Clinical trials: Caffeine-Related Disorders
Dietary Supplements, Heart Rate/Drug Effects
Caffeine and Sodium Citrate Ingestion
A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.
- Conditions
- Dietary Supplements, Heart Rate/Drug Effects, Lactic Acid/Metabolism, Physical Education and Training/Methods
- Trial name
- NCT01591226
- Testing
- Caffeine, Sodium Citrate, Mannitol
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Healthy
How Does Altering the Timing of Pre-exercise Low-dose Caffeine Ingestion Affect Endurance Exercise Performance
Investigate how manipulating the time between caffeine ingestion and exercise may alter exercise performance and cognition
- Trial name
- NCT02985606
- Testing
- Caffeine powder -60, Caffeine powder -30, Caffeine powder 0
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Supplementation, Sports
The Influence of Caffeine Supplementation on Specific Performance and Training Activities
The purpose of this study is to verify the effect of acute caffeine (CAF) and placebo (PLA) supplementation on physical capacity and discipline-specific exercise performance in athletes, in a randomised, double-blind…
- Trial name
- NCT03822663
- Testing
- Caffeine supplementation
- Where
- Poland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Polymorphism, Sleep Disorder
Polymorphisms, Caffeine and Sleep Disorders
Screening of a population of volunteer workers recruited on the occasion of their occupational health visit, within the Ministry of Defense and civil enterprises.
- Conditions
- Polymorphism, Sleep Disorder, Coffee-Workers' Disease
- Trial name
- SOCAF (NCT03855774)
- Testing
- Polymorphisms
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Apnea of Prematurity
MICropsampling for CAffeine in PREMature Newborns
Caffeine is one of the top five most prescribed drugs in neonatology. Caffeine has many beneficial impacts on preterm infants (cardiac, neurologic and pulmonary). One of these beneficial impacts is to prevent apnea.
- Trial name
- MICCAPREM (NCT07779915)
- Testing
- collection of an extra drop of capillary blood
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Limoges
Caffeine
Effects of Caffeine on EEG Theta/Beta Ratio and Cognitive Control
Cognitive control driven by the prefrontal cortex (PFC) of the brain is thought to be important for goal-directed control over stimulus-driven processes.
- Trial name
- NCT02940808
- Testing
- Caffeine (200mg)
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Positron Emission Tomography
Brain Nicotine Receptor Density in Veteran Smokers
Cigarette smoking is more prevalent among Veterans (27%) than the general U.S. population (21%). Smoking is common among people who use marijuana or caffeine heavily, and the use of menthol cigarettes is becoming increasingly…
- Trial name
- BNRDVS (NCT01721473)
- Testing
- positron emission tomography scan
- Where
- 2 sites in United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Anaerobic Performance Neuromuscular Performance Cognitive Performance
Low-Dose Caffeine and Taurine Effects on Performance
This study aims to investigate the effects of low-dose caffeine and taurine, administered separately and in combination, on anaerobic, neuromuscular, and cognitive performance.
- Trial name
- CATAP (NCT07466654)
- Testing
- Caffeine, taurine, Caffeine + Taurine
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara University
Terbinafine Adverse Reaction
Clinical Effect of Caffeine Consumption in Patients Taking Oral Terbinafine
The investigators hypothesize that there would be significant changes in blood pressure or heart rate in patients consuming caffeine while taking terbinafine.
- Trial name
- NCT05667246
- Testing
- Caffeinated Coffee, Decaffeinated Coffee
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pain
A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine
An efficacy study assessing analgesic effect of ibuprofen/caffeine in post-surgical dental pain.
- Trial name
- NCT02863575
- Testing
- Ibuprofen/Caffeine, Ibuprofen
- Where
- United States
- Volunteers
- 374 people
- Sponsor
- Pfizer
Healthy
The Effects of Caffeine on Human Spinal Motoneurons
This study evaluates the effects of orally ingested, commercially available, coffee (3 mg/kg of caffeine) on the excitability of human spinal motoneurons of the lower leg.
- Trial name
- NCT04891393
- Testing
- Coffee, Decaffeinated coffee
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Temple University
Healthy
Effects of a Multi-Ingredient Pre-Workout Supplement on Energy Expenditure During Running
The primary purpose of this study was to examine the acute effects of one versus two doses of a multi-ingredient pre-workout supplement on energy expenditure during moderate-intensity treadmill running.
- Trial name
- NCT04352998
- Testing
- One dose pre-workout condition, Two dose pre-workout condition
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Healthy
Effect of Caffeine Consumption on Protein Biomarkers and Cardiovascular Disease
Caffeine is one of the most widely consumed substances worldwide. This study looks to test and measure the changes in different biomarkers in the blood before and after having caffeine using capillary and venous blood sampling…
- Trial name
- NCT06359197
- Testing
- Caffeine Pill, TASSO+ Device, Finger prick and collection on Whatman Protein 903 Saver Cards
- Where
- 3 sites in Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Improves Daytime Energy Levels, Reduces Afternoon Energy Crashes and Midday Fatigue
A Clinical Trial to Evaluate the Effects of Adrenal Adapt on Sleep Quality, Daytime Energy, Stress Resilience, and Cognitive Performance.
This is a single-group, open-label, uncontrolled clinical trial designed to evaluate the effects of Adrenal Adapt, a commercially available dietary supplement, on sleep quality, daytime energy, stress resilience, and cognitive…
- Conditions
- Improves Daytime Energy Levels, Reduces Afternoon Energy Crashes and Midday Fatigue, Improves Overall Sleep Quality and Restorative Sleep, Helps People Fall Asleep Faster and Wake Less During the Night
- Trial name
- NCT07893561
- Testing
- Adrenal Adapt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bioligent
Placebo Effect
The Effect of Tablet Size on Cognitive Performance Caffeine
This study aims to assess if tablet size, due to placebo effect, alters participants' performance on cognitive tests after consuming caffeine.
- Trial name
- CaC (NCT03694886)
- Testing
- Caffeine Anhydrous with small sucrose pill, Caffeine Anhydrous with large sucrose pill
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overactive Bladder, Urinary Urgency
Fluids Affecting Bladder Urgency and Lower Urinary Symptoms
This study evaluates whether eliminating certain ingredients (caffeine, alcohol, artificial sweeteners, acidic juices) consumed in beverages reduces bladder symptoms of urinary frequency and urgency.
- Conditions
- Overactive Bladder, Urinary Urgency, Urinary Bladder, Overactive, Urinary Incontinence, Urge
- Trial name
- FABULUS (NCT03625492)
- Testing
- Reducing Potentially Irritating Beverages, Adopting the USDA Healthy Eating Habits
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Caffeine, Placebo
Caffeine & Bodybuilding Dehydration Ability
15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06431035
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Cardiovascular Injury
Synthetic and Natural Caffeine on Hemodynamic Parameters in Young, Healthy Volunteers
The purpose of this study determine the difference in hemodynamic effects of synthetic and natural caffeine consumption in healthy individuals through blood pressure (central and peripheral) assessment.
- Trial name
- NCT03495063
- Testing
- Natural Caffeine, Synthetic Caffeine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Cataract
Caffeine and Cataract After Pars Plana Vitrectomy
Assessment of cataract development in patients with regular caffeine consumption and those without caffeine consumption after pars plana vitrectomy.
- Trial name
- NCT06358664
- Testing
- Pars plana vitrectomy
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery