Clinical trials: Caffeine; Sleep Disorder
Sleep Deprivation, Performance
Impact of Sleep Deprivation and Caffeine in Medical Professionals
While the negative impact of sleep deprivation on cognitive processing and the partial reversal of this phenomenon by caffeine are well known, the types of cognitive processing previously studied have been limited to simple…
- Trial name
- NCT04273841
- Testing
- Military Energy Gum
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Drowsiness, Sleep Deprivation
TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE ©," AMONG COLLEGE STUDENTS
The goal of this randomized controlled educational study is to learn whether a structured, theory-based program can help reduce drowsy driving among college students (18 years and older) in Nevada.
- Conditions
- Drowsiness, Sleep Deprivation, Fatigue
- Trial name
- NCT07434921
- Testing
- MTM Theory based intervention, Standard AAA Knowledge based
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Apnea of Prematurity
Caffeine for Apnea of Prematurity-Sleep (CAP-S) Study
Apnea of prematurity is a common condition that is usually treated with methylxanthines. Methylxanthines are adenosine receptor blockers that have powerful influences on the central nervous system.
- Trial name
- CAP-S (NCT01020357)
- Testing
- Caffeine citrate injection
- Where
- 4 sites in Australia, Canada
- Volunteers
- 201 people
- Sponsor
- McMaster University
Heart Rate, Sleep Habit
EaseAlert: Tactile Firefighter Alerting System
The purpose of this research is to test a commercially viable Fire Fighter Altering System (FFAS) comprised of proprietary wearables and optional bed shakers called BunkAlerts; collectively "personal alerting devices" as an…
- Conditions
- Heart Rate, Sleep Habit, Sleep
- Trial name
- NCT05641194
- Testing
- Legacy Alerting System, Intervention 2: EaseAlert Standalone
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University
Caffeine, Insufficient Sleep
Consequences of Caffeine Intake in Sleep Restricted Teenagers
The goal of this clinical trial is to systematically investigate two prominent factors in teenagers' daily life: Caffeine and sleep restriction (SR) and their combined influence on sleep, cognition, and behavior in healthy…
- Trial name
- NCT05790161
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Psychiatric Hospital of the University of Basel
Shift Work
Effects of Operational Naps on Blood Pressure and Performance Among Night Shift Workers
Night shift work schedules disrupt sleep and have a negative impact on cardiovascular health. Most who work in public safety occupations and in healthcare work night shifts.
- Trial name
- EONN (NCT07217769)
- Testing
- No-nap, 15-min nap, 30-min nap
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sleep, Mood
A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products
This is a virtual, single-arm clinical trial that will last 12 weeks. Participants will trial three different products, each for 4 weeks.
- Conditions
- Sleep, Mood, Caffeine Withdrawal, Anxiety
- Trial name
- NCT06146517
- Testing
- Clevr Sleeptime, Clevr Matcha, Clevr Chai
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Clevr Blends
Parkinson's Disease, Excessive Daytime Somnolence
Caffeine for Excessive Daytime Somnolence in Parkinson's Disease
Many patients with Parkinson's disease (PD) have sleep problems, including excessive sleepiness during the day. This is probably due to degeneration of sleep-regulating areas in the brain.
- Trial name
- NCT00459420
- Testing
- Caffeine 100-200 mg BID
- Where
- 2 sites in Canada
- Volunteers
- 58 people
- Sponsor
- Ron Postuma
Sleep, Caffeine
Protocol PERCAF 2018
In this multicentric controlled study, we aims to evaluate effect of caffeine on mental performances during a sleep deprivation protocol. Genetic polymorphisms are considered as a covariable.
- Conditions
- Sleep, Caffeine, Polymorphism
- Trial name
- PERCAF (NCT03859882)
- Testing
- Sleep deprivation
- Where
- 2 sites in France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Polymorphism, Sleep Disorder
Polymorphisms, Caffeine and Sleep Disorders
Screening of a population of volunteer workers recruited on the occasion of their occupational health visit, within the Ministry of Defense and civil enterprises.
- Conditions
- Polymorphism, Sleep Disorder, Coffee-Workers' Disease
- Trial name
- SOCAF (NCT03855774)
- Testing
- Polymorphisms
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Anesthesia
MAPD: Modifiable Factors Affecting Propofol Dosing
The investigators aim to understand the effect of a caffeine intake, sleep habits, anxiety about surgery, alcohol intake and smoking status upon the dose of the anaesthetic drug, propofol, required for anaesthetic induction.
- Trial name
- NCT03453099
- Testing
- Preoperative Questionnaires, Postoperative Subjective Pain Scores
- Where
- United Kingdom
- Volunteers
- 91 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Caffeine Dependence, Anxiety
Remote Guided Caffeine Reduction
The purpose of this online research study is to determine whether or not a gradual caffeine reduction program developed at Johns Hopkins can help people reduce their caffeine use.
- Conditions
- Caffeine Dependence, Anxiety, Sleep Disturbance, Gastrointestinal Dysfunction
- Trial name
- NCT04560595
- Testing
- Caffeine Reduction Manual
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Volunteers, Caffeine
Caffeine Dose: Performance and Recovery
The goal of this clinical trial is to learn how different doses of caffeine taken in the evening affect rowing performance, sleep quality, and daytime alertness in trained male university rowers.
- Conditions
- Healthy Volunteers, Caffeine, Sleep Quality
- Trial name
- NCT07090421
- Testing
- Cellulose Powder, Caffeine 3 mg/kg Oral Powder, Caffeine 6 mg/kg Oral Powder
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ulaç Can YILDIRIM
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Caffeine, Sleep Deprivation
Real-Time Caffeine Optimization During Total Sleep Deprivation
Sleep deprivation (SD) has a powerful degrading effect on cognitive performance, particularly psychomotor vigilance (PV) and reaction time. Caffeine is well known to be an effective countermeasure to the effects of SD.
- Conditions
- Caffeine, Sleep Deprivation, Shift-Work Related Sleep Disturbance
- Trial name
- NCT04399083
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Narcolepsy
The Effect of Caffeine on the Narcoleptic Patients
Caffeine may be playing a beneficial role in patients with narcolepsy. However, the relationship between caffeine and its effects on narcoleptic patients has not been examined, and it is also unclear whether caffeine provides a…
- Trial name
- NCT02832336
- Testing
- Vivarin, Fiber
- Where
- Saudi Arabia
- Volunteers
- 16 people
- Sponsor
- King Saud University
Sleep Deprivation, Caffeine
Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)
This clinical trial will be a comparison between personalized recommended caffeine dosing regimen versus the standard recommended caffeine dosing regimen for sustaining performance during sleep deprivation and minimizing side…
- Trial name
- 2B-2 (NCT05588934)
- Testing
- Caffeine Gum
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
The aim of this study is to evaluate whether a smaller dose of caffeine sodium benzoate 10 mg/kg IV is as effective as 20 mg/kg IV in decreasing the number of children who develop post extubation adverse upper airway respiratory…
- Trial name
- NCT01349205
- Testing
- Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Atrial Fibrillation, Atrial Flutter
Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring
A prospective cohort study to evaluate the association between various triggers encountered in daily life and induction of atrial arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia and premature atrial…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- TriggersAF (NCT05526170)
- Testing
- Devices for long-term monitoring of objective and subjective parameters of the body
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Vilnius University
Neurobehavioral Manifestations, Drug Related Sleep Disturbance
Acute and Residual Effects of Caffeinated Beer
The aim of this study is to develop information about the acute and residual effects of a new product being targeted to young adults.
- Conditions
- Neurobehavioral Manifestations, Drug Related Sleep Disturbance, Alcohol Intoxication
- Trial name
- NCT00515294
- Testing
- Caffeinated Alcoholic Beer, Non-Caffeinated Alcoholic Beer, Caffeinated Non-Alcoholic Beer
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University