Clinical trials: CRP
Chronic Kidney Diseases, Chronic Kidney Insufficiency
A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP
This study will evaluate the safety, tolerability, pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 (also known as pacibekitug) in participants with chronic kidney disease…
- Conditions
- Chronic Kidney Diseases, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency
- Trial name
- TRANQUILITY (NCT06362759)
- Testing
- TOUR006 - 50 MG, TOUR006 - 25 MG, TOUR006 - 15 MG
- Where
- 38 sites in United States
- Volunteers
- 143 people
- Sponsor
- Tourmaline Bio, Inc., a Novartis Company
Acute Hydrocarbon Toxicity
Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals
Hydrocarbons are a primary energy source in modern society. They are present in many common household and occupational products, including motor fuels, paint thinners, cleaning agents, lotions, and industrial solvents.
- Trial name
- NCT06151301
- Testing
- serum procalcitonin, C-reactive protein
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Cesarean Delivery Affecting Newborn, Anesthesia
Hs-CRP and NLR as Markers of Perioperative Stress
The stress response to surgery is a result of tissue injury with local and systemic inflammation that contributes to the postoperative outcome.
- Conditions
- Cesarean Delivery Affecting Newborn, Anesthesia, Inflammatory Response
- Trial name
- NCT03594695
- Testing
- HSCRP and NLR
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ufuk University
Major Depressive Disorder
Lipopolysaccharide (LPS) Challenge in Depression
LPS Challenge in Individuals with Major Depressive Disorder
- Trial name
- NCT03142919
- Testing
- Lipopolysaccharide
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Acute Kidney Injury, Cardiac Surgery
Prediction of Acute Kidney Injury After Cardiac Surgery With Cardiopulmonary Bypass
Acute kidney injury (AKI) is a common and serious complication following cardiac surgery performed under cardiopulmonary bypass and is associated with increased morbidity, mortality, and prolonged hospital stay.
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Cardiopulmonary Bypass Surgery, Cardiac Surgery Associated - Acute Kidney Injury
- Trial name
- AKI-CPB (NCT07343830)
- Where
- Turkey (Türkiye)
- Volunteers
- 455 people
- Sponsor
- Ataturk University
COVID-19 Infection, Thyroid Function Tests
Thyroid Function Tests and Status of Thyroid Autoantibodies in Covid-19 Patients
COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation through cytokines in various organs of the body, especially the lungs.
- Conditions
- COVID-19 Infection, Thyroid Function Tests, Inflammation; Thyroid, Inflammatory Markers
- Trial name
- NCT04659200
- Testing
- Venous blood was collected for biochemistry testing.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Autoimmune, Lupus Erythematosus, Systemic
Effect of Green Tea on Treatment of Lupus
This randomized double blind clinical trial performed on 68 patients (32 in intervention and 36 in control group) diagnosed with SLE.
- Trial name
- NCT02875691
- Testing
- green tea extract
- Where
- Iran
- Volunteers
- 68 people
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Rheumatoid Arthritis
A Study Comparing CRx-102 Plus Disease-modifying Anti-rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in RA
This study was a Multicenter, Randomized, Blinded Study Comparing the Effect of CRx-102 Plus DMARD Therapy to that of Placebo Plus DMARD Therapy on Serum C Reactive Protein (CRP) and Cytokines in Subjects with Rheumatoid…
- Trial name
- NCT00747214
- Testing
- CRx-102, DMARD Therapy
- Volunteers
- 59 people
- Sponsor
- Zalicus
Acute Aortic Dissection, Surgery (Cardiac)
Immune-Inflammatory Markers in Aortic Dissection
Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for…
- Conditions
- Acute Aortic Dissection, Surgery (Cardiac), Systemic Immune-inflammation Index, Postoperative Death
- Trial name
- NCT07683260
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Bursa City Hospital
Colorectal Surgery, Enhanced Recovery
CRP Point-of-care Testing Trajectory, a Predictive Factor for Anastomotic Leak in Elective Colorectal Surgery
In colorectal surgery, one of the most feared complications is anastomotic leak (AL). To limit the consequences of AL, it must be diagnosed as early as possible, before it becomes symptomatic.
- Conditions
- Colorectal Surgery, Enhanced Recovery, CRP Point-of-care Testing Trajectory, Post-operative Complication
- Trial name
- CRP (NCT07464600)
- Testing
- blood sample, Blood taken from a fingertip, Abdomino-pelvic CT scan
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Juvenile Idiopathic Arthritis
Pharmacokinetics, Efficacy and Safety of Olokizumab In Patients With Juvenile Idiopathic Arthritis
The primary objective of this study is to evaluate the pharmacokinetics (PK) of olokizumab (OKZ) in patients with polyarticular juvenile idiopathic arthritis aged >2 and <18 years in two doses (64 mg or 48 mg every 4 weeks)…
- Trial name
- NCT07517575
- Testing
- OKZ q4w
- Where
- 14 sites in Russia
- Volunteers
- 71 people
- Sponsor
- R-Pharm International, LLC
Intensive Care
Effects of Neutrophil/Lymphocyte, Platelet/Lymphocyte, CRP/Albumin and Lactate on Mortality in Trauma Patients Admitted to Intensive Care
Intensive care units are medical units where patients are closely monitored 24 hours a day due to critical health problems that threaten their lives and where rapid interventions are made when necessary.
- Trial name
- NCT06667310
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Harran University
Coronary Disease
Vitamin D Deficiency in Coronary Artery Disease
Large population cross sectional study, was conducted between 2018-2020 by attendance of 4526 patients in shiraz, Iran. Patients were undergone selective coronary angiography from radial artery approach by an expert…
- Trial name
- NCT04651101
- Testing
- coronary angiography
- Where
- Iran
- Volunteers
- 4,526 people
- Sponsor
- Shiraz University of Medical Sciences
Sepsis, Morality
CRP Versus PCT as Bio-markers for Sepsis and in Guiding Antibiotics in Critically Ill Patients
Sepsis is a life threatening organ dysfunction caused by infection. Severe sepsis is expected to rise due to resistance to antibiotics.
- Trial name
- PCTCRP (NCT04049565)
- Testing
- Procalcitonin biomarker and CRP biomarker
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes
Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases
Type 2 diabetes is common in ethnic and, minority groups in developing and developed countries such as Africans, African Americans, Asians, Native Americans, Hispano-Latinos and Alaskan indians.
- Conditions
- Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes, Effects of Green Tea and FPP on C-reactive Proteins, Effects of Green Tea and FPP of Lipid Profiles in Diabetes
- Trial name
- NCT01248143
- Testing
- Green tea, FPP
- Where
- 3 sites in United States, Austria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Acute Heart Failure
Effect of Short-Term Prednisone Therapy on C-Reactive Protein Change in Emergency Department Patients With Acute Heart Failure and Elevated Inflammatory Markers ( CORTAHF )
Acute heart failure (AHF) is a common discharge diagnosis in the emergency department (ED), associated with 1-month mortality of 6%, and a 30% risk rate of 1-month rehospitalisation.
- Trial name
- CORTAHF (NCT05668676)
- Testing
- Prednisone arm, Usual care
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Pomegranate Improve Biological Recovery Kinetics in Elite Weightlifter
From the recent scientific literature in the field of biological response to physical exercise, a significant increase in muscle damage, soreness and inflammation were registered immediately and even 48 after resistance exercise.
- Trial name
- NCT02697903
- Testing
- Natural Pomegranate Juice
- Where
- Tunisia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Treatment Resistant Depression (TRD), Inflammation
TACS on High-inflammatory and Refractory Depression
This study is a randomized controlled trial with a duration of 12 weeks (4 weeks of intervention + 8 weeks of follow-up). The participants are patients with treatment-resistant depression (TRD) and high inflammatory activity…
- Trial name
- NCT06812923
- Testing
- transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Anding Hospital
Biomarkers
DIGIPREDICT-Physio-DE
The study aims to investigate short-term physiological and biochemical inflammatory and cardiocirculatory biomarker kinetics in heart failure patients, using the DIGIPREDICT Physiopatch device - an investigational device that…
- Trial name
- NCT05886569
- Testing
- DIGIPREDICT Physiopatech
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Febrile Illness Acute, Biomarkers
Clinical Aspects, Management and Surveillance of Febrile Illnesses in DRC
The epidemiology and outcome of febrile illnesses in the Democratic Republic of Congo (DRC) is poorly documented. The FIKI² study, a prospective observational study of community-acquired febrile illnesses coordinated by ITM and…
- Conditions
- Febrile Illness Acute, Biomarkers, Surveillance
- Trial name
- FI-CARE (NCT07345286)
- Where
- Democratic Republic of the Congo
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium