Clinical trials: CT Coronary Angiography
Coronary Artery Disease, Aortic Aneurysm
Computed Tomography Dose Reduction Using Sequential or Fast Pitch Sprial Technique
This is a prospective, controlled observational trial of patients undergoing clinically indicated cardiothoracic computed tomography (CT), including pulmonary or aortic angiography and coronary CT angiography (CCTA).
- Conditions
- Coronary Artery Disease, Aortic Aneurysm, Pulmonary Embolism
- Trial name
- CTDOSE (NCT01272453)
- Where
- 9 sites in United States, Saudi Arabia
- Volunteers
- 2,640 people
- Sponsor
- Gilbert L. Raff, MD
Coronary Artery Disease, Atherosclerosis
Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
The purpose of this study is to evaluate the role of coronary CT angiogram (CCTA) as a superior guide for the assessment of coronary artery plaque and guiding treatment decisions.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Heart Attack
- Trial name
- ARTCAP (NCT06280976)
- Testing
- Statin, Aspirin tablet, Nexlizet
- Where
- United States
- Sponsor
- University of Louisville
Stable Ischemic Heart Disease, Coronary Artery Disease
Evaluation of Diagnostic Accuracy, Safety, and Cost-Effectiveness of the Non-Invasive Cardiolens FFR-CT Pro Method to Measure the Fractional Flow Reserve in Diagnostics of Chronic Coronary Syndromes Versus the Standard Diagnostic Modalities.
A multicentre, post-marketing, observational trial in 450 patients, whose standard diagnostic workup for chronic coronary syndromes provided for Invasive Coronary Angiography (ICA).
- Trial name
- NCT04777513
- Testing
- CCTA (Coronary Computed Tomography Angiography), ICA (Invasive Coronary Angiography), FFR (Fractional Flow Reserve)
- Where
- 11 sites in Poland
- Volunteers
- 450 people
- Sponsor
- Hemolens Diagnostics Sp. z o.o.
Aortic Aneurysm
Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta
An in-house calculator was developed to calculate the appropriate contrast dose, rather than standardly administering a 120ml dose.
- Trial name
- NCT05716568
- Testing
- Contrast dose reduction, CT-angiography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Disease
Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A 100kV Protocol
The objective of this study is to compare radiation dose of a 100kV scan protocol to the standard 120kV scan protocol. We hypothesize that the 100kV scan protocol is associated with a reduction in dose estimates of at least 20%…
- Trial name
- PROTECTION-II (NCT00611780)
- Testing
- tube voltage
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease (CAD), Computed Tomography Angiography
AI-assisted CT for Risk Stratification in Coronary Artery Disease (ACTION)
The goal of this observational study is to learn if AI-assisted cardiac CT imaging can improve cardiovascular risk stratification and prediction of future coronary events in an adult population undergoing clinically indicated…
- Conditions
- Coronary Artery Disease (CAD), Computed Tomography Angiography, Biomarkers, AI (Artificial Intelligence)
- Trial name
- ACTION (NCT07577609)
- Where
- Ireland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Galway
Chest Pain, Acute Coronary Syndrome
Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
This multi-center, randomized, controlled trial conducted in Emergency Departments (ED) compares computed tomography (CT) coronary angiography with the traditional approach (usual care) for low- to intermediate-risk chest pain…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00933400
- Testing
- CT Coronary Angiography (CTCA), Traditional Strategy
- Where
- 5 sites in United States
- Volunteers
- 1,392 people
- Sponsor
- American College of Radiology
Coronary Artery Disease
A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients
To assess diagnostic accuracy,image quality and renal safety of a double low-dose coronary CTA protocol at coronary artery evaluation in patients with diabetes by using invasive coronary angiography(ICA) as the reference method…
- Trial name
- NCT04342455
- Testing
- double-low scanning
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Coronary Artery Disease
Multislice CT Angiography of Coronary Bifurcations and Outcomes After Intervention
This is prospective, observational study, that will be conducted in two high-volume university interventional cardiology centers.
- Trial name
- NCT01943643
- Testing
- multislice CT angiography
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- Clinical Hospital Center Zemun
Coronary Artery Disease
Computed Tomography-derived Fractional Flow Reserve vs. Angiographic Quantitative Flow Ratio in Management of Patients With Coronary Artery Disease
This is a multi-center, randomized controlled trial to compare the clinical outcomes between CT-derived fractional flow reserve (CT-FFR) guided strategy and angiography-derived quantitative flow ratio (QFR) guided strategy among…
- Trial name
- CONQUER (NCT07308496)
- Testing
- CT-FFR guided strategy, QFR guided strategy
- Volunteers
- 1,402 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Role of On-site CT-derived FFR in the Management of Suspect CAD Patients
The primary of this registry is to evaluate whether the availability of CTA/CT-FFR procedure could effectively optimize the flow of clinical practice of stable chest pain versus conventional clinical pathway in decision making…
- Trial name
- TARGET (NCT03901326)
- Testing
- CT-FFR assessment
- Where
- China
- Volunteers
- 1,216 people
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease
AI-Based CT Analysis of Coronary Plaque Evolution
This retrospective, multicenter, observational study will evaluate an artificial intelligence-based system for quantitative assessment and risk stratification of coronary atherosclerotic plaque.
- Trial name
- AI-CT-PLAQUE (NCT07886996)
- Where
- 5 sites in China
- Volunteers
- 326 people
- Sponsor
- Zhejiang Hospital
Coronary Artery Disease
Fractional Flow Reserve Derived From Computed Tomography Coronary Angiography in the Assessment and Management of Stable Chest Pain
To determine whether, in a population of patients presenting to the rapid access chest pain clinic (RACPC), routine FFRct (Fractional Flow Reserve Computed Tomography) as a default test is superior in terms of resource…
- Trial name
- FORECAST (NCT03187639)
- Testing
- FFRct, Standard care
- Where
- United Kingdom
- Volunteers
- 1,400 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Coronary Artery Disease
Comparison of Digital Electronic Stethoscope to Computed Tomography (CT) Angiography in Detection of Coronary Artery Disease
The study is designed to evaluate the predictive diagnostic accuracy of SonoMedica's CardioSond digital electronic stethoscope in the detection of coronary artery disease (CAD) in patients without known disease who are referred…
- Trial name
- NCT01040923
- Testing
- CardioSond Cardiac Sonospectrographic Analyzer
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- SonoMedica, Inc.
Coronary Atherosclerosis
Evaluation of Subclinical COronary Atherosclerosis for Risk Stratification Using Coronary Computed Tomography (CT) Angiography
To evaluate the prognostic value of coronary CT angiography (CCTA) for risk stratification in asymptomatic adults in comparison with conventional risk stratification (CRS) and coronary artery calcium scoring (CACS).
- Trial name
- ESCORT (NCT01416532)
- Where
- South Korea
- Volunteers
- 5,000 people
- Sponsor
- Seoul National University Bundang Hospital
Coronary Artery Disease
Risk Evaluation by COronary CTA and Artificial IntelliGence Based fuNctIonal analyZing tEchniques - II
This study is a multicenter, prospective clinical cohort study. The study intends to continuously enroll patients with coronary heart disease.
- Trial name
- RECOGNIZE-II (NCT05856110)
- Where
- 9 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Ruijin Hospital
Coronary Artery Disease
Risk Evaluation by COronary CTA and Artificial intelliGence Based fuNctIonal analyZing tEchniques - I
This study is a multicenter, retrospective imaging study. The study intends to retrospectively enroll patients with acute myocardial infarction who had received coronary CTA in a certain time-window before this event.
- Trial name
- RECOGNIZE-I (NCT05884008)
- Where
- 9 sites in China
- Volunteers
- 300 people
- Sponsor
- Ruijin Hospital
Ischemic Stroke, Myocardial Ischemia
Coronary Arteriosclerosis in Patients With Acute Ischemic Stroke
The specific objectives of this thesis are in a cohort of patients with an acute ischemic stroke, 1. To establish the degree of coronary arteriosclerosis. 2.
- Conditions
- Ischemic Stroke, Myocardial Ischemia, Coronary Arteriosclerosis
- Trial name
- CORAIS (NCT00701818)
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Vejle Hospital
Chest Pain, Acute Coronary Syndrome
AI-Assisted Interpretation of Cardiac CT in the Emergency Department
" This prospective, pragmatic, randomized controlled trial is designed to evaluate the impact of an artificial intelligence (AI)-based coronary computed tomography angiography (CCTA) interpretation tool (Angiomics) on emergency…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- NCT07235657
- Testing
- Angiomics AI-based Coronary CT Interpretation Tool, Standard CCTA Interpretation without AI
- Where
- South Korea
- Volunteers
- 530 people
- Sponsor
- Yonsei University