Clinical trials: CVA
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Following Transient Ischemic Attack and Minor Stroke
Rationale: To date, anticoagulant therapy in acute stroke has also been limited by excess hemorrhagic events. The oral anticoagulant dabigatran is a novel agent, which has been shown to be associated with much lower intracranial…
- Trial name
- DATAS II (NCT02295826)
- Testing
- Dabigatran, Acetylsalicylic acid
- Where
- 6 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Ischemic Stroke, Intracranial Hemorrhages
Novel Oral Anticoagulants in Stroke Patients
The present study will monitor and explore acute neurovascular emergencies in patients treated with NOACs compared to those under treatment with VKAs.
- Trial name
- NOACISP (NCT02353585)
- Where
- Switzerland
- Volunteers
- 1,050 people
- Sponsor
- University Hospital, Basel, Switzerland
Ischemic Stroke
Navigated Transcranial Magnetic Stimulation in Monitoring Stroke Recovery
The past 10 years of research in persons more than 6 months post stroke have shown certain types of rehabilitation can help "re-wire" the brain.
- Trial name
- NCT01005394
- Testing
- Navigated TMS examination
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nexstim Ltd
Stroke
Effects of the Action Observation Therapy and Robotic Rehabilitation on the Upper-Limb Motor Function in Stroke
This protocol will investigate the effects of action observation therapy and robotic rehabilitation on upper extremity motor functions in subacute stroke patients.
- Trial name
- NCT05590156
- Testing
- Conventional Rehabilitation, Robotic Rehabilitation (ExoRehab X), Action Observation Therapy (AOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Emre Şenocak
Hemiplegic Shoulder Pain
Comparison of Effectiveness of Low Dose Laser and Transcutaneous Electrical Stimulation in Hemiplegic Shoulder
The primary aim of this study is to compare the efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) and Low Level Laser Therapy (LLLT), which are analgesic modalities that play an important role in the treatment of…
- Trial name
- NCT07203222
- Testing
- Low Dose Laser, TENS, Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara Etlik City Hospital
Acute Ischemic Stroke Patients
Hyperglycemia as a Prognostic Factor In Acute Ischemic Stroke Patients
Background: Hyperglycemia is encountered in 20% to 40% of acute stroke patients, with or without a pre-morbid diagnosis of diabetes mellitus.
- Trial name
- NCT04196322
- Testing
- observational study
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Stroke, Hemiparesis
Neural Mechanisms of Music Intervention Chronic Arm Hemiparesis Following Stroke: A Single Case Series EEG Study
The aims of the study are to recruit five participants with stroke upper limb hemiparesis and determine the effects on neural reorganisation of a three-week music intervention using electroencephalogram measures.
- Conditions
- Stroke, Hemiparesis, Home-based
- Trial name
- NCT06223529
- Testing
- Therapeutic Instrumental Music Performance
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Anglia Ruskin University
Post Stroke Epilepsy, Post Stroke Seizure
International Post-Stroke Epilepsy Research Repository
The International Post-Stroke Epilepsy Research Repository (IPSERR): The study aims to collate and categorize data reported by post-stroke epilepsy (PSE) researchers and lodge it within the IPSERR.
- Conditions
- Post Stroke Epilepsy, Post Stroke Seizure, Stroke, Epilepsy
- Trial name
- IPSERR (NCT06108102)
- Testing
- Presence of stroke, either ischemic or hemorrhagic (intracerebral and subarachnoid)
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- Yale University
Post-stroke Upper Limb Spasticity
IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Post-stroke Spasticity of the Upper Limb
IncobotulinumtoxinA (Xeomin) is a botulinum toxin type A preparation free from complexing proteins, i.e. free from proteins other than the active toxin.
- Trial name
- NCT00432666
- Testing
- IncobotulinumtoxinA (Xeomin)
- Where
- 3 sites in Czechia, Hungary and 1 more
- Volunteers
- 148 people
- Sponsor
- Merz Pharmaceuticals GmbH
Stroke Due to Basilar Artery Occlusion, Acute Cerebrovascular Accidents
Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical Treatment
This trial will provide valuable insights into the safety and efficacy of endovascular treatment for acute ischemic stroke patients with basilar artery occlusion within 8 hours of estimated occlusion time.
- Trial name
- BEST (NCT02441556)
- Testing
- endovascular treatment, standard medical therapy
- Where
- 44 sites in China
- Volunteers
- 131 people
- Sponsor
- Xinfeng Liu
Ischemic Stroke
Clinical Study on Huatuo Zaizao Pills for Post-stroke Treatment
The purpose of this study was to evaluate the improvement of limb motor function and nerve function of patients with HTZZ during stroke rehabilitation.
- Trial name
- NCT04910256
- Testing
- Huatuo Zaizao Pills, Basic treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Sarcopenia, Stroke, Acute
Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients
The primary aim of the study is to assess the mobility dose in neurocritical care patients with ischemic stroke or intracranial hemorrhage and its effects on discharge disposition and patient outcomes.
- Conditions
- Sarcopenia, Stroke, Acute, Muscle Weakness, Critical Illness
- Trial name
- NCT03347656
- Where
- 3 sites in United States, Germany
- Volunteers
- 164 people
- Sponsor
- Beth Israel Deaconess Medical Center
Atrial Fibrillation, Left Atrial Appendage
AMPLATZER Cardiac Plug (ACP) Latin American Post Market Observational
The ACP device will be clinically evaluated through a prospective, open-label, nonrandomized, multi-center post market clinical study.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage, Stroke
- Trial name
- ACP LA (NCT01962051)
- Testing
- Amplatzer Cardiac Plug
- Sponsor
- Abbott Medical Devices
Stroke, Ischemic, Cognitive Decline
Post-stroke Immunological Changes in Young Stroke Patients
In the present study, the investigators aim to elucidate the role of T-cells on cognitive decline in younger stroke patients, using repeated cognitive testing, brain imaging, and immunological analyses in the first 6 month after…
- Trial name
- NCT03725137
- Testing
- Analysis of T-lymphocytes
- Volunteers
- 77 people
- Sponsor
- University Medicine Greifswald
Aphasia, Acquired
PCT for Speech, Language, and Cognitive Intervention in Stroke Patients
Given the evolving uses of technology in rehabilitation, the investigators aimed to measure the change in aphasia severity using PCT App, a digital therapeutic adapted from Constant Therapy (CT), a dynamic, personalized therapy…
- Trial name
- NCT04488029
- Testing
- PCT, Workbooks
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- The Learning Corp
Stroke, Acute
The Temporal Cellular Landscape of the Adaptive Immune System in Patients With Acute Stroke
Despite novel acute therapies the global burden of stroke remains high worldwide. Targeting the immune response after stroke has the potential to improve recovery in all stroke patients.
- Trial name
- TAPAS (NCT04852445)
- Where
- Netherlands
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Ischemic Stroke
Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China
The SAMMPRIS suggested that aggressive treatment was superior to intravascular stenting in patients with severe symptomatic intracranial atherosclerotic stenosis (ICAS) due to high complication rate in patients in stenting group.
- Trial name
- NCT01968122
- Testing
- intravascular stent therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongrong Miao
Stroke, Upper Extremity Paresis
Cortical Enhancement of Posture, Movement Planning, and Execution of Upright Reaching Following Stroke
Stroke is the leading cause of disability and diminished quality of living that frequently includes impairments of postural control and upper extremity (UE) function.
- Trial name
- NCT04308629
- Testing
- Transcranial direct current stimulation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stroke, Hand
Comparative Effects of Sensorimotor Interventions on Hand Performance With Stroke
This randomized controlled trial investigated the comparative effects of sensory, motor, and combined sensorimotor interventions on hand motor function and behavioral performance in patients with stroke.
- Trial name
- NCT07590245
- Testing
- Sensory and Motor Exercise Group, The Sensory Exercise Group, The Motor Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Atlas University
Aphasia, Stroke
Adaptive Trial Scheduling in Naming Treatment for Aphasia
Aphasia is a language disorder caused by stroke and other acquired brain injuries that affects over two million people in the United States and which interferes with life participation and quality of life.
- Trial name
- NCT05653466
- Testing
- Adaptive Spacing Condition, High-Item Non-Adaptive Spacing Condition, Low-Item Non-Adaptive Spacing Condition
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh