Clinical trials: Calcium
Acute Renal Failure, Dialysis; Complications
New Protocol With Diluted Citrate in Continuous Techniques
The investigators designed a monitoring and control table of a citrate treatment on a specific monitor. This is the Baxter "Prismaflex" monitor, with 8.2 software version.
- Conditions
- Acute Renal Failure, Dialysis; Complications, Citrate Poisoning
- Trial name
- NCT04062812
- Testing
- the same citrate dosification in both types
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
MTA, Calcium Hydroxide
Influences of Different Temporary Cement on Retention Rate of Temporary Crowns
The aim of this study is through a randomized clinical trial, double blind, split-mouth, evaluate the success rate (retention rate and dental sensibility) of temporary dental crown cemented on vital teeth.
- Conditions
- MTA, Calcium Hydroxide, Dental Crown
- Trial name
- NCT03437629
- Testing
- Temporary cement based on Calcium Hydroxide, MTA temporary cement
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Uberlandia
Osteoporosis
The Interaction Between Calcium and Vitamin D Intake
We will study the relative importance of high calcium intake and vitamin D supplementation for calcium homeostasis, as determined by serum parathyroid hormone (PTH) and biochemical bone markers.
- Trial name
- PTH Modified (NCT00762775)
- Testing
- Calcium and vitamin D supplementation
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Head Neck Cancer
Calcium Electroporation for Head and Neck Cancer
In a phase I protocol to primarily investigate the safety of using calcium combined with electroporation on recurrent head and neck cancers.
- Trial name
- NCT03051269
- Testing
- Calcium chloride, Electroporation
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy
The Effect of Etelcalcetide on CKD-MBD
The proposed study will investigate the effects of etelcalcetide on the bone and blood-vessel health in patients with CKD-MBD. The investigators will test if etelcalcetide makes bone and blood-vessels healthier.
- Conditions
- Chronic Kidney Disease Mineral and Bone Disorder, Renal Osteodystrophy, Vascular Calcification, Hyperparathyroidism; Secondary, Renal
- Trial name
- Parsabiv-MBD (NCT03960437)
- Testing
- Etelcalcetide
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Thomas Nickolas, MD MS
Secondary Hyperparathyroidism, End-stage Kidney Disease
The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKD
Patients with end-stage kidney disease (ESKD) have an increased risk of cardiovascular mortality. High parathyroid hormone (PTH) from secondary hyperparathyroidism leads to increased efflux of phosphate and calcium from bone…
- Trial name
- CaT50HD (NCT06398002)
- Testing
- Dialysate calcium 1.50 mmol/L
- Volunteers
- 48 people
- Sponsor
- Iain Bressendorff
Osteoporosis, Sarcopenia
Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle?
The purpose of this study is to examine whether adding the basic salt potassium bicarbonate to the diet will have a positive effect on how dietary protein affects your bone and muscle.
- Trial name
- NCT00730184
- Testing
- potassium bicarbonate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Tufts University
Scleroderma, Calcinosis Cutis
Effectiveness of ESWT and PNF in Scleroderma With Calcinosis
Investigation of the effects of ESWT and PNF exercises added to ESWT on calcinosis in Ssc patients. Calcinosis cutis is a common, difficult-to-treat manifestation of systemic sclerosis associated with high morbidity.
- Trial name
- NCT05870852
- Testing
- Extracorporeal Shock Wave Therapy (ESWT), PNF
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Osteoporosis, Osteopenia
Encouraging Calcium Absorption and Bone Formation During Early Puberty
Increasing bone mass during puberty can ultimately decrease the risk of developing osteoporosis, which causes bones to weaken and break more easily later in life.
- Trial name
- NCT00022867
- Testing
- Nondigestible oligosaccharide (NDO)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hypocalcemia
Early Prediction of Hypocalcaemia Following Thyroid Surgery
150 patients divided into two groups.The experimental group was submitted at the assay of iPTH six hours after surgery whilst the control group was submitted to a daily assay of serum calcium and phosphorus.
- Trial name
- NCT02853721
- Testing
- iPTH, no dosage of iPTH
- Volunteers
- 150 people
- Sponsor
- University of Cagliari
Sinus Floor Augmentation, Maxillary Sinus
Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study
The purpose of this split-mouth clinical study is to evaluate the clinical, radiographic and histological outcomes of lateral window sinus augmentation with a bovine xenograft or a CPS putty bone substitute in posterior maxillary…
- Trial name
- NCT01942304
- Testing
- Calcium phosphosilicate alloplastic bone putty in direct sinus augmentation, Anorganic bovine bone mineral in direct sinus augmentation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
Vascular Calcification, Hemodialysis
Analysis of the Influence of Dialysis Fluid Composition on Vascular Calcification in Patients With Chronic Kidney Disease Undergoing Hemodialysis
The goal of this clinical trial is to find out if using a citrate-based dialysate with added magnesium during hemodialysis can help slow down or prevent the hardening of blood vessels (vascular calcification) in adults on…
- Conditions
- Vascular Calcification, Hemodialysis, Cardiovascular Disease (CKD)
- Trial name
- CalCio-HD (NCT07163936)
- Testing
- Citrate dialysate with magensium supplementation, Acetate dialysate
- Volunteers
- 80 people
- Sponsor
- Hospital Clinic of Barcelona
Renal Osteodystrophy
Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD
The proposed 6 month pilot and feasibility randomized trial will evaluate LMMS as an anabolic stimulus to bone in 30 adults on maintenance hemodialysis.
- Trial name
- NCT00364234
- Testing
- Low magnitude mechanical stimuli
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Contraception
Study of Treatment With the Combination of Drospirenone Plus Ethinyl Estradiol Plus Levomefolate Calcium in Mexican Women Seeking Contraception
The objective of this study is to compare the red blood cell (RBC) and plasma concentrations of folate in subjects treated with drospirenone (DRSP)/ethinyl estradiol (EE) plus levomefolate calcium (L-5-MTHF) at 24 weeks with…
- Trial name
- NCT01902264
- Testing
- EE20/DRSP/L-5-MTHF (Beyaz, BAY98-7071)
- Where
- Mexico
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bayer
Hypertension, Vitamin D Deficiency
Effect of Vitamin D Replacement During Winter Months in Patients With Hypertension
High blood pressure is related to increased risk of cardiovascular disease and death, and accounts for approximately 8 mill deaths worldwide each year.
- Trial name
- NCT01166165
- Testing
- Cholecalciferol
- Where
- Denmark
- Volunteers
- 136 people
- Sponsor
- Regional Hospital Holstebro
Renal Injury, Regional Citrate Anticoagulation
Effects of Different Continuous Renal Replacement Therapy Patterns on Ionized Calcium in Patients With Citrate Anticoagulants Using Calcium-containing Replacement Solutions
It is unclear whether different modes of continuous renal replacement therapy (CRRT) impact post-filter ionized calcium concentrations during regional citrate anticoagulation (RCA) when using calcium-containing replacement fluid.
- Conditions
- Renal Injury, Regional Citrate Anticoagulation, Continuous Renal Replacement Therapy
- Trial name
- NCT06021080
- Testing
- CVVH, CVVHD
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fujian Provincial Hospital
Alveolar Bone Loss
Clinical Trial on the Safety and Efficacy of Magnesium Doped Calcium Silicate 3d Alveolar Bone Repair Unit for Periodontal Bone Defects
The goal of this clinical trial is to test in height increment of alveolar bone and safety evaluation index. The main question it aims to answer are: The safety and effectiveness of magnesium calcium silicate three-dimensional…
- Trial name
- NCT05743452
- Testing
- GBR with CS@Mg
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Periapical Periodontitis, Root Canal Infection
Antibacterial Efficacy of Bioceramic and Calcium Hydroxide Intracanal Medicaments
This study evaluates the antibacterial effectiveness of two different intracanal medicaments, Bio-C Temp and UltraCal XS , in mandibular molar teeth with chronic apical periodontitis.
- Conditions
- Periapical Periodontitis, Root Canal Infection, Intracanal Medicaments
- Trial name
- NCT07671326
- Testing
- Root canal treatment with Bio-C Temp, a calcium silicate-based bioceramic intracanal medicament, Root canal treatment with UltraCal XS, a calcium hydroxide-based intracanal medicament
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Bone Marrow Transplantation
An Adaptive Phase I Study to Evaluate the Safety, Efficacy and Dose Responses of Ronacaleret in Healthy Human Volunteers
Ronacaleret is an orally administered CaSR antagonist which has previously been demonstrated to transiently increase PTH in both animals and humans.
- Trial name
- NCT01466335
- Testing
- Ronacaleret (100mg tablet)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Osteopenia, Osteoporosis, Sarcopenia
Functional and Metabolic Effects of Fonte Fausta® Water on Bone and Muscle Health in Osteoporotic Patients
This clinical study investigates the effects of Fonte Fausta® water on bone and muscle metabolism, as well as quality of life, in patients with osteoporosis or osteopenia, with or without sarcopenia.
- Trial name
- FOCUS (NCT06851676)
- Testing
- water supplemented by calcium
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ANTIMO