screening invitation-reminder
- Where
- United States
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colo-rectal Cancer, Colon Cancer
Ellagic Acid, Urolithin and Colonic Microbial Communities Affected by Walnut Consumption
Briefly, this is a 28-day dietary intervention study participants will be asked to eat 2 ounces (52 grams) of walnuts every day for 3 weeks, and at the end of the study period they will come in for a colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Cancer, Diet Habit
- Trial name
- NCT04066816
- Testing
- Walnuts
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- UConn Health