Clinical trials: Calcium
Endocrine System Diseases, Vitamin D Deficiency
Serum Sclerostin Level & Treatment of Vitamin D Deficiency
The aim of this study is to determine serum sclerostin levels and change in serum sclerostin levels in patients with Vitamin D deficiency treated with calcium and vitamin D.
- Trial name
- OMSOST (NCT01553344)
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Bagcilar Training and Research Hospital
Calciphylaxis, Calcific Uremic Arteriolopathy
Double-blind Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopathy
To evaluate the efficacy of Sodium Thiosulfate (STS) compared to placebo, in reducing analgesic requirement in subjects with calcific uremic arteriolopathy (CUA) during an initial 28-day treatment phase.
- Trial name
- NCT02527213
- Testing
- Sodium thiosulfate
- Where
- 3 sites in United States
- Sponsor
- American Regent, Inc.
Phosphate Diabetes, X-linked Hypophosphatemia
Phosphorus-31 Spectroscopy in Phosphate Diabetes
Phosphate diabetes is defined by urinary phosphate wasting due to impaired tubular reabsorption. It can be classified based on either a genetic or acquired origin.
- Trial name
- Phos-ATP (NCT06921720)
- Testing
- intra-muscular ATP values in phosphate diabetes, intra-muscular phosphate values in phosphate diabetes
- Where
- 2 sites in France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Fertilization
Artificial Assisted Activation Following in Fertilization Failure
Fertilization failure is a common problem in assisted reproductive Technology (ART). The main reason for fertilization failure of conventional IVF fertilization is sperm penetration failure, and the main reason of ICSI is…
- Trial name
- NCT04523103
- Testing
- Artificial Assisted Activation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Osteoporosis, Postmenopausal
A Study to Compare the Efficacy of Alendronate With and Without Calcium or Calcium Alone In the Treatment of Osteoporosis in Postmenopausal Women (0217-088)(COMPLETED)
The purpose of this study is to see how well alendronate and calcium as compared to calcium alone increase bone density in postmenopausal women with osteoporosis
- Trial name
- NCT00398606
- Testing
- MK0217, alendronate sodium / Duration of Treatment : 2 Years, Comparator : calcium carbonate /Duration of Treatment : 2 Years
- Volunteers
- 650 people
- Sponsor
- Organon and Co
Breast Cancer, Prostate Cancer
Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid
This is an open-label exploratory study of CTAP101 Capsules in patients with bone metastases arising from either breast or prostate cancer, who are taking anti-resorptive therapy.
- Conditions
- Breast Cancer, Prostate Cancer, Bone Neoplasms, Hypocalcemia
- Trial name
- NCT02274623
- Testing
- CTAP101 Capsules
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- OPKO Health, Inc.
Thalassemia Major
Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
This study aims to investigate the use of amlodipine, a drug that blocks the uptake of calcium into cells, in the prevention and treatment of iron overload in patients with thalassemia major.
- Trial name
- AnloThal (NCT01125254)
- Testing
- Amlodipine
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Campinas, Brazil
Degenerative Disc Disease
Clinical Study of rhBMP-2/BCP With the TSRH® Spinal System for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease
This study is designed to assess the safety and effectiveness of the rhBMP/BCP/TRSH Spinal System in treatment of the patients with degenerative disc disease.
- Trial name
- NCT01494454
- Testing
- rhBMP-2/BCP/TSRH® or rhBMP-2/BCP/CD HORIZON® Spinal System, Autograft/TSRH® or autograft/CD HORIZON® Spinal System.
- Volunteers
- 197 people
- Sponsor
- Medtronic Spinal and Biologics
Postoperative Pain, Acute
Postoperative Pain Evaluation Of Novel Bioceramic-Based Root Canal Sealers
Brief Summary: The purpose of this study was to evaluate the effect of MTA-Bioseal, GuttaFlow bioseal, and NeoSealer Flo calcium-silicate based root canal sealers on postobturation pain in teeth with asymptomatic irreversible…
- Trial name
- NCT06515756
- Testing
- Post operative pain assessment after root canal treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Colorectal Cancer
CONCEPT: Comparison of Oxaliplatin vs Conventional Methods With Calcium/Magnesium in First-Line Metastatic Colorectal Cancer
The primary rationale for this study is to develop an optimized schedule of administration of FOLFOX + bevacizumab that maximizes the efficacy and safety of this regimen when administered to patients with advanced colorectal…
- Trial name
- NCT00129870
- Testing
- oxaliplatin
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Sanofi
Hypophosphatemia, Rickets
The Impact of Phosphate Metabolism on Healthy Aging
Determine the association between duration and dose of chronic conventional therapy with Pi and renal (nephrocalcinosis/nephrolithiasis), vascular (endothelial function), and cardiovascular function (echo- cardiography) in…
- Conditions
- Hypophosphatemia, Rickets, Hypercalciuria, XLH
- Trial name
- NCT03771105
- Testing
- phosphate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Peripheral Arterial Disease, Claudication, Intermittent
Arterial Imaging of Inflammation and Resolution After Endovascular Surgery
This study evaluates the local inflammatory and resolution response of patients undergoing peripheral vascular intervention like an angioplasty of the superficial femoral artery (SFA) or popliteal artery, or stenting of the iliac…
- Conditions
- Peripheral Arterial Disease, Claudication, Intermittent, Claudication, PAD
- Trial name
- AIIRES (NCT03590769)
- Testing
- 18F-FDG
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
in Vitro Fertilization
AOA Versus Non-AOA in Low Prognosis Patients by the POSEIDON Criteria
Poor ovarian response (POR) remains one of the significant challenges of Assisted Reproductive Technology (ART). Facing difficulties related to clinical practice, optimizing the embryo culture process is necessary to improve the…
- Trial name
- NCT05402605
- Testing
- ICSI with AOA, ICSI without AOA
- Where
- Vietnam
- Volunteers
- 528 people
- Sponsor
- Mỹ Đức Hospital
Osteopenia, Renal Osteodystrophy
Osteopenia and Renal Osteodystrophy: Evaluation and Management
The purpose of this study is to demonstrate whether pamidronate will preserve or increase bone mass in patients with adynamic bone disease, caused by low bone turnover.
- Trial name
- NCT00108394
- Testing
- pamidronate
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Aortic Calcification Valve, Aortic Valve Stenosis
Analysis and Comparative Evaluation of Aortic Calcium by Computed Tomography and Histopathology in Patients With Aortic Stenosis
This study evaluates and compares aortic calcium by computed tomography and histopathology in patients with aortic stenosis.
- Trial name
- NCT04344353
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Primary Hyperparathyroidism, Hypercalcemia
Primary Hyperparathyroidism (PHPT): Early Effect of Vitamin D
Primary hyperparathyroidism (PHPT) is a common disease that occurs in 1 in 10,000 people every year. In the presence of this condition, the parathyroid glands produce excessive amounts of parathyroid hormone (PTH), which…
- Conditions
- Primary Hyperparathyroidism, Hypercalcemia, Vitamin D Deficiency, Osteoporosis
- Trial name
- NCT01329666
- Testing
- Vitamin D3
- Where
- United States
- Sponsor
- Columbia University
Coronary Artery Disease
Assessment of Patients With suspeCted Coronary Artery Disease by Coronary calciUm fiRst strATegy vErsus Usual Care Approach.
The cost of medical care in the United States far exceeds that of all other advanced economies and continues to accelerate at a rate unacceptable to our society, due primarily to the high costs of new imaging technologies and…
- Trial name
- ACCURATE (NCT03972774)
- Testing
- PET Stress Test, Non-PET Medical Management
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Intermountain Health Care, Inc.
Pseudohypoparathyroidism and Pseudopseudohypoparathyroidism, Pseudohypoparathyroidism Type Ia
Glucose Homeostasis in Pseudohypoparathyroidism
It is increasingly recognized that Pseudohypoparathyroidism type 1A (PHP1A) is associated with an increased risk of type 2 diabetes but the mechanism is unknown.
- Conditions
- Pseudohypoparathyroidism and Pseudopseudohypoparathyroidism, Pseudohypoparathyroidism Type Ia, Albright Hereditary Osteodystrophy
- Trial name
- NCT03761290
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Vanderbilt University Medical Center
Ergocalciferol
Pilot Study: The Effect of Ergocalciferol on Plasma Mucin-1 Levels
To determine if a one-time oral administration of ergocalciferol results in a decline in plasma mucin-1 levels in healthy individuals and individuals with ADTKD-MUC1.
- Trial name
- NCT03747523
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences