Clinical trials: CRPS, open to volunteers
Stellate Ganglion Block
Stellate Ganglion Block in Complex Regional Pain Syndrome
The aim was to investigate the effect of Stellate Ganglion Blockade, which will be applied in addition to conventional physical therapy, on pain and functionality in patients with poststroke complex regional pain syndrome.
- Trial name
- NCT07129811
- Testing
- Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara City Hospital Bilkent
Complex Regional Pain Syndromes, CRPS (Complex Regional Pain Syndromes)
Long-term Pain Modulation by Intravenous Esketamine in CRPS
Intravenous administration of esketamine is an effective recognized therapeutic option in refractory pain in CRPS, which sometimes in at least a part of the patients has a prolonged therapeutic effect.
- Trial name
- KetCRPS-2 (NCT05212571)
- Testing
- S-ketamine infusion inpatient setting, S-ketamine infusion outpatient setting
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Erasmus Medical Center
Wrist Fracture, Complex Regional Pain Syndrome
How the Brain and Body Recover After a Wrist Fracture
What is the problem? A wrist fracture is a common injury, affecting about 100,000 people in the UK each year. While most people recover well, a significant minority, between 10% and 20%, develop persistent pain and disability…
- Trial name
- PERCIPIENT (NCT07777081)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Complex Regional Pain Syndrome (CRPS)
Validity and Reliability of the Turkish Version of the Revised Bath CRPS Body Perception Disturbance Scale
This study aims to perform the cross-cultural adaptation of the Revised Bath Complex Regional Pain Syndrome Body Perception Disturbance Scale (r-B-CRPS-BPDS) into Turkish and to evaluate the validity and reliability of the…
- Trial name
- NCT07858812
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Izmir Democracy University
Pain Syndrome, Fibromyalgia
Neuro-modulation of Central Pain Pathways in Non Inflammatory Musculoskeletal Pain Syndrome
The aim of this clinical trial is to see if transcranial electrical stimulation (tES) can help reduce pain and improve quality of life in children and adolescents (ages 10-21, both sexes) with juvenile fibromyalgia or other…
- Conditions
- Pain Syndrome, Fibromyalgia, CRPS (Complex Regional Pain Syndromes), Neuromodulation
- Trial name
- NMJFP protocol (NCT07785362)
- Testing
- Neuro-modulation of central pain pathways in non inflammatory musculoskeletal pain syndrome (NMJFP)
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Istituto Giannina Gaslini
Complex Regional Pain Syndrome
Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome
The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS).
- Trial name
- LDN-CRPS (NCT02502162)
- Testing
- LDN
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
CRPS (Complex Regional Pain Syndromes), Radiculopathy
Intermittent Dosing of Dorsal Root Ganglion Stimulation as an Alternate Paradigm to Continuous Low-Frequency Therapy
This study seeks to evaluate the use of intermittent dosing as an alternative paradigm for patients with DRG stimulation in place for at least 1 year and minimum 50% pain relief in the targeted area.
- Conditions
- CRPS (Complex Regional Pain Syndromes), Radiculopathy, Peripheral Neuropathy
- Trial name
- NCT04909138
- Testing
- DRG stimulation 20 Hz 30/90, DRG stimulation 5 Hz 30/90
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush University Medical Center
Complex Regional Pain Syndrome I (CRPS I)
CRPS-RISE Outcomes Registry
The goal of this observational study is to learn about how well neridronate keeps working in the months after treatment. For 12 or up to 24 months while the registry is open participants will answer online survey questions about…
- Trial name
- NCT07811362
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Ambros Therapeutics, Inc.
Complex Regional Pain Syndromes
Role of the Gut Microbiome in Complex Regional Pain Syndrome
The objective of this prospective, observational study is to determine the association between the composition of the gut microbiota and the severity and persistence of Complex Regional Pain Syndrome symptoms (Study A).
- Trial name
- NCT03612193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Complex Regional Pain Syndrome (CRPS)
Clinical and Cerebral Changes Following Multifaceted Rehabilitation of Complex Regional Pain Syndrome
This study investigates the clinical effects of an individually tailored rehabilitation program for patients with Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT02753335
- Testing
- Individualized CRPS Rehabilitation
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- University Hospital of North Norway
Complex Regional Pain Syndromes, Distal Radius Fractures
Prednisone for CRPS in Distal Radius Fracture
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system.
- Trial name
- NCT06453447
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Pain Syndromes, CRPS
Neuro-Pain Provides a Dynamic and Interactive Register for the Invasvive Neuromodulatory Therapies for Different Chronic Pain Syndromes. Patients Living in Belgium and Suffering From Persistent Spinal Pain Syndromes Type 2 as Well as Suffering From Complex Regional Pain Syndromes Are Included.
Patients suffereing from chronic pain due to persistent spinal pain syndromes or complex regional pain syndromes and living in Belgium will be included in this register once they are being considered for a treatment with invasive…
- Trial name
- NCT06835868
- Testing
- Spinal cord stimulation
- Where
- Belgium
- Volunteers
- 7,000 people
- Sponsor
- University Hospital, Antwerp
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
CRPS (Complex Regional Pain Syndromes), CRPS (Complex Regional Pain Syndrome) Type I
Perineural Incobotulinumtoxin-A for Complex Regional Pain Syndrome - An Open-label Feasibility Study
Complex Regional Pain Syndrome (CRPS) is a chronic pain condition characterized by severe regional pain, sensory disturbances, and functional impairment.
- Conditions
- CRPS (Complex Regional Pain Syndromes), CRPS (Complex Regional Pain Syndrome) Type I, CRPS Type II
- Trial name
- PINCom (NCT07473635)
- Testing
- Perineural Incobotulinumtoxin-A 200 U
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Bo Biering-Soerensen
Chronic Pain, Musculoskeletal Pain
Empowered Relief for Caregivers
This study is testing a new program called Empowered Relief for Caregivers (ER-CY), designed to support caregivers of children and teens who live with chronic pain. ER-CY is a single two-hour class delivered online.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Fibromyalgia, Neuropathic Pain
- Trial name
- ER-CY (NCT07636980)
- Testing
- Empowered Relief for Caregivers (ER-CY)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Complex Regional Pain Syndromes
Closed Loop Spinal Cord Stimulation for Complex Regional Pain Syndrome
The primary purpose of this study is to determine the differences in response to treatment of complex regional pain syndrome with a closed-loop spinal cord stimulator if applied in the early phases (acute or subacute) versus the…
- Trial name
- NCT06421350
- Testing
- Spinal Cord Stimulation Device
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Scripps Health
Complex Regional Pain Syndrome, Chronic Pain
Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a rare and often debilitating chronic pain condition whereby individuals may experience extreme sensitivity, discoloration, and swelling of the affected area -- along with numerous other…
- Conditions
- Complex Regional Pain Syndrome, Chronic Pain, Causalgia, Complex Regional Pain Syndrome Type I
- Trial name
- LDN-CRPS (NCT06306157)
- Testing
- Low dose naltrexone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Hospital for Special Surgery, New York
Chronic Pain, Complex Regional Pain Syndromes
Dance-therapy and Chronic Pain
Pain, when it becomes chronic, can be a threat to patients and it is very common to observe a fear of pain and a fear of movement (kinesiophobia).
- Conditions
- Chronic Pain, Complex Regional Pain Syndromes, Tension-Type Headache
- Trial name
- ALGODANCE (NCT05689944)
- Testing
- Dance-therapy, Art-therapy, Yoga
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Hospices Civils de Lyon
Complex Regional Pain Syndrome Type I
Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)
Phase 3 Trial of AMBTX-01 (neridronate) for Complex Regional Pain Syndrome Type 1
- Trial name
- CRPS-RISE (NCT07210515)
- Testing
- Neridronate
- Where
- 33 sites in United States
- Volunteers
- 270 people
- Sponsor
- Ambros Therapeutics, Inc.