Clinical trials: Caesarean Delivery
Cesarean Delivery
Tap Block and Cesarean Delivery: Efficacy and Consumption of Postoperative Drugs
The purpose of this study is to determine the efficacy of Tap block after cesarean delivery as a component of multimodal analgesia and evaluation of postoperative drugs consumption.
- Trial name
- TAPFANS (NCT02801968)
- Testing
- Tap block, intravenous analgesia
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- S. Anna Hospital
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Maternal Anxiety, Cesarean Delivery
Restrained vs Gripping String Techniques in Patients Undergoing Cesarean Delivery
This randomized controlled trial will compare two upper-extremity restraint techniques in patients undergoing elective cesarean delivery under neuraxial anesthesia.
- Trial name
- NCT07772219
- Testing
- Standard Forearm Restraint, Wrist-Level Gripping Restraint
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- Ohio State University
Anesthesia, Spinal, Cesarean Section
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
- Conditions
- Anesthesia, Spinal, Cesarean Section, Echocardiography, Cardiac Output
- Trial name
- NCT05269537
- Testing
- Transthoracic Echocardiography, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Preterm Labor
The Cervical Length and Thickness of Cesarean Section Scar With Preterm Labor
Although the Cesarean section is one of the most common obstetric operations around the world, the World Health Organization recognizes that where cesarean rates are higher than 10%, there is no increase in beneficial maternal…
- Trial name
- NCT04554745
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Assiut University
Post Partum Hemorrhage
Prophylactic Regimen of Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative for Primary Prevention of Postpartum Hemorrhage in Intrapartum Cesarean Section Versus Intravenous Carbetocin Alone
While Carbetocin is effective in reducing PPH, the combination of oxytocin, Tranexamic acid, and Ergot derivatives may offer additional benefits in high-risk populations.
- Trial name
- NCT07318467
- Testing
- Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative, Intravenous Carbetocin alone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Delivery, Cesarean Delivery
Comparison of Inflammatory Responses Subsequent to Different Cesarean Section Techniques
In this study, the investigators aimed to find out whether there are any differences in inflammatory reactions occured subsequent to two different cesarean delivery techniques; modified Misgav-Ladach vs Pfannenstiel-Kerr…
- Conditions
- Delivery, Cesarean Delivery, Inflammation
- Trial name
- C/S (NCT02976311)
- Testing
- cesarean section(C/S) via the modified Misgav-Ladach technique, cesarean section via the Pfannenstiel-Kerr technique
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Surgical Site Infection (SSI)
Skin Adhesive Plus Intra-cuticular Suture Versus Suture Alone for Cesarean Skin Closure
The goal of this randomized control trial is to compare two skin closure techniques after cesarean section. Both techniques are currently in wide use but no comparison between the two was reasserted yet.
- Trial name
- NCT07483411
- Testing
- Dermabond
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Doron Kabiri
Postpartum Hemorrhage, Delivery Complication
Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the global leading cause of maternal death, with 20-30% of maternal deaths in Thailand linked to hemorrhage.
- Conditions
- Postpartum Hemorrhage, Delivery Complication, Cesarean Section Complications, Perinatal Problems
- Trial name
- NCT07278037
- Testing
- Tranexamic acid
- Where
- Thailand
- Volunteers
- 648 people
- Sponsor
- Mahidol University
Postoperative Pain
Acupuncture for Pain Control After Elective Caesarean Section
The study entitled "Acupuncture vs. placebo acupuncture and vs. standard therapy for pain control after elective caesarian section - a randomized controlled trial" aims to investigate whether acupuncture with indwelling fixed…
- Trial name
- ACUSEC (NCT02364167)
- Testing
- Standard therapy, Verum acupuncture
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Medicine Greifswald
Cicatrix
Perinatal Tissue Mesenchyme Stem Cells in the Treatment for Caesarean Section Scars
The study is to investigate the efficacy and safety of perinatal tissue mesenchyme stem cells treatment on the appearance of a caesarean scar as compared to a similar untreated scar.
- Trial name
- NCT02772289
- Testing
- Mesenchyme Stem Cells low-dose group, Mesenchyme Stem Cells high-dose group
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Method of Tubal Ligation at the Time of Cesarean Section
Standard Tubal Ligation Versus Salpingectomy for Sterilization at the Time of Cesarean Delivery
The objective of this study is to evaluate the feasibility and safety of salpingectomy versus standard tubal ligation in women undergoing surgical sterilization at the time of a planned cesarean delivery.
- Trial name
- NCT03028623
- Testing
- Salpingectomy, Tubal ligation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hypotension Drug-Induced
Different Preloads for Prevention of Hypotension in Patients Undergoing Elective CS Under Intrathecal Anesthesia
The aim of this study was to compare between crystalloid versus crystalloid and colloid combination preloads for prevention of hypotension following intrathecal anaesthesia in patients undergoing elective Caesarean section.
- Trial name
- NCT03465943
- Testing
- Ringer, Voluven
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section
Pre-operative Ultrasonographic Evaluation of the Internal Jugular Vein Collapsibility Index and Inferior Vena Cava Collapsibility Index to Predict Post Spinal Hypotension in Pregnant Women Undergoing Caesarean Section
Postspinal hypotension (PSH) is common in obstetric anesthesia practice, with an incidence of up to 71 %. PSH can occur precipitously and, if severe, can result in both maternal and fetal/neonatal adverse events.
- Trial name
- NCT04519996
- Testing
- US Internal Jugular Vein Collapsibility Index measurment, US Inferior Vena Cava Collapsibility Index measurment
- Volunteers
- 55 people
- Sponsor
- Tanta University
Hemodynamic Instability
Effect of Intravenous Ketamine Infusion for Hemodynamic Stability in Patients Undergoing Caesarean Delivery.
Hypotension is the most frequent side effect of intrathecal anesthesia, with a found incidence of more than 80%. With a frequency of between 40% and 60% in patients undergoing surgery, Perioperative shivering is a serious…
- Trial name
- NCT05865080
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cesarean Section Complications
Assessment of the Impact of Soft Tissue Mobilization on the Scar in Patients After Cesarean Section
The aim of the study is to assess the impact of soft tissue mobilization on the scar in patients after cesarean section. An additional aim is to assess the relationship between the initial stiffness and elasticity of the scar and…
- Trial name
- NCT06446258
- Testing
- Manual therapy (myofascial release, soft tissue mobilization)
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Cesarean Delivery
A Retrospective Comparison of Neonatal Acid-base Status After CD Before January, 2015 and After January, 2016
The objective is to retrospectively gather peri-operative data on neonatal outcomes, primarily neonatal acid-base status, based on umbilical cord gas analysis, for the 23 months preceding and 23 months following the conduct of…
- Trial name
- NCT03455660
- Testing
- no intervention
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Columbia University
Post Operative Pain
Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section
comparing analgesic efficacy of different nerve blocks on post operative cesarean sections.
- Trial name
- NCT06088420
- Testing
- Intrathcal Morphine Group, Quadratus Lumborum nerve block(QL) group, Erector Spinae nerve block (ESP)group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
Newborn Pain, Newborn Stress
Effect of Nesting During Intramuscular Injection on Pain, Stress, and Breastfeeding Success in Cesarean-Born Term Newborns
This randomized controlled trial aims to evaluate the effect of nesting during the first intramuscular injection on pain, stress level, physiological parameters, settling time, and breastfeeding success in healthy term newborns…
- Conditions
- Newborn Pain, Newborn Stress, Breastfeeding Success in Newborns
- Trial name
- NESTING (NCT07748520)
- Testing
- Nesting
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pain
Does Intraperitoneal Instillation of Lidocaine at Cesarean Delivery Improve Postoperative Analgesia?
The instillation of local anesthetic into the peritoneum has been found to be safe and effective in reducing postoperative pain and morphine consumption after abdominal surgery.
- Trial name
- NCT02264795
- Testing
- Lidocaine
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital