Clinical trials: CT Scan
Delayed Union Fracture, CT-scan
A mRUS Validation Study for Nail-treated Fractures of Long Bones and a TUS Exploratory Study for Nail and Plate-treated Fractures of Long Bones
Early intervention attempts to shorten protracted delayed union (DU) or prevent non-union (NU) fractures are hampered by lack of validated quantitative assessment tools for bone fracture healing during normal and delayed healing…
- Conditions
- Delayed Union Fracture, CT-scan, X-Ray, Bone Fracture
- Trial name
- mRUSTUS (NCT03286270)
- Where
- 4 sites in Germany
- Volunteers
- 173 people
- Sponsor
- Bone Therapeutics S.A
Lung Cancer
The DANTE Trial. A Randomized Study on Lung Cancer Screening With Low-Dose Spiral Computed Tomography
High survival rates have been reported for screen-detected Stage I lung cancer patients, but there are concerns about the potential biases of uncontrolled studies.
- Trial name
- NCT00420862
- Testing
- Spiral Computed Tomography
- Where
- Italy
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Metastatic Seminoma
Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma
This study evaluated the safety, efficacy and toxicity of carboplatin area under the curve (AUC)-10 in metastatic seminoma to see if, by using fluoro-deoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) to…
- Trial name
- Car-PET (NCT02272816)
- Testing
- Carboplatin AUC-10
- Where
- 2 sites in United Kingdom
- Volunteers
- 48 people
- Sponsor
- Barts & The London NHS Trust
Ureteral Calculi, Hydronephrosis
Evaluating Ureteral Length Using Computed Tomography (CT)
Proper selection of ureteral stent length might help in reducing comorbidities associated with ureteral stenting, currently there is no standardized way of measuring ureteral length.
- Conditions
- Ureteral Calculi, Hydronephrosis, Ureteral Obstruction
- Trial name
- URO-Y-2 (NCT01542593)
- Testing
- Ureteral catheterization - Cook Urological Inc. open end ureteral catheter 5FR
- Where
- Israel
- Volunteers
- 53 people
- Sponsor
- Carmel Medical Center
Stable Angina, Coronary Artery Disease
CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
The "DATASET-PRECISE", a 3-arm parallel randomized study, aims to provide new insights in risk stratification of patients with suspected CAD in the Greek population.
- Conditions
- Stable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery Calcification
- Trial name
- DATASET (NCT04424121)
- Testing
- CCTA
- Where
- 3 sites in Greece
- Volunteers
- 900 people
- Sponsor
- Aristotle University Of Thessaloniki
Regional Anesthesia, Computed Tomography
Radiological Study of PENG Block Depth
This study evaluates the depth of anatomical landmarks required in regional anaesthesia to perform either Femoral Nerve Block or PENG Block.
- Conditions
- Regional Anesthesia, Computed Tomography, Anatomical Description
- Trial name
- Tomo-PENG (NCT04337164)
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronary Artery Disease, Atherosclerosis
PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Early detection of coronary atherosclerotic disease facilitates adequate prevention. The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography / computed…
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary Atherosclerosis of Native Coronary Artery
- Trial name
- PET; CT (NCT05994014)
- Testing
- PET/CT
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Predictive Role of Photon Counting Computed Tomography in Acute Coronary Syndrom Patients
For patients with severe calcification or complex non-calcified plaques, we investigate wether PCCT can enable non-invasive, in vivo precise differentiation and quantitative measurement of plaque components (e.g., spotty…
- Trial name
- NCT07536607
- Testing
- there is no intervention in this study
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Chinese PLA General Hospital
Alpha 1-Antitrypsin Deficiency
Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE)
The goal of this trial was to explore the utility of evaluating emphysema progression through CT scans measuring lung density during a 2 year period of weekly infusions of either placebo or human alpha-1-antitrypsin (AAT…
- Trial name
- NCT00263887
- Testing
- Alpha1-Proteinase Inhibitor (Human), Albumin (Human) 20%, United States Pharmacopeia (USP)
- Where
- 3 sites in Denmark, Sweden and 1 more
- Volunteers
- 77 people
- Sponsor
- Grifols Therapeutics LLC
Coronary Disease
Prospective Randomized Trial On RadiaTion Dose Estimates Of CT AngIOgraphy In PatieNts Scanned With A Sequential Scan Protocol
The objective of this study is to compare radiation dose of a standard spiral scan with the a new sequential scan protocol. We hypothesize that the sequential scan protocol is associated with a reduction in dose estimates of at…
- Trial name
- PROTECTION-III (NCT00612092)
- Testing
- Spiral image acquisition, sequential image acquisition
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Coronary Artery Disease
Computed Tomography-derived Fractional Flow Reserve vs. Angiographic Quantitative Flow Ratio in Management of Patients With Coronary Artery Disease
This is a multi-center, randomized controlled trial to compare the clinical outcomes between CT-derived fractional flow reserve (CT-FFR) guided strategy and angiography-derived quantitative flow ratio (QFR) guided strategy among…
- Trial name
- CONQUER (NCT07308496)
- Testing
- CT-FFR guided strategy, QFR guided strategy
- Volunteers
- 1,402 people
- Sponsor
- China National Center for Cardiovascular Diseases
Prostatic Neoplasms
Cone Beam CT for Daily Image Guidance - Prostate Cancer
Conformal dose escalated radiation therapy (CRT) is standard treatment for patients with low and intermediate risk prostate cancer.
- Trial name
- NCT00188786
- Testing
- daily Cone Beam CT for imaging guidance for radiotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Hyperthyroidism, Hypothyroidism
Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism
The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder
- Trial name
- NCT02005250
- Where
- Denmark
- Volunteers
- 93 people
- Sponsor
- Steen Bonnema
Traumatic Brain Injury, Computed Tomography
Evaluation of Pediatric Procedural Sedation With Rectal Chloral Hydrate or Intranasal Midazolam
Thousands of children receive sedation for diagnostic and therapeutic interventions annually, and this number is expected to increase. Children are at higher risk for sedation-related complications than adults.
- Conditions
- Traumatic Brain Injury, Computed Tomography, Procedural Sedation
- Trial name
- NCT01402596
- Testing
- Midazolam, Chloral Hydrate
- Where
- Brazil
- Sponsor
- University of Sao Paulo
Psoriatic Arthritis
Distal Erosions and Nail Psoriasis
Nearly 30% of patients with cutaneous psoriasis (PsO) developed psoriatic arthritis (PsA). Among these patients 20 % will have severe destructive arthritis.
- Trial name
- PSUPSO (NCT02813720)
- Testing
- HR-pQCT High resolution peripheral quantitative CT-scan
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Coronary Artery Disease
Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients With Prior Equivocal Stress Test for Detection of Coronary Artery Disease
Background: Noninvasive cardiac stress testing is imperfect. Inconclusive test results generate further expensive testing. In patients with known or suspected coronary artery disease, both computed tomography (CT) and magnetic…
- Trial name
- NCT00929227
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome, Myocardial Infarction
Rule Out Myocardial Infarction by Computer Assisted Tomography
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
- Trial name
- ROMICAT (NCT00990262)
- Testing
- Cardiac Computed Tomography
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Massachusetts General Hospital
Pseudoarthrosis of Bone
SPECT/CT Bone Scan Quantification Surgery
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
- Trial name
- PERQUAL (NCT05183542)
- Testing
- Bone scan
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Heart Failure
SPECT-based Prediction and Evaluation of CRT Efficacy in CHF
This study evaluates the state of the cardiac sympathetic activity and the severity of ventricular dyssynchrony in chronic heart failure patients and assesses the capabilities of radionuclide indication methods in determining the…
- Trial name
- MIBGinCRT (NCT03667989)
- Testing
- Assessment of cardiac sympathetic innervation by 123I-MIBG
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Acute Stroke
The Dutch Acute Stroke Trial (DUST): Prediction of Outcome With Computed Tomography (CT) - Perfusion and CT-angiography
Less than 10% of all ischemic stroke patients are treated by intravenous thrombolysis (IVT) as most present later than the accepted 3 hour time window.
- Trial name
- DUST (NCT00880113)
- Testing
- Non-contrast CT, CT-perfusion and CT-angiography
- Where
- 14 sites in Netherlands
- Volunteers
- 1,500 people
- Sponsor
- UMC Utrecht
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