Clinical trials: Caesarean Delivery
Postpartum Hemorrhage
Randomization of Oxytocin, Oxytocin+Intrauterine Misoprostol and Carbetocin During C-section
Postpartum haemorrhage (PPH) remains an important cause of maternal morbidity and mortality and it accounts for approximately 25% of all deaths worldwide.
- Trial name
- NCT05083910
- Testing
- I.V Oxytocin administration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Drying Time
Chlorhexidine Drying Time
Before a patient gets a spinal/epidural, their lower back is cleaned with an antiseptic solution diluted in alcohol called ChloraPrep. ChloraPrep must completely dry before starting the anesthetic procedure.
- Trial name
- Chlorhexidine (NCT02095535)
- Testing
- Chlorhexidine gluconate
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pregnancy Related, Cesarean Delivery Affecting Fetus
Effects of Preoperative Oral Carbohydrate Loading on Maternal Thiol-disulfide Homeostasis
The primary aim of this randomised control trial is to assess the impact of pre-operative carbohydrate loading on thiol disulfide homeostasis when compared to standard care in elective cesarean section.
- Conditions
- Pregnancy Related, Cesarean Delivery Affecting Fetus, Fetus Fetus
- Trial name
- NCT05494268
- Testing
- Carbohydrate
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Postnatal Pulmonary Adaptation, Cesarean Section
Inhaled Salbutamol in Elective Caesarean Section
The lungs of the fetus are filled with fluid and it is essential that fetal lung fluid is cleared at birth. This process is mediated through the activation of airway epithelial sodium channels (ENaC).
- Trial name
- SAISTY (NCT01978418)
- Testing
- salbutamol
- Where
- Finland
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sture Andersson
Anesthesia, Cesarean Section Complications
Comparative Study Among Different Doses of Ephedrine During Elective Cesarean Section Under Subarachnoid Block.
compare the time of second hypotension after administration of three different doses of ephedrine 5,10,15 mg
- Conditions
- Anesthesia, Cesarean Section Complications, Subarachnoid Block
- Trial name
- NCT05993182
- Testing
- Ephedrine 5mg, Ephedrine 10mg, Ephedrine 15mg
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Aswan University
High Risk Pregnancy, Healing Surgical Wounds
Efficiency of Autologous Amniotic Fluid Injection in the Healing of Cesarean Section Scar in High-Risk Population
The goal of this randomized controlled trial is to investigate the effect of injection of autologous amniotic fluid in the healing of the scar of cesarean section among high-risk population.
- Trial name
- NCT06531356
- Testing
- autologous amniotic fluid, No amniotic fluid injected in skin edges
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Kasr El Aini Hospital
Magnetic Resonance Imaging, Hysteroscopy
Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
Cesarean section scar defects (CSDs) are one of the long-term complications following cesarean section. They can be detected by transvaginal sonography, hysterosalpingography, sonohysterography and magnetic resonance imaging…
- Trial name
- CSD (NCT05858931)
- Testing
- vaginal repair
- Where
- China
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Anesthesia, Spinal, Cesarean Section
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
- Conditions
- Anesthesia, Spinal, Cesarean Section, Echocardiography, Cardiac Output
- Trial name
- NCT05269537
- Testing
- Transthoracic Echocardiography, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Spinal Anaesthesia Induced Hypotension
Role of Ondansetron in Spinal Anaesthesia Induced Hypotension
The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.
- Trial name
- NCT06727201
- Testing
- Ondansetron (Zofran)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications, Scar Niche
A Two-Layered Simple Interrupted Myometrial Suturing Reduces Uterine Niche Formation After Primary Cesarean Section
The purpose of the study is to determine whether two-layered simple interrupted myometrial suturing is superior to double-layered continuous suturing for the prevention of uterine niche formation after primary cesarean section.
- Conditions
- Cesarean Section Complications, Scar Niche, Myometrial Remodeling, Suture Techniques
- Trial name
- NCT07229222
- Testing
- Primary Cesarean Section with two-layered simple interrupted suturing of the myometrium, Primary Cesarean Section with double-layered continuous suturing of the myometrium, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 380 people
- Sponsor
- Benha University
Breastfeeding, Motivation
Motivational Interviewing-Based Breastfeeding Education
The general purpose of this project is; to evaluate effect of motivational interviewing-based breastfeeding education on breastfeeding motivation, breastfeeding success and breastfeeding self-efficacy perception of primiparous…
- Conditions
- Breastfeeding, Motivation, Success, Self-Efficacy
- Trial name
- NCT05562245
- Testing
- Motivational Interviewing-Based Breastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cesarean Wound Repair
Extra - Abdominal Versus Intra - Abdominal Repair of the Uterine Incision at Cesarean Section
To evaluate the effects of extra-abdominal repair of the uterine incision compared to intra-abdominal repair, and to study is there superiority of one technique over the other in terms of primary outcomes - operative( up to 4…
- Trial name
- EKAM (NCT02373501)
- Testing
- Intra-abdominal repair, Extra-abdominal repair
- Where
- Israel
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Pre-eclampsia, Pre-Eclampsia, Severe
Prevalence of Blood Pressure Complications During Cesarean Section in Pre-eclamptic Patients (HOPE)
Preeclampsia (PE) is an obstetric placental vascular pathology with a prevalence of 2 to 5% of pregnant women. It is defined by learned societies by the association of high blood pressure (BP≥140/90mmHg) and proteinuria \&gt…
- Trial name
- HOPE (NCT06588023)
- Testing
- Observational study to evaluate professional practices
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cesarean Section
The Effect of Warm Local Anesthetic Solution on Epidural Anesthesia
The investigators are going to compare the onset and duration of nerve blockage with the use of pre-warmed (38°C) and room temperature (20°C) local anesthetic solutions (ropivacaine and fentanyl) on epidural anesthesia for…
- Trial name
- NCT03860402
- Testing
- Temperature
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Cesarean Section
Comparison of Barbed and Conventional Sutures in Adhesion Formation Following Cesarean Section
The aim of this randomized controlled trial is to determine whether the use of barbed sutures to close uterine incision at cesarean section is associated with more postoperative adhesions compared with conventional sutures or not.
- Trial name
- NCT03183362
- Testing
- Barbed suture ( STRATAFIX™ ), Conventional suture (VICRYL™)
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Cesarean Section
The Timing of Prophylactic Antibiotics in Cesarean Section and the Risk of Post-operative Febrile Morbidity
The purpose of this study is to determine whether the timing of prophylactic antibiotic administration for cesarean section (immediate preoperative versus intraoperative administration) impacts the rate of postoperative febrile…
- Trial name
- NCT00133029
- Testing
- Timing of prophylactic antibiotic administration
- Where
- United States
- Sponsor
- University of Pennsylvania
Cesarean Section Pain, Diclofenac
Intramuscular Versus Rectal Diclofenac for Pain Relief After Cesarean Section in Women
The goal of this clinical study is to find out which way of giving diclofenac sodium provides better pain relief after a planned cesarean section: an injection into the muscle or a suppository given through the rectum.
- Conditions
- Cesarean Section Pain, Diclofenac, Suppository, Postoperative Pain
- Trial name
- NCT07379762
- Testing
- Diclofenac 75mg, Diclofenac 50mg
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- CMH Multan Institute of Medical Sciences
Postoperative Pain
Postoperative Analgesia in Cesarean Delivery
İn this study, planned to compare the post-operative analgesic efficacy of Ilioinguinal iliohypogastric (II-IH) nerve block and Quadratus lumborum III Block in elective cesarean section operations.
- Trial name
- NCT06010602
- Testing
- Quadratus lumborum block, İlioinguinal-İliohipogastric nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pruritus
Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Neuraxial anesthesia, which includes epidural anesthesia and intrathecal anesthesia, is a frequent anesthetic approach for caesarean delivery and other lower abdominal and lower limb anesthetic procedures.
- Trial name
- NCT03483870
- Testing
- Morphine Sulfate, Granisetron
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
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