Clinical trials: Caffeine-Related Disorders
Athletic Performance, Caffeine
Caffeine and Wrestling Performance in Male Wrestlers of Different Weight Classes: A Randomized Crossover Trial
Caffeine is commonly used by athletes to improve performance, but not everyone responds to it in the same way. In weight-class sports like wrestling, athletes are grouped by body weight.
- Conditions
- Athletic Performance, Caffeine, Wrestling
- Trial name
- CAFF-WREST (NCT07889661)
- Testing
- Caffeine
- Where
- Iran
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Abadan Branch
Caffeine, Biomechanics
Effects of Caffeine Ingestion on the Biomechanics of Healthy Young Subjects
Caffeine is one of the few supplements that have enough scientific evidence to state that can notably improve performance, as different remarkable organizations in the sports nutrition context have classified it as an ergogenic…
- Conditions
- Caffeine, Biomechanics, Fatigue, Injuries
- Trial name
- NCT06039358
- Testing
- Caffeine., Cellulose.
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Obsessive-Compulsive Disorder
Dextro-Amphetamine Versus Caffeine in Treatment-resistant OCD
The study hypothesis is that dextro-amphetamine (d-amphetamine) will be safe and effective when used to augment treatment for Obsessive-Compulsive Disorder (OCD), and that tolerance (loss of therapeutic effect) to the medication…
- Trial name
- NCT00363298
- Testing
- dextro-amphetamine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Stanford University
Caffeine
Direct Effect of Caffeine on Diaphragmatic Muscles
The mechanism of methylxanthines is thought to increase chemoreceptor responsiveness to CO2 in central nervous system. Besides, effect of methylxanthines on diaphragmatic contractility has also been found in experimental studies.
- Trial name
- NCT04483492
- Testing
- Caffeine citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Hacettepe University
Dancesport Performance
Effects of Combined Rhodiola Rosea and Caffeine Supplementation on Dancesport Performance
This study evaluates the effects of caffeine, Rhodiola rosea, and their combined supplementation on dancesport-specific performance in male collegiate dancesport athletes.
- Trial name
- RHO-CAF-DanceS (NCT07690085)
- Testing
- Caffeine, Rhodiola Rosea Capsules, Standardized cowboy-dance-specific training program
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
CYP1A2 Polymorphism, Caffeine and Resistance Exercise
Caffeine, CYPA12 and Resistance Exercise
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance.
- Trial name
- NCT06610110
- Testing
- Caffeine
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alberto Pérez-López
Caffeine, Placebo
Caffeinated Chewing Gum on Special Forces Performance
The purpose of this project is to investigate the effects of caffeine chewing gum on the cognitive functions and special operations capabilities of special forces.
- Trial name
- NCT06638372
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Healty Volunteers
To Determine the Effect of KP-001 on Rosuvastatin, Caffeine PK and the Effect of Fluvoxamine on KP-001 PK in Volunteers
Part 1 will evaluate the effects of KP-001 as an inhibitor of BCRP on the PK of rosuvastatin. In the Treatment Period 1, a single dose of rosuvastatin will be administered.
- Trial name
- NCT06821698
- Testing
- KP-001, Rosuvastatin calcium10mg, Caffeine citrate
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kaken Pharmaceutical
Type 2 Diabetes
The Acute Effects of Coffee on Glucose Metabolism
The purpose of this study was to determine the acute effects of decaffeinated coffee, caffeinated coffee and caffeine on glucose metabolism in humans
- Trial name
- NCT00950898
- Testing
- decaff, caffcoff, caffeine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Brooklyn College of the City University of New York
Healthy
Relative Bioavailability of Ibuprofen From a Single Fixed Dose Combination Tablet of Ibuprofen and Caffeine Compared to Single Tablets of Ibuprofen and Ibuprofen Lysinate
To investigate the relative bioavailability of ibuprofen from a (FDC) film-coated tablet of ibuprofen and caffeine vs. a tablet of ibuprofen (Brufen®) and a tablet of ibuprofen lysinate (Nurofen Immedia®).
- Trial name
- NCT01879371
- Testing
- Ibuprofen+caffeine FDC, Ibuprofen (Nurofen Immedia®), Ibuprofen (Brufen®)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Caffeine, Placebo
Placebo Effects Investigated by Different Experimental Designs
This study aims to investigate the neurophysiological mechanisms of placebo perceived as caffeine during a motor task. Central and peripheral measures (i.e. electroencephalography and electromyography) will be assessed.
- Conditions
- Caffeine, Placebo, Baseline
- Trial name
- NCT04317157
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Neoplasm Metastasis
A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body
This study is known as a "drug interaction study" and is being done to see how abemaciclib may affect the blood levels of a drug mixture of commonly used drugs (caffeine, warfarin, dextromethorphan, and midazolam) when taken in…
- Trial name
- NCT02688088
- Testing
- Drug Cocktail, Abemaciclib
- Where
- 5 sites in United States
- Volunteers
- 48 people
- Sponsor
- Eli Lilly and Company
Diet Modification
Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism
The purpose of this study is to compare the effect of ingesting caffeine and mixed flavonoids (4 capsules, split between breakfast and lunch) on energy expenditure and fat oxidation in a metabolic chamber with 20 women…
- Trial name
- NCT03752125
- Testing
- Flavonoid, caffeine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Sodium, Caffeine
Study on Sodium and Caffeine in Children and Adolescents
This study will compare different methods (24 hour urine collection, evening and morning spots, and questionnaires) to measure the consumption of sodium and cafeine in children and adolescents.
- Trial name
- NCT02900261
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Alertness
Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage and Associated Mood and Physiological Effects
This study is designed to compare self-reported mood states for encapsulated caffeine compared to dose-matched free caffeine, when consumed as a ready-to-drink beverage in healthy subjects.
- Trial name
- NCT05096780
- Testing
- Flavored caffeinated beverage
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Birth Weight
Effect of Caffeine on Fetal Growth
The purpose of this study is to determine whether caffeine has any effect on birth weight.
- Trial name
- NCT00131690
- Testing
- Nescafé Gold Blend (exposed), Nescafé Decaffeinated (controls)
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- The Danish Epdiemiology Science Centre
Energy, Focus
Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus
Research has shown that acute ingestion of Paraxanthine (1,7-dimethylxanthine, PXN) can enhance various markers of focus, including memory, reaction time, and attention in healthy adults.
- Conditions
- Energy, Focus, Caffeine Withdrawal
- Trial name
- NCT06117280
- Testing
- Paraxanthine 200 mg, Paraxanthine 300 mg
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Iovate Health Sciences International Inc
Renal Colic
Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic
This is a prospective, randomized, single-blind study. Patients included in the study after successful treatment of the acute attack were randomized upon discharge from the Emergency Department into three groups: oral…
- Trial name
- RC (NCT06345716)
- Testing
- paracétamol tramadol, Paracétamol cafeine
- Where
- Tunisia
- Volunteers
- 1,500 people
- Sponsor
- University of Monastir
Hypercapnia
Influence of Caffeine on Psychomotor Vigilance and Carbon Dioxide Tolerance During Graded Hypercapnia
The aim of this randomized, double-blind, placebo-controlled crossover trial is to determine the effects of caffeine vs. placebo on psychomotor vigilance and carbon dioxide tolerance during graded hypercapnia.
- Trial name
- C3F (NCT06636825)
- Testing
- Graded hypercapnia, Caffeine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine