Clinical trials: CRC Screening, open to volunteers
Colorectal Cancer Screening
Pilot Testing of a Colorectal Cancer Education Program
The primary objective of this study is to assess the feasibility, acceptability, and preliminary efficacy of a culturally and linguistically targeted, colorectal cancer (CRC) education program to improve CRC screening completion.
- Trial name
- NCT07361614
- Testing
- Educational Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colorectal Neoplasms, Early Detection of Cancer
Impact of SMS Messaging on Participation in Colorectal Cancer Screening
Colorectal cancer is a leading cause of mortality in Catalonia. Although early detection programs using the fecal immunochemical test (FIT) are effective in reducing both incidence and mortality, their success relies on high…
- Trial name
- NCT07628998
- Testing
- Text Messaging, Standard invitation and postal reminder letters
- Where
- Spain
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Colonoscopy (Procedure)
Use of GI Genius™ XR Software in Virtual Reality Headset During Routine Colonoscopy
This pilot study will evaluate the usability and safety of software GI Genius™ XR in the Apple Vision Pro™ virtual reality headset when used in conjunction with the GI Genius™ system during routine screening and surveillance…
- Trial name
- NCT07220174
- Testing
- software GI Genius™ XR on headset
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmo Artificial Intelligence-AI Ltd
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Colorectal Cancer Screening
Optimizing Participation In Colorectal Cancer Screening By Direct Invitation Of Non Responders By General Practitionners
The goal of this randomized trial is to assess the effectiveness of a targeted telephone reminder strategy, implemented by the patient's general practitioner, in enhancing participation in colorectal cancer screening among…
- Trial name
- OPTIDEC COLO (NCT07639554)
- Testing
- Intervention
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- MSPU des 3 Provinces
Screening for Colon Cancer, Blood Samples
Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection
The objective of this low-risk interventional study is to evaluate whether the PreveCol® test has sufficient efficiency to be considered as a second-line method for the detection of both colorectal cancer and advanced adenomas…
- Conditions
- Screening for Colon Cancer, Blood Samples, Survey and Questionnaire, Colorectal Carcinoma
- Trial name
- MS-Prevecol (NCT06703632)
- Testing
- blood sampling, Survey using a questionnaire.
- Where
- 2 sites in Portugal, Spain
- Volunteers
- 4,538 people, healthy volunteers welcome
- Sponsor
- ADVANCED MARKER DISCOVERY S.L.
Colorectal Carcinoma
Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
Although implementation intentions (I2)-based tools enhance colorectal cancer (CRC) screening uptake, prior studies have not tested their implementation into routine primary care delivery.
- Trial name
- (PB-iCRC) (NCT06682650)
- Testing
- NPT-PLA, Usual Quality Improvement
- Where
- United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Colorectal Cancer Screening, Hepatitis C Virus
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
- Trial name
- MATCHES (NCT06745895)
- Testing
- MATCHES
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer Early Detection
Efficacy and Tolerability of a Simethicone-containing Evacuating Solution for Colorectal Cancer Screening Colonoscopy
Study to evaluate the efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy.
- Trial name
- CLEAN+ (NCT07696793)
- Testing
- Clensia®, Citrafleet®
- Where
- Spain
- Volunteers
- 818 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Colorectal Cancer, Colorectal Neoplasms
Early Detection of Advanced Adenomas and Colorectal Cancer
This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
- Trial name
- AACRC (NCT06342440)
- Testing
- DENEB
- Where
- 6 sites in United States, China and 3 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Cancer
Mailed FIT-Based Outreach Interventions
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for…
- Trial name
- NCT07852793
- Testing
- SMS Reminders, SMS reminders + mailed reminder, SMS reminders + mailed reminder + patient navigation
- Where
- 5 sites in Singapore
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Colorectal Cancer
A Community Population Screening Cohort Study Based on Polygene Methylation Detection for Colorectal Cancer in Yangzhou
This is a cross-sectional cohort study based on community population jointly developed by Northern Jiangsu People's Hospital and Shanghai Kunyuan Biological Technology Co., LTD.
- Trial name
- NCT05336539
- Where
- 2 sites in China
- Volunteers
- 80,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.
Brain Cancer, Breast Cancer
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types.
- Conditions
- Brain Cancer, Breast Cancer, Bladder Cancer, Cervical Cancer
- Trial name
- CAMPERR (NCT05366881)
- Where
- 17 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Adela, Inc
Artificial Intelligence, Colonic Adenoma
Artificial Intelligence-Assisted Colonoscopy in Colorectal Cancer Screening in a General Hospital
Cancer can develop in the colon, or large bowel. Examination of the colon with a tube fitted with a camera is called a colonoscopy. Colonoscopy allows detection of small growths in the colon, called "polyps".
- Conditions
- Artificial Intelligence, Colonic Adenoma, Colonic Neoplasms, Colonic Polyp
- Trial name
- Delta-AI (NCT06792292)
- Testing
- conventional colonoscopy procedure, artificial intelligence-assisted colonoscopy procedure
- Where
- Belgium
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Chirec
Lifestyle Alteration, Tobacco
Targeting Lifestyle to Improve Colorectal Cancer Screening
The goal of this study is to learn whether receiving personalized, digital lifestyle advice during colorectal cancer screening leeds to changes in lifestyle over a two-year follow-up period.
- Conditions
- Lifestyle Alteration, Tobacco, Diet Modification, Physical Activity
- Trial name
- KoloPrev (NCT07135115)
- Testing
- Digikost report baseline only, Digikost report intensive with individual counselling and webinars, Digikost report intensive
- Where
- Norway
- Volunteers
- 16,000 people
- Sponsor
- Norwegian Institute of Public Health
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Cancer
Microbiome-based Diagnostic Tool for the Screening of Colorectal Cancer (GUILTI)
Colorectal cancer (CRC) is one of the most common cancer and cause of cancer death worldwide. Population-based screening programs for average risk populations have proven effective in reducing both incidence and mortality of CRC…
- Trial name
- GUILTI (NCT06738173)
- Testing
- Gut microbiome testing
- Where
- Italy
- Volunteers
- 1,202 people
- Sponsor
- Catholic University of the Sacred Heart
Colorectal Cancer
Rural Indiana Screening for Colorectal Cancer
The goal of this implementation study is to support an evidence-based intervention to the improve colorectal cancer (CRC) screening and diagnostic colonoscopy rates in rural Indiana.
- Trial name
- RISCC (NCT06133439)
- Testing
- Colorectal Screen rates with implementation of evidence-based intervention
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastric Cancer, Colorectal Cancer
Evaluation of Fecal Multi-target Biomarkers in the Screening of Digestive Tract Cancers
This study is a multi-center, observational study. Participants scheduled for gastroscopy and colonoscopy will undergo an epidemiological assessment and provide a stool sample prior to endoscopy for qualitative Fecal…
- Trial name
- NCT07600125
- Testing
- Qualitative Fecal Immunochemical Test (FIT), quantitative (FIT), and testing for new biomarkers
- Where
- 13 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Colonoscopy, Screening Colonscopy
What Influence Re-participation in the Danish Colorectal Screening Program.
This prospective observational study investigates how participants experience screening colonoscopy within the Danish colorectal cancer screening program and how these experiences relate to clinical findings, procedural factors…
- Conditions
- Colonoscopy, Screening Colonscopy, Pain
- Trial name
- NCT07353632
- Where
- 8 sites in Denmark
- Volunteers
- 8,000 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark