Clinical trials: Calcinosis Cutis
Calciphylaxis
SEAPORT 1: Study of INZ-701 in Adults With Hemodialysis-Dependent End-Stage Kidney Disease
This Phase 1, open-label, multicenter study evaluated the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of INZ-701 in adults with hemodialysis-dependent end-stage kidney disease (ESKD) and low plasma inorganic…
- Trial name
- SEAPORT 1 (NCT06283589)
- Testing
- INZ-701
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Inozyme Pharma
Systemic Sclerosis (SSc), Calcinosis Cutis
Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images
The main purpose of this study is to develop sensitive radiographic measurement techniques that can be used as outcome measures along with patient-reported outcome instruments in clinical trials of calcinosis cutis treatments…
- Trial name
- NCT07228429
- Testing
- Sodium Thiosulfate (STS), Sodium Thiosulfate Injection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Yale University
Systemic Sclerosis
Evaluation of Calcinosis in Systemic Sclerosis
Systemic sclerosis is a rare pathology characterized by fibrosis and vascular lesion with skin, pulmonary, digestive and cardiac localisation.
- Trial name
- CALCIDERMIS (NCT03340194)
- Testing
- Radiography, Veinous punction
- Where
- France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Lille
Dermatomyositis, Dermatomyositis With Calcinosis Cutis
Photoacoustic/Ultrasound Imaging in Patients of Dermatomyositis With Calcinosis Cutis: Characteristic Findings and Treatment Response Evaluation
Photoacoustic imaging (PAI) is an emerging biomedical modality that integrates the advantages of optical contrast and ultrasound imaging depth.
- Trial name
- NCT07037472
- Testing
- Multi-modal photoacoustic/ultrasonic (PA/US) imaging system, Drug treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Scleroderma, Calcinosis Cutis
Effectiveness of ESWT and PNF in Scleroderma With Calcinosis
Investigation of the effects of ESWT and PNF exercises added to ESWT on calcinosis in Ssc patients. Calcinosis cutis is a common, difficult-to-treat manifestation of systemic sclerosis associated with high morbidity.
- Trial name
- NCT05870852
- Testing
- Extracorporeal Shock Wave Therapy (ESWT), PNF
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Calcinosis Cutis
Efficacy of Intralesional Sodium Thiosulfate Versus Intralesional Saline for Dystrophic and Idiopathic Calcinosis Cutis
The purpose of our research is to compare the effectiveness of 125mg/50ml sodium thiosulfate (STS) solution to normal saline (0.9% sodium chloride) when injected intralesionally for the treatment of calcinosis cutis.
- Trial name
- NCT03639779
- Testing
- Sodium Thiosulfate, Saline Solution
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
CREST Syndrome, Calcinosis Cutis
Localized Effects of PBM and Exogenous NO on CREST Patients Calcinosis Cutis & Raynaud Phenomenon
Background CREST is an acronym for the cardinal clinical features of the syndrome (Calcinosis, Raynaud phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasia) and part of the heterogeneous group of sclerodermas.
- Conditions
- CREST Syndrome, Calcinosis Cutis, Raynaud Phenomenon
- Trial name
- NCT03972566
- Testing
- INOMAX
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- RoseLab Skin Optics Laboratory
Calcinosis Cutis
A Pilot Study to Evaluate Topical Sodium Thiosulfate Therapy for Calcinosis Cutis
Calcinosis cutis refers to a group of disorders characterized by calcium deposition in the skin (1). The disorders are classified according to etiology into the following types: dystrophic, metastatic, iatrogenic, and idiopathic…
- Trial name
- STS-CALC (NCT01918904)
- Testing
- Sodium thiosulfate
- Sponsor
- Loyola University
Calcinosis Cutis in Connective Tissue Disease
Calcinosis Cutis: Therapeutic Effects of Extracorporeal Shock Wave Therapy (ESWT)
Patients with calcinosis cutis due to connective tissue disease get a shock wave therapy. The shock wave therapy will be done in 3 sessions with one week interval.
- Trial name
- NCT01683500
- Testing
- shock wave therapy with Modulith SLK (Storz)
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- University of Zurich