Clinical trials: Caffeine-Related Disorders
Asymptomatic Conditions
Effects of Caffeine and Coffee on Resting Metabolic Rate, Comparing Normal Weight Men to Obese Men
Background. The prevalence of obesity has increased in the last two decades. To maintain body weight energy expenditure (EE) should be equal to energy intake (EI).
- Trial name
- RMR (NCT02751840)
- Testing
- Caffeine, Coffee, Decaffeinated
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
HIV Infection, Healthy
The Effect of Milk Thistle on the Pharmacokinetics of Indinavir
Complementary and alternative medicines are widely used in the HIV-infected population. Recent data have shown serious drug interactions between certain complementary medicines and protease inhibitors.
- Trial name
- NCT00011635
- Testing
- Silymarin (milk thistle)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
EIMD Mechanisms Causing Force Loss
We have hypothesized: 1) Caffeine will increase maximal voluntary strength compared to placebo in undamaged muscle. 2) Caffeine will increase muscle activation compared to placebo in undamaged muscle.
- Trial name
- NCT02125643
- Testing
- Caffeine, Flour
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Exercise Performance
Effects of Beetroot Juice and Caffeinated Coffee on Exercise Performance in Recreationally Active Men
The goal of this clinical trial was to evaluate how acute intake of beetroot juice, caffeinated coffee, and their combination affected aerobic and anaerobic exercise performance in healthy recreationally active men.
- Trial name
- NCT07797062
- Testing
- Beetroot juice, Caffeinated Turkish Coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Healthy, Alcohol Drinking
Binge Drinking of Alcohol Mixed With Energy Drinks
The purpose of the study is to assess the relevance of gender in the acute effects (subjective, physiological and driving-related skills) observed after controlled administration of alcohol in a binge-drinking pattern mixed with…
- Trial name
- ENERGYBINGE (NCT04616859)
- Testing
- Alcohol and Energy Drink (AmED)
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
Exercise Performance Impairment, Cognitive Function Decline
Effects of Energy Drink on Repeated Sprint Performance and Cognitive Function in Athletes
Energy drinks are often used by athletes before competitions to enhance their performance. Recent research has pointed out that the performance effects of select ingredients have been studied individually but not in combination…
- Conditions
- Exercise Performance Impairment, Cognitive Function Decline, Fatigue
- Trial name
- NCT07104188
- Testing
- Caffeine, Energy Drink
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Huntington Disease
Is Caffeine an Environmental Modifier in Huntington's Disease?
The aim of the study is to establish if caffeine consumption is associated with the evolution of the disease in premanifest HD.
- Trial name
- CrEAM-HD (NCT03034122)
- Where
- 10 sites in France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Lille
Atrial Fibrillation
Prevention of Atrial Fibrillation Following Valvular Replacement With Cardiopulmonary Bypass: a Prospective, Randomized Clinical Study Comparing Oral Caffeine With Placebo
Atrial fibrillation remains a major cause of morbidity following cardiac surgery with cardiopulmonary bypass. Many mechanisms have been implicated.
- Trial name
- NCT01999829
- Testing
- citrate of caffeine
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Back Pain, Neck Pain
Ibuprofen/Caffeine Lower Back or Neck Pain Study
To assess the efficacy and safety of a 400 mg ibuprofen/100 mg caffeine tablet in comparison to a 400 mg ibuprofen tablet for the treatment of acute lower back or neck pain.
- Trial name
- NCT03003000
- Testing
- ibuprofen, caffeine
- Where
- 18 sites in Germany, Russia
- Volunteers
- 635 people
- Sponsor
- Boehringer Ingelheim
Pain
Ibuprofen Versus Ibuprofen Plus Caffeine in the Treatment of Migraine.
Primary Objective: To compare the treatment groups in the reduction of pain score by at least 30 mm on a visual pain scale (VAS) at 60 minutes after study medication intake, compared to the baseline score (obtained before the…
- Trial name
- NCT01426971
- Testing
- IBUPROFEN + CAFFEINE, IBUPROFEN
- Sponsor
- Sanofi
Intermittent Hypoxia
Intermittent Hypoxia and Caffeine in Infants Born Preterm
Intermittent Hypoxia and Caffeine in Infants Born Preterm (ICAF) Our proposal will address the critical question: is persisting intermittent hypoxia (IH) in preterm infants associated with biochemical, structural, or functional…
- Trial name
- ICAF (NCT03321734)
- Testing
- Caffeine
- Where
- 15 sites in United States
- Volunteers
- 170 people
- Sponsor
- Children's National Research Institute
Hypoxic Ischemic Encephalopathy (HIE)
Neonates With Hypoxic Ischemic Encephalopathy (HIE)
Assessment of the potential neuroprotective effect of magnesium sulphate and caffeine in treating asphyxiated newborns and improvement of the neurological outcome of Hypoxic Ischemic Encephalopathy in Assiut university hospital…
- Trial name
- NCT06694545
- Volunteers
- 72 people
- Sponsor
- Assiut University
Voice Disorders
Interaction of Caffeine and Hydration on Voice
The purpose of the study, Effects of Interaction of Caffeine and Hydration on Voice Performance, is to gather information about the effects of caffeine and hydration upon voice performance.
- Trial name
- NCT01435837
- Testing
- C2 (200mg of caffeine; 1/2 L of water), C3(200mg of caffeine; 1 L of water), C1 (200mg of caffeine, no water)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University Carbondale
Atrial Fibrillation, Atrial Flutter
Triggers and Risk Factors for Recurrence of Atrial Arrhythmias With the Use of Long-term Monitoring
A prospective cohort study to evaluate the association between various triggers encountered in daily life and induction of atrial arrhythmias (atrial fibrillation, atrial flutter, atrial tachycardia and premature atrial…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia, Atrial Tachycardia
- Trial name
- TriggersAF (NCT05526170)
- Testing
- Devices for long-term monitoring of objective and subjective parameters of the body
- Where
- Lithuania
- Volunteers
- 182 people
- Sponsor
- Vilnius University
Healthy
Evaluation of the Potential CYP1A2-mediated Drug Drug Interaction Safety, and Tolerability of ABX464
A two part, fixed-sequence, open-label crossover study to evaluate potential CYP1A2-mediated drug-drug interactions of ABX464 in healthy subjects using caffeine and fluvoxamine as probe drugs
- Trial name
- NCT05121714
- Testing
- Caffeine, ABX464, Fluvoxamine
- Where
- United Kingdom
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
Caffeine, Balance; Distorted
The Effect of Turkish Coffee on Postural Control and Hand-eye Coordination in Young Adults
Although the effects of different doses of caffeine on balance have been evaluated in various studies, the effects of low doses of caffeine ingested with Turkish coffee on postural control and hand-eye coordination remain…
- Conditions
- Caffeine, Balance; Distorted, Coordination and Balance Disturbances
- Trial name
- NCT06561113
- Testing
- Caffeine intake
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Volleyball Players, Performance
Caffeinated Gum Use and Volleyball Performance
This study examined the acute effects of caffeinated chewing gum on volleyball performance in trained female volleyball players.
- Trial name
- NCT07597265
- Testing
- Single-dose caffeinated gum, Partial-dose caffeinated gum
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ege University
Caffeine
Caffeine and Cerebrovascular Reactivity
Caffeine is the most commonly used stimulant drug with well documented effects on cerebral vascula-ture. Caffeine is known to non-specifically bind to adenosine receptors in the brain and to reduce resting blood flow while…
- Trial name
- NCT04730193
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Adenosine Metabolism
The Effect of Rosuvastatin on Adenosine Metabolism
The aim of this study is to show whether rosuvastatin influences adenosine metabolism. Therefore we will determine whether rosuvasatin increases dipyridamole-induced vasodilation by increased adenosine receptor stimulation.
- Trial name
- NCT00554138
- Testing
- rosuvastatin
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Arrhythmia
Arrhythmic Effects of Hight Dose Caffeine
Heart failure patients represent a group of individuals at higher risk for cardiac arrhythmias. There is a perception that caffeine consumption may represent an increase in this risk.
- Trial name
- NCT02045992
- Testing
- caffeine
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- Luis Eduardo Paim Rohde