Clinical trials: CT
Bradycardia
Heart Rate Reducing Therapy in Cardiac CT Using Ivabradine and Bisoprolol
Out-patients scheduled for coronary computer tomographic angiography (CCTA) were screened regarding their baseline heart rate. If heart rate was > 75, patients were pretreated with 10mg bisoprolol (group 1) or 10mg bisoprolol…
- Trial name
- NCT02764970
- Testing
- Ivabradine 7.5mg orally
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Hyperthyroidism, Tomography
Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans
The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).
- Conditions
- Hyperthyroidism, Tomography, Emission-Computed, Single-Photon
- Trial name
- NCT02772705
- Where
- 9 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Dementia, Movement Disorders
Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.
The goal of this clinical study is to compare the current standard-of-care PET/CT scanner with the new NeuroEXPLORER PET/CT, with the aim of demonstrating the added diagnostic value of the new scanner.
- Conditions
- Dementia, Movement Disorders, ALS - Amyotrophic Lateral Sclerosis, Epilepsy
- Trial name
- NCT07595666
- Testing
- Standard-of-care PET/CT, NeuroEXPLORER
- Where
- Belgium
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- prof. dr. Koen Van Laere
Colorectal Cancer
Screening for Colorectal Cancer With FOBT, Virtual Colonoscopy and Optical Colonoscopy. A Randomized Clinical Trial in the Florence District
RATIONALE: Computed tomographic colonography (CTC) has proven to be accurate in detecting colorectal neoplasms and may be a primary test in colorectal cancer screening.
- Trial name
- SAVE (NCT01651624)
- Testing
- Invitation to screening
- Where
- Italy
- Volunteers
- 16,087 people, healthy volunteers welcome
- Sponsor
- Cancer Prevention and Research Institute, Italy
Chronic Airway Disease, Interstitial Lung Disease
WTC Chest CT Imaging Archive
Dr. Rafael E de la Hoz and colleagues have performed standardized and computer-assisted readings of all chest CT scans received by WTC workers and volunteers at the Mount Sinai Medical Center between 2003 and 2016.
- Conditions
- Chronic Airway Disease, Interstitial Lung Disease, Lung Cancer
- Trial name
- NCT03295279
- Where
- United States
- Volunteers
- 2,122 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aortic Aneurysm
Dynamic CT Imaging After Nellix Endoprosthesis Implantation
The Nellix Endovascular Sealing Prosthesis (EVAS) endoprosthesis is a new device aimed at prophylactic treatment of abdominal aortic aneurysms. In regular follow up conventional CT-imaging is used for surveillance.
- Trial name
- NCT02438605
- Testing
- Nellix
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Breast Cancer Diagnosis
Comparison of Low-dose Spiral Breast CT With MRI in Major Indications of MRI for Breast Diagnostics
Comparison between two diagnostic modalities for breast cancer diagnosis. Two different imaging systems are compared to evaluate the performance of the two systems
- Trial name
- NCT05989022
- Testing
- Injection of contrast enhancing agent Gadovist for MRI investigation, Injection of contrast enhancing agent Imeron for B-CT investigation
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- AB-CT - Advanced Breast-CT GmbH
Steatotic Liver Disease, Liver Fibrosis Progression in Chronic Liver Disease
Interventional AI-Human Collaboration for Steatotic Liver Disease Screening
Steatotic liver disease (SLD) is one of the most prevalent chronic liver diseases worldwide, affecting nearly 30% of the global population and projected to exceed 55% by 2040.
- Conditions
- Steatotic Liver Disease, Liver Fibrosis Progression in Chronic Liver Disease, Liver Steatosis, Liver Fibrosis
- Trial name
- NCT07613827
- Testing
- AI-human collaboration for SLD screening
- Where
- China
- Volunteers
- 7,969 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
Clinical Evaluation of the ID NOW™ CT/NG Test
The objective of this study is to determine the performance of the ID NOW™ CT/NG test in male urine, female urine, and self-collected vaginal swabs when tested by intended users (i.e., untrained operators).
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Asymptomatic Condition
- Trial name
- NCT06395675
- Testing
- ID NOW™
- Where
- United States
- Volunteers
- 7,100 people, healthy volunteers welcome
- Sponsor
- Abbott Rapid Dx
Cancer of the Lung, Abdominal Cancer
Investigating the Improvement in 4D CT Images Using AV Biofeedback
This study will look at how tumors in the chest and abdomen move when you breathe. Your doctors are studying if extra 4D CT scans and instructions on how to breathe can help predict this type of movement and improve the accuracy…
- Trial name
- GCC0832 (NCT00780611)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Coronary Artery Disease
Virtual Coronary Intervention and Non-invasive Fractional Flow Reserve (FFR)
The investigators examined the feasibility of treatment planning using virtual coronary revascularization and fractional flow reserve (FFR) CT before the invasive procedures.
- Trial name
- NCT01478100
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pneumonia, Viral, COVID-19 Pneumonia
AI-based System for Assessing Suspected Viral Pneumonia Related Lung Changes
The AI-based system designed to process chest computed tomography (CT) aims to 1) detect the presence of pathologic patterns associated with interstitial changes in pneumonia; 2) highlight areas on the images with the probable…
- Trial name
- NCT06501599
- Testing
- Medical software (AI-based system)
- Where
- Russia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Lower Limb Deformity, Anterior Knee Pain Syndrome
Is Gait Analysis for Proposed Rotational Deformities a Useful Resource
Rotational deformities, such as femoral (thigh bone) and tibial (leg bone) torsion, are established causes of patellofemoral (kneecap joint) pain and instability.
- Conditions
- Lower Limb Deformity, Anterior Knee Pain Syndrome, Patellofemoral Pain, Rotation; Deformity
- Trial name
- NCT05576064
- Testing
- Gait analysis
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Coronary Angiography, Obesity
Optimizing Image Quality in Obese Patients Undergoing Coronary Computed Tomography (CT) Angiography
The purpose of this cardiovascular imaging research is to look at ways to improve the way we can look at the pictures of the heart.
- Conditions
- Coronary Angiography, Obesity, Coronary Disease
- Trial name
- BMI40 (NCT00468195)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Premature Birth, Infant Development
Neonatal Experience of Social Touch
The purpose of this randomised control trial is to determine the efficacy of CT-optimal touch (gentle stroking at 3cm/s) for newborn's who require a heel prick.
- Conditions
- Premature Birth, Infant Development, Pain
- Trial name
- NEST (NCT05039918)
- Testing
- Affective touch
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Lung Diseases
American Lung Association (ALA) Lung Health Cohort
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease.
- Trial name
- NCT04543461
- Where
- 37 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Subjects, Rheumatoid Arthritis
Biodistribution, Dosimetry and Performance of [68Ga]Ga-DOTA-Siglec-9 in Healthy and Patients With Rheumatoid Arthritis, Vasculitis or Pulmonary Sarcoidosis
This study evaluates safety, tolerability, biodistribution and performance of the [68Ga]Ga-DOTA-Siglec-9 following a single intravenous administration in patients with active rheumatoid arthritis, vasculitis or pulmonary…
- Conditions
- Healthy Subjects, Rheumatoid Arthritis, Vasculitis, Pulmonary Sarcoidosis
- Trial name
- SIGLEC (NCT03755245)
- Testing
- [68Ga]Ga-DOTA-Siglec-9
- Where
- Finland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Glioma
68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-Aca-BBN(7-14) in glioma patients.
- Trial name
- NCT02520882
- Testing
- 68Ga-NOTA-Aca-BBN, PET/CT
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Caries, Diagnoses Disease
Evaluation of Caries Detection Methods
The investigators aim will be to compare the diagnostic performance of clinical visual examination (ICDAS II), intraoral/bite wing radiography (BW), near infrared light transillumination (NIR-LT), and laser fluorescence (LF), in…
- Trial name
- NCT05064566
- Testing
- caries assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Nazan Kocak Topbas
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital