Clinical trials: CVD Risk Factors
Cardiovascular Diseases
Wearable Devices to Promote Physical Activity
This study evaluates the effect of a new wearable device, that measures physical activity level based on heart rates, on relevant health outcomes including cardiorespiratory fitness.
- Trial name
- HUNT4-PAI (NCT03270202)
- Testing
- PAI group, Usual care
- Where
- Norway
- Volunteers
- 175 people
- Sponsor
- Norwegian University of Science and Technology
Hypertension
ABG+/GarlACE Effects on Cardiovascular Risk Factors in Subjects With Grade I Hypertension
The goal of this clinical trial is to evaluate the dose response effect on cardiovascular disease risk factors of a Black Garlic Extract in subjects with Grade I Hypertension.
- Trial name
- GARDOSE (NCT06264622)
- Testing
- Low dose, High dose
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Pre-eclampsia, Obesity
ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes
Obesity is a growing problem in East London and every other woman who enters pregnancy is obese or overweight. In addition to obesity, other metabolic risk factors such as raised lipids, high blood pressure and diabetes increase…
- Conditions
- Pre-eclampsia, Obesity, Raised Lipids, High Blood Pressure
- Trial name
- ESTEEM (NCT02218931)
- Testing
- Targeted ESTEEM diet, Non-randomised cohort
- Where
- United Kingdom
- Volunteers
- 3,442 people
- Sponsor
- Queen Mary University of London
Osteoarthritis, Cardiovascular Risk Factors
Osteoarthritis Cardiovascular Risk Factors
We analyze retrospectively the relationship between traditional cardiovascular risk factors as hypertension, obesity, dislipidemia and diabetes and hand or knee osteoarthritis and we compare the results with a control groups of…
- Conditions
- Osteoarthritis, Cardiovascular Risk Factors, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT01902654
- Testing
- Cardiovascular risk factors diagnoses collection., History of cardiovascular disease, Cardiovascular risk factors association
- Where
- Spain
- Volunteers
- 490 people
- Sponsor
- Parc Taulí Hospital Universitari
Cardiovascular Risk Factor
Effect Levosimendan Administration on Postoperative NT-proBNP in Cardiac Risk Patients
This is a prospective randomised trial investigating the effect of a preemptive administration of levosimendan on postoperative cardiac NT-proBNP concentrations.
- Trial name
- IMPROVE (NCT04329624)
- Testing
- Levosimendan
- Where
- Austria
- Volunteers
- 230 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Hypertension
Strengthening Primary Healthcare Delivery for Diabetes and Hypertension in Eswatini
The WHO-PEN@Scale project is a three-arm cluster-randomized trial that is investigating the population-level effects of a healthcare reform in Eswatini, which aims to strengthen primary care for diabetes and hypertension.
- Trial name
- NCT04183413
- Testing
- DSD, CDP
- Where
- Eswatini
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Ankle Brachial Index
Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population
Peripheral arterial disease (PAD) is a common clinical manifestation of the systemic atherosclerotic process, and the ankle brachial index (ABI) is an ideal tool to diagnose PAD.
- Trial name
- abilities (NCT03616418)
- Testing
- antiplatelet drugs;statins;antihypertensive drugs
- Volunteers
- 3,026 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Cardiovascular Diseases, Cardiovascular Risk Factor
Local Antioxidant Therapy Vasoconstriction Effects in Different Races
Cardiovascular disease (CVD) afflicts nearly one-third of the adult population with all races and ethnicities represented in CVD prevalence.
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction
- Trial name
- NCT03684213
- Testing
- Control (Norepinephrine), Norepinephrine + Ascorbic Acid, Norepinephrine + L-NAME
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Obesity, Cardiovascular Disease
Role of Cardiometabolic Risk Factors in Childhood Bone Development
The proposed research brings together complementary expertise to systematically elucidate the longitudinal effects of (1) total and regional body fat and (2) the metabolic impairment that accompanies obesity on bone development…
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes, Osteoporosis
- Trial name
- NCT02355717
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Augusta University
Lipid Metabolism Disorders
Influence of Additional Physician's Consultations and Short Message Service (SMS) Reminders to Patient Compliance
A systematic collection of retrospective and prospective data based on non-interventional patient observation, aimed to assess the risks, course and outcomes of a disease or a group of diseases: the retrospective part: database…
- Trial name
- 3P (NCT04863274)
- Testing
- atorvastatin
- Where
- Russia
- Volunteers
- 2,912 people
- Sponsor
- The League of Clinical Research, Russia
Wearable Device, Cardiovascular Disease
HEARTS in Sync + CardioWatch 287-2
The goal of this interventional study is to evaluate the implementation, usability, and clinical outcomes of a wearable medical-grade device in a virtual Cardiac Rehabilitation (CR) program, titled HEARTS in Sync.
- Conditions
- Wearable Device, Cardiovascular Disease, ASCVD Management, CHF - Congestive Heart Failure
- Trial name
- NCT07322510
- Testing
- Remote Patient Monitoring with Corsano CardioWatch 287-2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Staphylococcus Aureus Bacteremia, Infective Endocarditis
Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia (ET-AUREUS Study).
The goal of this prospective interventionist cohort study is to assess the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteremia at low risk of this complication.
- Trial name
- ET-AUREUS (NCT05862025)
- Testing
- Echocardiography evaluation
- Where
- Spain
- Volunteers
- 470 people
- Sponsor
- Puerta de Hierro University Hospital
Ischemic Stroke, Coaching
Telerehabilitation-Based Coaching Interventions (TeleSCoP) for Patients With Ischemic Stroke
Ischemic stroke has high morbidity and mortality worldwide. Stroke patients experience physical, psychological, and social problems, and require rehabilitation.
- Trial name
- NCT05940350
- Testing
- Telerehabilitation Stroke Coaching of Program (TeleSCoP) group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Acute Coronary Syndrome
Healthy Heart Habits-2
Sixty adults who have experienced acute coronary syndrome within the past 2-12 months from three states (Rhode Island, North Carolina, Minnesota) will be randomized to either (1) a coaching program for depressed mood and health…
- Trial name
- HHH-2 (NCT06440278)
- Testing
- Behavioral Activation for Health and Depression (BA-HD), Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- The Miriam Hospital
Peripheral Vascular Disease
Systematic Assessment of Vascular Risk
It is hypothesized that patients with vascular disease are undertreated for modifiable risk factors, leading to increased morbidity and mortality in this population.
- Trial name
- NCT00378040
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- University Health Network, Toronto
Cardiovascular Diseases, Hyperlipidemia
Efficacy of Ezetimibe/Simvastatin 10/20 mg and MK0524A (1-2 g/Day) in Mixed Hyperlipidemia and Two or More Risk Factors
To measure the percentage of patients who achieve all the treatment lipid goals being treated with ezetimibe/simvastatin 10/20 with or without MK0524A (1-2 g/day).
- Trial name
- NCT00738985
- Testing
- ezetimibe/simvastatin 10/20 mg + MK0524A
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Cardiovascular Diseases
Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
The objective is to, among obese adolescents, study impact of regular physical activity or metformin therapy on nocturnal blood pressure and related cardiovascular disease risk factors.
- Trial name
- NCT00889876
- Testing
- Metformin group, Exercise
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Maria Sandberg Westerstahl
Blood Pressure, Hypertension
PACESETTER: Program to Avoid Cerebrovascular Events Through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor
Program to Avoid Cerebrovascular Events through Systematic Electronic Tracking and Tailoring of an Eminent Risk-factor (PACESETTER) aims to assess the incorporation of its stroke intervention into 2 safety net/academic health…
- Conditions
- Blood Pressure, Hypertension, Mhealth
- Trial name
- NCT03401489
- Testing
- PACESETTER
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Northern California Institute of Research and Education
Myocardial Infarction
GlObal Secondary Prevention strategiEs to Limit Event Recurrence After Myocardial Infarction. GOSPEL Study
Cardiac rehabilitation programmes are a proven treatment for individuals with recent myocardial infarction, resulting in reduced morbidity and mortality compared to usual care.
- Trial name
- NCT00421876
- Testing
- multifactorial continued educational - behavioural programme
- Where
- 74 sites in Italy, Switzerland
- Volunteers
- 3,200 people
- Sponsor
- Heart Care Foundation
COPD, COPD Exacerbation Acute
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a treatable but debilitating medical condition associated with persistent symptoms and chronic airflow obstruction.
- Conditions
- COPD, COPD Exacerbation Acute, Comorbid Chronic Lung Disease on Heart Failure, Mortality
- Trial name
- ICoRe (NCT06652776)
- Testing
- Pharmacological treatment
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- University of Milan