Clinical trials: Caesarean
Vaginal Birth After Cesarean
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Trial name
- NCT00294411
- Testing
- elective cesarean section
- Sponsor
- Chinese University of Hong Kong
Hypotension Drug-Induced
Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
The aim of this study was to compare between crystalloid versus crystalloid and colloid combination preloads for prevention of hypotension following intrathecal anaesthesia in patients undergoing elective Caesarean section.
- Trial name
- NCT03465943
- Testing
- Ringer, Voluven
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Postoperative
The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Dexamethasone is one of many adjuncts tested to prolong the duration of spinal anesthesia and its analgesic effect. The intent of this, a single-site, double-blinded, randomized controlled trial, is to determine if a single…
- Trial name
- NCT04624360
- Testing
- Dexamethasone
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Caesarean Section
Comparison of Postoperative Pain Between Patients Received Primary and Repeated Caesarean Section
To everyone knows, more and more patients received repeated caesarean section in China. However, at present it is not known what is it like about their postoperative pain intensity, and is it different from those patients who…
- Trial name
- NCT03009955
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Xinqiao Hospital of Chongqing
Impacted Fetal Head, Full Dilatation Caesarean Section
Lifting the Impacted Fetal Head; the Fetal Pillow and Tydeman Tube Trial
A single centre prospective observational comparison trial to compare the Tydeman Tube and Fetal Pillow, to aid delivery of the impacted fetal head at full dilatation caesarean section, and to evaluate the use of the Tydeman Tube…
- Trial name
- LIFT (NCT07372768)
- Testing
- Fetal Pillow, Tydeman Tube
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Postoperative Pain
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.
ECS is a very common procedure. A 1-year retrospective survey revealed a vast opioid consumption among the new mothers of approximately (mean±SD) 35±25 mg of oral morphine in the first 24 postoperative hours despite a multimodal…
- Trial name
- NCT03068260
- Testing
- Ropivacaine, Saline, Acetaminophen
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Adverse Effect
6% Hydroxyethyl Starch (130/0.4) Coload for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the ED50 and ED90 for an effective 6% Hydroxyethyl starch (130/0.4) coload infusion dose for postspinal anesthesia hypotension in patients undergoing cesarean section.
- Trial name
- NCT05475886
- Testing
- Hydroxyethyl starch 130/0.4
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Respiratory Depression
Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section
The study will examine whether there is a difference in the frequencies of respiratory depression among obese women receiving spinal anesthesia combined with opioids compared to women with normal BMI.
- Trial name
- NCT02819661
- Testing
- SOMNOTOUCH RESP, Caesarean section, Spinal anesthesia with intrathecal morphine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Ondansetron Lozenge, Postoperative Nausea and Vomiting
Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Caesarean Section
The aim of this study is to estimate the effect of preoperative ondansetron lozenge on prevention of postoperative nausea and vomiting in caesarean section.
- Conditions
- Ondansetron Lozenge, Postoperative Nausea and Vomiting, Caesarean Section
- Trial name
- NCT06254131
- Testing
- Ondansetron lozenge (Ondalenz ©), Ondansetron IV
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Hypotension
Association Between Preoperative Shock Index and Hypotension After Spinal Anaesthesia for Non- Elective Caesarean Section
This is a prospective observational study done in parturient planned for non-elective caesarean section. Association between shock index (HR/SBP) and post-spinal hypotension in parturient undergoing non-elective caesarean section…
- Trial name
- NCT04692870
- Where
- Nepal
- Volunteers
- 337 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Cesarean Section Pain, Diclofenac
Intramuscular Versus Rectal Diclofenac for Pain Relief After Cesarean Section in Women
The goal of this clinical study is to find out which way of giving diclofenac sodium provides better pain relief after a planned cesarean section: an injection into the muscle or a suppository given through the rectum.
- Conditions
- Cesarean Section Pain, Diclofenac, Suppository, Postoperative Pain
- Trial name
- NCT07379762
- Testing
- Diclofenac 75mg, Diclofenac 50mg
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Patient Reported Outcome Measures, Quality of Recovery
Translation and Validation of the Turkish Version of the ObsQoR-11 Questionnaire
Ciechanowicz et al. developed and validated a postpartum recovery score for women with a caesarean section: the ObsQoR-11. The psychometric validation of the ObsQoR-11 confirms its reliability, its response to change, its…
- Conditions
- Patient Reported Outcome Measures, Quality of Recovery, Cesarean Section, General Anesthesia
- Trial name
- ObsQoR-11T (NCT04744311)
- Testing
- ObsQoR-11T Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Failure of Cervical Dilatation, Complications; Cesarean Section
Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial
The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity
- Conditions
- Failure of Cervical Dilatation, Complications; Cesarean Section, Wound Infection,, External Causes of Morbidity and Mortality
- Trial name
- NCT01954719
- Testing
- cervix dilated after surgery, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Surgical Site Infection
Artificial Intelligence-Based Educational Guide
The study aimed to evaluate the effectiveness of an artificial intelligence-based educational guide to prevent surgical site infection among women delivering via cesarean section.
- Trial name
- AI/SSI (NCT07438314)
- Testing
- Artificial Intelligence-Based educational guide
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University
Cesarean Section, Post Operative Pain
ESPB vs Intrathecal Morphine for Assessements of Quality of Recovery After Cesarean Section
Cesarean section is a surgical procedure that involves significant pain, which is managed through a multimodal pharmacological approach.The primary objective of the study is to evaluate the quality of hospitalization after…
- Trial name
- BELLMERE (NCT07202416)
- Testing
- Erector spinae plane block, Intrathecal morphine
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- AUSL Romagna Rimini
Caesarean Section
Effect of Tramadol in Prevention of Postpartum Depression
The incidence of postpartum depression in Europe and the United States is about 10%, while in China the incidence rate of 15.7-39.8%.
- Trial name
- ETPPD (NCT03309163)
- Testing
- Tramadol, Hydromorphone, Ropivacaine (Epidural analgesia)
- Where
- China
- Volunteers
- 1,230 people
- Sponsor
- Xinqiao Hospital of Chongqing
Quality of Recovery, Caesarean Section
Validation of an Obstetric QoR Score and to Establish Its MCID.
The ObsQoR-11 is an 11-item survey that was recently developed to evaluate recovery after caesarean section. This has been shown to be valid, feasible, reliable and responsive to changes in health status.
- Trial name
- NCT03711552
- Testing
- ObsQoR-11, QoR-15
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Coombe Women and Infants University Hospital
Hypotension
Reduction in Spinal-induced Hypotension With Ondansetron in Parturients Undergoing Caesarean Section
Subarachnoid block is the preferred method of anaesthesia for caesarean section, but is associated with hypotension and bradycardia, which may be deleterious to both parturient and baby.
- Trial name
- NCT02913768
- Testing
- Ondansetron, Normal saline
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University