Clinical trials: CT
Alzheimer Disease, Healthy Volunteer
Neuroinflammation Imaging in AD
This research study is being done to learn more about inflammation in the brain using Positron Emission Tomography/Computed Tomography (PET/CT) imaging in people with Alzheimer's Disease/Mild Cognitive Impairment or healthy…
- Trial name
- NCT04274998
- Testing
- [18F]NOS, [11C]PBR28
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pituitary Adenoma
Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT
This is a prospective case-control study to compare the usefulness of 18F-FDG PET/MRI with that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas.A single dose of 370 Mega-Becquerel (MBq) 18F-FDG will be…
- Trial name
- NCT03404414
- Testing
- 18F-FDG
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Healthy
EXPLORER PET/CT in Healthy Volunteers
The objective of this pilot study is to collect preliminary data using total body scans on a new, first of its kind, FDA 510k-cleared positron emission tomography/computed tomography (PET/CT) scanner, called EXPLORER.
- Trial name
- NCT04110743
- Testing
- EXPLORER PET/CT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Lung Cancer
Low-dose Computed Tomography Screening for Lung Cancer in Relatives With Family History of Lung Cancer
Screening with the use of low-dose computed tomography (LDCT) reduces mortality from lung cancer. Relatives with family history of lung cancer are at increased risk of lung cancer compared to those without a family history in…
- Trial name
- NCT02519972
- Testing
- low dose computed tomography
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Alzheimer's Disease
[18F]AV45(Aβ) and [18F]AV1451(Tau)PET/CT in the Diagnosis of Early Pathological Changes of Alzheimer's Disease
To investigate the primary brain regions of precursors of Alzheimer's disease and Alzheimer's disease by novel molecular probe [18F]AV45(Aβ) and [18F]AV1451(Tau)PET/CT imaging.
- Trial name
- NCT06833645
- Testing
- molecular probe [18F]AV45(Aβ) and [18F]AV1451(Tau)
- Where
- China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Measurements in Mandibular Symphysis
Comparison of Lateral Cephalometric and Cone Beam CT Measurements in Mandibular Symphysis
The goal of this clinical trial is to compare the linear and angular measurements of the mandibular symphyseal region using lateral cephalometric (LC) and cone beam computed tomography (CBCT) images.
- Trial name
- NCT05654844
- Testing
- LC images, CBCT images
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Central Nervous System Disease, MRI
An Explainable Neuroradiologist Artificial Intelligence Assistance System for Brain CT and MRI
This clinic trial aims to validate the working performance of radiologists with or without artificial intelligence (AI) diagnostic tool at neurological diseases diagnosis on brain CT/MRI.
- Conditions
- Central Nervous System Disease, MRI, CT, AI (Artificial Intelligence)
- Trial name
- NCT07167043
- Testing
- AI-assisted diagnostic systems
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Yaou Liu
Hip Osteoarthritis
Prospective Catalystem CT-RSA
Multi-Centre Study in patients undergoing Total Hip Arthroplasty with the Smith+Nephew CATALYSTEM™ Primary Hip System. The primary objective is to establish the mean inferior stem migration (subsidence) of the CATALYSTEM™ stem…
- Trial name
- NCT07698717
- Testing
- CATALYSTEM
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Breast Cancer
Preoperative Immunotherapy Combined With Stereotactic Radiation Therapy Boost in the Treatment of HER2-negative Breast Cancer
The goal of the study is to assess the safety and effectiveness of the combination of anti-PD1 immunotherapy (pembrolizumab) and radiotherapy in the preoperative treatment of HER2-negative breast cancer resistant to classical…
- Trial name
- BREAST-BOOSTER (NCT06472583)
- Testing
- Keytruda, Preoperative radiation therapy
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Lung Cancer, Metastatic Cancer in the Lungs
Early Detection of Lung Cancer Via Bi-plane Correlation Chest Imaging
This project proposes a new method, Bi-plane Correlation Imaging (BCI), for improved detection of subtle lung nodules. In BCI, two digital radiographs of the chest are acquired within a short time interval from slightly different…
- Trial name
- NCT00673283
- Testing
- bi-plane chest radiography
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
To Compare the Pharmacokinetics and Safety of CT-P17 and Humira in Healthy Subjects
This is a Phase 1, Randomized, Double-blind, Three-arm, Parallel group, Single-dose Study to Compare the Pharmacokinetics and Safety of CT-P17 and Humira (US licensed Humira and EU-approved Humira) in Healthy Subjects
- Trial name
- NCT03970824
- Testing
- CT-P17, US-licensed Humira, EU-approved Humira
- Where
- 9 sites in South Korea
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Celltrion
Scapholunate Dissociation
Diagnosing Dynamic Scapholunate Instability with Computer Tomography
Scapholunate instability can result in debilitating pain, dysfunction, and secondary arthritis. If treatment is required, the instability should ideally be addressed in the dynamic stage, before non-reducible non-repairable…
- Trial name
- stressct (NCT06695260)
- Testing
- CT scan
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Regionaal Ziekenhuis Heilig Hart Tienen
Atrial Fibrillation (AF), CT
Cardiac CT Evaluation of EAT in AF vs. Non-AF Subjects
The goal of this cross-sectional study is to explore the relationship between atrial structural characteristics (such as epicardial adipose tissue infiltration and atrial size) and atrial fibrillation (AF), as well as the…
- Trial name
- CCT-EAT-AF-NA (NCT07320261)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- xiaoya wang
Status Epilepticus, Ictal-interictal Continuum
The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus
The investigators propose a prospective study of 20 control subjects and 180 consecutive patients with possible non-convulsive status epilepticus (NCSE). The investigators will obtain three functional images of the brain: 1.
- Conditions
- Status Epilepticus, Ictal-interictal Continuum, Positron-emission Tomography, Perfusion Weighted MRI
- Trial name
- NCT06017973
- Testing
- MRI scan including arterial spin labelling of the brain, CT perfusion scan of the brain, FDG-PET scan of the brain
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Larynx Disease, Laryngeal Stenosis
The Effectiveness of Reconstructive Microsurgery on the Clinical and Functional State of Laryngeal Stenosis
To improve diagnostic methods for patients with laryngeal stenosis for the optimal determination of the technique of surgical treatment.
- Trial name
- NCT04734483
- Testing
- spirometry, MRI and CT, Laryngoscopy
- Where
- 2 sites in Kazakhstan, Russia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Astana Medical University
Amino-Acid Transport Disorder, Primary Hyperparathyroidism
Amino Acid Transporter System PET/CT Imaging in AATS-Related Diseases
To evaluate the potential usefulness of 11C/18F-MET/FET positron emission tomography/ computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various amino acid transporter system (AATS)-related…
- Conditions
- Amino-Acid Transport Disorder, Primary Hyperparathyroidism, Glioma
- Trial name
- NCT07379463
- Testing
- 11C/18F-MET/FET
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Coronary Angiography, Chest Pain
Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)
This is a prospective, randomized multicenter trial comparing MSCT to standard of care (SOC) diagnostic treatment in the triage of Emergency Department (ED) low to intermediate risk chest pain patients.
- Trial name
- CTSTAT (NCT00468325)
- Testing
- Multi-slice computed tomography, Rest-stress Nuclear Myocardial Perfusion Imaging
- Where
- 16 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Endovascular Abdominal Aortic Aneurysm Repair
Contrast Ultrasound in the Surveillance of Endovascular Abdominal Aortic Aneurysm Repair
The purpose of this study is to support the suspected expectation that Contrast enhanced Ultrasound (CUS) detects all endoleaks that have been detected by Computed Tomography (CT), and also find a number of leaks missed by CT.
- Trial name
- NCT01022892
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Adrenal Incidentalomas, Thoracic CT-scan
Artificial Intelligence Used in Screening Adrenal Nodules
By collecting chest low-dose spiral CT plain scan images, extracting effective features from the adrenal gland regions, training and validating an artificial intelligence-based automatic diagnostic algorithm for adrenal nodules…
- Trial name
- NCT07198152
- Testing
- None intervention
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Opioid-Related Disorders
Tau PET Imaging in Opioid Use Disorder
The investigators plan to enroll up to 60 adult subjects in this study. There will be three groups of up to 20 subjects each in this study.
- Trial name
- NCT05651516
- Testing
- 18F-PI-2620 PET/CT
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania