Clinical trials: Caffeine-Related Disorders
Postdural Puncture Headache
Effect of Coffee on Postdural Puncture Headache After Cesarean Section
The purpose of this study is to investigate the effects of postoperative coffee consumption on postdural puncture headache (PDPH) and analgesic use in women undergoing cesarean section with spinal anesthesia.
- Trial name
- NCT07410741
- Testing
- Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Apnea of Prematurity
Caffeine for Apnea of Prematurity-Sleep (CAP-S) Study
Apnea of prematurity is a common condition that is usually treated with methylxanthines. Methylxanthines are adenosine receptor blockers that have powerful influences on the central nervous system.
- Trial name
- CAP-S (NCT01020357)
- Testing
- Caffeine citrate injection
- Where
- 4 sites in Australia, Canada
- Volunteers
- 201 people
- Sponsor
- McMaster University
Intermittent Claudication
Caffeine and Intermittent Claudication
The purpose of this study is to evaluate the change in Walking capacity after an intake of caffeine. The study design is cross-over and follow-up of 80 patients with leg pain caused by narrowing of their leg arteries, Peripheral…
- Trial name
- NCT00388128
- Testing
- Caffeine 6mg/kg
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Ischemia-Reperfusion Injury
Adenosine Receptors Influence Ischemia-Reperfusion Injury
Ischemic preconditioning is defined as the development of tolerance to ischemia-reperfusion injury by a previous short bout of ischemia resulting in a marked reduction in infarct size.
- Trial name
- NCT00184847
- Testing
- acetylcholine, twenty minutes of forearm ischemia, three 5-minute periods of forearm ischemia
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Obesity
B181 Metobes-III: Weight Loss Maintenance of a New Bioactive Compound (Metobes-Long)
To investigate the 5-hour acute effect on energy expenditure, substrate oxidation and ad libitum food intake after intake of the Metobes-compound (green tea extract, capsaicin, tyrosine, caffeine).
- Trial name
- NCT00302263
- Testing
- Metobes-compound
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Headache, Pregnancy Related
Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine
This is an open label randomized controlled trial evaluating response to bupivacaine occipital nerve block compared to Tylenol/Caffeine cocktail in treatment of pregnant patients seeking care of headache.
- Conditions
- Headache, Pregnancy Related, Occipital Nerve Block
- Trial name
- NCT03951649
- Testing
- Occipital Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Caffeine, Heart Rate Variability
Effect of Caffeine on Heart Rate Variability in Newborns
The aim of this study was to evaluate the impact of caffeine treatment, given either orally or intravenously, on heart rate variability in newborns.
- Conditions
- Caffeine, Heart Rate Variability, Apnoea of Newborn, Newborn
- Trial name
- NCT04869176
- Testing
- Electrocardiogram, Monitoring of vital functions, Caffeine Citrate 5 mg/kg
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University of Ljubljana
Healthy
Caffeine Intake and Additive Effects on Cognition
Caffeine is a methylxanthine commonly consumed by the population for their psychostimulant properties, and their intake when in moderate doses seem to produce positive effects on stress, mood and memory.
- Trial name
- Caffeine (NCT02647567)
- Testing
- Caffeine Intake
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Fatigue
"WakeUp" for Vigilance Following Lunch
This is a single center, double-blind, placebo and active controlled clinical trial comprised of a single drink of WakeUp beverage (in 3 doses) compared to Caffeine (100mg) and placebo given to health volunteers.
- Trial name
- NCT04685005
- Testing
- "Wake Up", Caffeine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Caffeine, Adaptation
The Turkish Version Of The Brief-Caffeine Expectancy Questionnaire
Caffeine is a psycho-active substance that is widely consumed in the world. It is seen that its widespread consumption is related to expectancies of consumption as well as cultural factors.
- Conditions
- Caffeine, Adaptation, Expectations, Language
- Trial name
- NCT06038903
- Testing
- caffeine consumption expectation
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eskisehir Technical University
Headache Disorders, Primary, Migraine With Aura
IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice
Headaches are a common medical problem that physicians frequently encounter in their practice. One of key findings of The Atlas of Headache Disorders prepared by World Health Organization (WHO) is: headache disorders, including…
- Conditions
- Headache Disorders, Primary, Migraine With Aura, Migraine Without Aura, Tension-Type Headache
- Trial name
- PRESTO (NCT02115269)
- Where
- 30 sites in Kazakhstan, Ukraine
- Volunteers
- 759 people
- Sponsor
- Abbott
Apnea of Prematurity, Intraventricular Hemorrhage
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Over the last 30 years the survival rates for babies born prematurely have improved greatly with research. As these babies grow up, we have found that many of the premature babies have learning and movement problems.
- Conditions
- Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
- Trial name
- NCT00809055
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Postoperative Ileus, Cesarean Section Complications
The Effect of Caffeine Ingestion in Prevention of Postoperative Ileus After Caesarean Section.
Many trials have been made to prevent paralytic ileus , including administration of prokinetic drugs , early resumption of feeding, gum chewing and adequate pain control.
- Conditions
- Postoperative Ileus, Cesarean Section Complications, Caffeine
- Trial name
- NCT03815877
- Testing
- Nescafe Gold ® coffee, Nescafe Gold DECAF® coffee
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy, Caffeine
Effects of Variations in Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverage variations in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07404254
- Testing
- Caffeinated, low sugar beverage, Caffeinated beverage, Control beverage
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Obesity
"Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat
This study compares four treatments to see which one causes the most weight loss, fat loss, loss of abdominal fat and improvement in blood tests like cholesterol.
- Trial name
- NCT00377975
- Testing
- Ephedrine, Pioglitazone, Caffeine
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Running Performance
Does a Caffeine Gum Improve 5 km Run Performance in a Competition/Field Setting?
The purpose of this study is to determine whether caffeine gum improves the performance of runners completing free timed mass participation 5 km runs in the United Kingdom (UK)
- Trial name
- NCT02473575
- Testing
- caffeine gum
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Migraine Headaches
Prochlorperazine Versus Acetaminophen, Aspirin, and Caffeine for the Treatment of Acute Migraine
The objective of this randomized, double blind study is to demonstrate that one dose oral "excedrin migraine" (acetaminophen, aspirin and caffeine) is not inferior when compared to one dose of intravenous prochlorperazine for the…
- Trial name
- Migraine (NCT01629329)
- Testing
- Aspirin, Acetaminophen, Caffeine pills, Prochlorperazine 10mg
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Albert Einstein Healthcare Network
Pain, Migraine
Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine
The main purpose of this study is to compare the efficacy and safety of aspirin, acetaminophen and caffeine (AAC) with sumatriptan and placebo in the acute treatment of migraine.
- Trial name
- NCT01248468
- Testing
- Aspirin, acetaminophen and caffeine, Sumatriptan
- Where
- 20 sites in United States
- Volunteers
- 752 people
- Sponsor
- Novartis
Molecular Imaging
Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
The primary objective of this study is to determine if exercise, fasting, or eating prior to the molecular breast imaging study will have an effect on the uptake of the tracer in the breast tissue.
- Trial name
- NCT01944215
- Testing
- Meal, Exercise, Sestamibi
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Caffeine and Resistance Exercise
Caffeine, Resistance Exercise and Muscle/Cerebral Oxygenation
Introduction: Several studies have evaluated and confirmed the ergogenic effects of acute caffeine intake on sports performance. However, the mechanism responsible for this ergogenic effect remains to be elucidated.
- Trial name
- CAF+RE+Oxy (NCT07001176)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alcala