Clinical trials: Caffeine-Related Disorders
Coronary Disease
The Impact of Caffeine on Brachial Endothelial Function in Healthy Subjects and in Patients With Ischemic Heart Disease
Prior work (Chris, M. et al, Clinical Science 2005; 109, 55-60) has demonstrated that drinking a cup of coffee (80-100 mg of caffeine) an hour before endothelium-dependent FMD (flow-mediated dilatation) of the brachial artery…
- Trial name
- NCT00564824
- Testing
- Caffeine
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fatigue, Tachycardia
Effect of Caffeine on Heart Function
The primary objective of this study is to assess the effect of an energy drink on ventricular repolarization as measured by the interval between the cardiac Q wave and the cardiac T wave (QT interval)obtained from the body…
- Trial name
- NCT02401776
- Testing
- Monster Energy Drink, Coffee
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Snoring
The Effect of Caffeine Reduction on Snoring and Quality of Life
Snoring is a problem for many people, often disturbing energy level, quality of sleep, and the relationship with a bed partner. Two observational studies that have indicated a relationship between the consumption of caffeine and…
- Trial name
- NCT00641810
- Testing
- Caffeine reduction
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Caffeine-Related Disorders
Validation of a 24-hour Caffeine Intake Recall
A 24-hour Caffeine Intake Recall (CIR-24) was developed to estimate caffeine consumption in the previous 24 hours, modeled after the Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24), using a brand-specific…
- Trial name
- NCT03292380
- Testing
- No intervention was included
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- University of Waterloo
Healthy
The Effect of Coffee on People with High Intensity Exercise and the Characteristics of Caffeine Metabolism
The purpose of this project is to explore the relationship between the effect of coffee on exercise performance and caffeine metabolism.
- Trial name
- NCT06712667
- Testing
- Caffeine content
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Caffeine, Teacrine, and Dynamine: Effects on Performance
The Effects of a Combination of TeaCrine®, Dynamine, and Caffeine in Law Enforcement
The purpose of this randomized, placebo-controlled, three-condition, double-blind, between-subjects clinical trial is to determine and compare the effects of the combination of TeaCrine®, Dynamine, and caffeine to a placebo and…
- Trial name
- NCT03937687
- Testing
- Caffeine+TeaCrine+Dynamine, Caffeine
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Caffeine, Affect
Motivational, Affective and Performance Effects of Caffeine Supplementation
The main objective of the study is to evaluate the influence of caffeine intake on participants' energetic arousal, affect, motivation to achieve a training goal, satisfaction with training, and the sense of agency during…
- Conditions
- Caffeine, Affect, Goals
- Trial name
- NCT06321861
- Testing
- Caffeine, No substance
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Caffeine and Resistance Training
Caffeine and Resistance Training in Older Adults
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance.
- Trial name
- NCT06618261
- Testing
- Caffeine + Resistance exercise
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Alberto Pérez-López
Caffeine
Does Caffeine Facilitate Human Reward Learning Behaviors?
"Learning from the rewards" is underlying the formulation of knowledge and habits in daily life. Caffeine is the most commonly used "psychoactive" substance that could change one's mind state by affecting the brain and nervous…
- Trial name
- ADoRe (NCT05325502)
- Testing
- caffeine, mannitol
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yu-Shiuan Lin
Atrial Fibrillation
Impact of Intravenous Caffeine on Atrial Electrical Properties and Potential Arrythmia Induction
This "How caffeine Induces Atrial Tachyarrhythmias" trial will be a multi-center, randomized, double-blinded trial of intravenous caffeine versus placebo among patients undergoing pulmonary vein isolation procedures for Atrial…
- Trial name
- NCT05464940
- Testing
- Intravenous caffeine
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
L-theanine
Theanine and Caffeine on Neurophysiology of Attention
L-theanine and caffeine are nutritional compounds that are naturally found in tea. Our recent findings using an EEG paradigm are consistent with the findings of others, indicating that intake of L-theanine and caffeine reduce the…
- Trial name
- THECNA (NCT02770105)
- Testing
- Theanine, Caffeine, Theanine-Caffeine Combination
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Dietary Supplements, Caffeine
Effect of Acute Caffeine and Beetroot Juice Intake on Strength, Power, and Muscular Endurance
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine and beetroot juice intake on sports performance.
- Conditions
- Dietary Supplements, Caffeine, Nitrates, Sports Performance
- Trial name
- CAF+BJ (NCT06596395)
- Testing
- Acute caffeine and beetroot juice, Acute caffeine, Acute beetroot juice
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Aerial Duel Performance in Soccer Players
Combined Caffeine and Rhodiola Rosea on Aerial Duel Performance in Soccer
This study will examine whether caffeine (CAF) and Rhodiola rosea (RHO) supplementation, taken alone or in combination, can improve explosive performance and soccer-specific aerial duel performance in trained male soccer players.
- Trial name
- CCRP-AD (NCT07458594)
- Testing
- Caffeine, Rhodiola rosea extract
- Where
- 2 sites in China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
NIRS, Tissue Oxygenation
CHECK-NIRS2D-Study
The study investigates how external, physiological, and behavioral factors influence the measurement of regional tissue oxygenation using two-dimensional near-infrared spectroscopy (NIRS) imaging in healthy volunteers.
- Conditions
- NIRS, Tissue Oxygenation, Microvascular Perfusion, Vascular Occlusion Test
- Trial name
- NCT07854431
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Pharmacokinetics
Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States
Pilot study designed to characterize the plasma caffeine pharmacokinetic profile of encapsulated caffeine when consumed in the fasted and fed states.
- Trial name
- NCT05266248
- Testing
- 250 mg encapsulated caffeine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Gastrointestinal Motility, Postoperative Pain
Effects of Mobilization and Caffeine After Cesarean
This study Maims to assess bowel motility, pain and psychological well-being in women in the post-cesarean period by mobilizing them early and encouraging them to consume coffee.
- Conditions
- Gastrointestinal Motility, Postoperative Pain, Psychological Well-Being
- Trial name
- NCT07369726
- Testing
- caffeine consumption, Decaffeinated coffee
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Healthy, Caffeine
Effects of Caffeinated Beverages on Well-being
This study will evaluate post-beverage subjective caffeine responses and physiological responses to caffeinated beverages in generally healthy adults.
- Conditions
- Healthy, Caffeine, Beverage Intake
- Trial name
- NCT07357818
- Testing
- Participants' typical caffeinated beverage, Test caffeinated beverage
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- GUAYAKI SUSTAINABLE RAINFOREST PRODUCTS, INC.
Migraine, Migraine Disease
Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals
Caffeine extracted from green tea to abort acute attack of Migraine
- Conditions
- Migraine, Migraine Disease, Migraine Headache, Migraine Headache, With or Without Aura
- Trial name
- NCT07022496
- Testing
- Caffeine (200 mg), triptans, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Healthy
Explore the Use of Cortical Oxygenation Measures in Nutrition Research
The current project aims to explore the use of cortical oxygenation measures obtained with functional Near Infrared Spectroscopy (fNIRS) in acute nutrition interventions with outcomes on cognition.
- Trial name
- Saga (NCT07191665)
- Testing
- Acute nutrition intervention
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Société des Produits Nestlé (SPN)