Clinical trials: Calcium Disorder
Chronic Kidney Disease Mineral and Bone Disorder
Phosphorus Absorption in Healthy Adults and in Patients With Moderate Chronic Kidney Disease
Chronic kidney disease (CKD) affects approximately 26 million Americans with many more at risk for disease development. Elevated serum phosphorus (P) and related abnormalities in P homeostasis due to progressive loss of kidney…
- Trial name
- NCT03108222
- Testing
- Phosphorus Absorption Test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Rickets, Osteomalacia
Maternal and Infant Vitamin Status During the First Nine Months of Infant Life
In this study the investigators wanted to assess vitamin D status and possible consequences of low plasma 25-hydroxyvitamin D levels in a population of healthy mothers and their infants, in the community of Aarhus, Denmark.
- Conditions
- Rickets, Osteomalacia, Osteoporosis
- Trial name
- NCT02548520
- Testing
- Blood and breastmilk samples
- Where
- Denmark
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pseudohypoparathyroidism, Albright Hereditary Osteodystrophy
Early-onset Obesity and Cognitive Impairment in Children With Pseudohypoparathyroidism
Pseudohypoparathyroidism type 1a (PHP1a) is a rare disease that causes childhood obesity and learning difficulties. This study will investigate eating behaviors and perform cognitive testing on children with PHP1a.
- Trial name
- NCT02411461
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Kidney Stone, Kidney Calculi
Gut Oxalate Absorption in Calcium Oxalate Stone Disease
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased absorption of dietary oxalate, which would lead to increased urinary excretion of oxalate.
- Conditions
- Kidney Stone, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate
- Trial name
- NCT06331546
- Testing
- Low-oxalate diet, High-oxalate diet, soluble oxalate gut absorption test
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
Bioavailability Study of Amlodipine Besylate/Atorvastatin Calcium Tablets 10/80 mg Under Fed Condition
This study is to assess the bioequivalence between Amlodipine besylate/Atorvastatin calcium Tablets 10mg/80mg of Dr. Reddy's Laboratories Limited, India and CADUET® (amlodipine besylate and atorvastatin calcium) tablets 10mg/80mg…
- Trial name
- NCT02292069
- Testing
- Amlodipine besylate/Atorvastatin calcium
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Hepatitis C, Hypertension
A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers
The purpose of this study is to evaluate the pharmacokinetic interactions between the hepatitis C NS3 protease inhibitor boceprevir and the calcium channel blockers amlodipine and diltiazem in healthy volunteers.
- Trial name
- NCT01549496
- Testing
- Amlodipine, Diltiazem
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Periodontitis, Inflammation
Calcium-vitamin D & Periodontal Therapy for Improving Metabolic and Inflammatory Profile Among Pregnant Women
The improvement of maternal and child health remains a key issue in global health. Production and improved accessibility of healthy and nutrient-rich milk-based products could potentially tackle health and nutrition inequalities…
- Trial name
- IMPROVE (NCT03148483)
- Testing
- Early PT, Delayed PT, Fortified Milk
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Coronary Artery Disease, Endothelial Dysfunction
Predictors of Coronary Artery Calcium Progression in Adults With a Prior Zero Coronary Artery Calcium Score
This study is a non-randomized prospective cohort study that will define the rate of index atherosclerotic plaque development in adults with a prior coronary artery calcium (CAC) score of 0 given prior CAC zero > 5 years…
- Conditions
- Coronary Artery Disease, Endothelial Dysfunction, Atherosclerosis
- Trial name
- NCT02636062
- Volunteers
- healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Osteoporosis, Bone Loss
Dairy Foods Compared to Dietary Supplements and Bone Health
Does the consumption of dairy foods reduce the rate of bone loss in older women more than calcium and vitamin D supplements.
- Conditions
- Osteoporosis, Bone Loss, Osteopenia
- Trial name
- FL-83 (NCT01394484)
- Testing
- Intervention I, Intervention II
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Ovarian Hyperstimulation Syndrome
Calcium for Prevention of Ovarian Hyperstimulation Syndrome
There are many protocols for prevention of ovarian hyperstimulation syndrome, intravenous calcium is a novel protocol. But still there is lack of evidence of it is real effect in prevention of OHSS \& the mechanism of its action…
- Trial name
- OHSS (NCT01427335)
- Testing
- calcium, 0.9 % saline
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Overweight
Calcium Supplementation for a Healthy Weight (CaSHeW)
The objective of this study is to investigate the effect of calcium (Ca) and vitamin D (D) supplemented orange juice (OJ) on weight loss and visceral fat mass in overweight and obese adults.
- Trial name
- CaSHeW (NCT01363115)
- Testing
- Orange Juice fortified with Calcium and Vitamin D, Orange juice without Ca or VitD, Nutritional Counseling
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity
The Effects of Dairy Products on Energy Balance
The aim of the study is to investigate the long time effects of high and low intake of dairy products on fecal fat excretion, weight loss, blood pressure, lipid profile, lipid oxidation and appetite regulation in moderately…
- Trial name
- MEPEB (NCT01199835)
- Testing
- High Calcium intake from dairy products
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Magnesium Effects in Apheresis
This study will determine whether magnesium replacement during apheresis can decrease side effects that donors commonly experience.
- Trial name
- NCT00040235
- Testing
- magnesium
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Osteoporosis
Building Better Bones in Children
Calcium is important for healthy bone growth in children. Poor bone growth and development during childhood can lead to osteoporosis later in life.
- Trial name
- NCT00063037
- Testing
- Behavioral modification - nutrition education
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Furcation Defects, Periodontal Diseases
Mandibular Furcation II Regeneration
Teeth with furcation grade II defects will be treated with open flap debridement and regenerative therapy with biphasic calcium phosphate combined with either enamel matrix proteins or a collagen membrane.
- Trial name
- FURC-II-REGEN (NCT04059445)
- Testing
- Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane), Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain)
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Primary Hypertension
Bioequivalence Study of Sacubitril Alisartan Amlodipine Tablets
This study aims to evaluate the bioequivalence and safety of single oral administration of Sacubitril/Valsartan/Amlodipine Tablets (240mg/5mg) versus Sacubitril/Valsartan Calcium Tablets (240mg) combined with Amlodipine Besylate…
- Trial name
- NCT07486453
- Testing
- Sequence A T-R-T-R, Sequence B R-T-R-T
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.
Pseudohypoparathyroidism, Pseudohypoparathyroidism Type 1a
Theophylline for Treatment of Pseudohypoparathyroidism
Pseudohypoparathyroidism is a genetic disorder with limited treatment options, characterized by early-onset obesity, short stature, hormone resistance and cognitive impairment.
- Conditions
- Pseudohypoparathyroidism, Pseudohypoparathyroidism Type 1a, Albright Hereditary Osteodystrophy
- Trial name
- NCT04240821
- Testing
- Theophylline ER
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jaclyn Tamaroff
Furcation Defects, Periodontal Diseases
Mandibular Furcation III Regeneration (FURC-III-REGEN)
Teeth with furcation grade III defects will be treated with open flap debridement and regenerative therapy with biphasic calcium phosphate combined with either enamel matrix proteins or a collagen membrane.
- Trial name
- FURC-III-REGEN (NCT04059458)
- Testing
- Biphasic calcium phosphate (Straumann Bone Ceramic) + collagen membrane (Straumann Jason Membrane), Biphasic calcium phosphate (Straumann Bone Ceramic) + enamel matrix proteins (Straumann Emdogain)
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Osteoporosis
PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)
Declines in serum calcium during exercise may cause increases in markers of bone resorption. This study will determine if preventing the decline serum ionized calcium experienced at the onset of exercise through the use of a…
- Trial name
- NCT02580604
- Testing
- Calcium Chloride/Calcium Gluconate, Half-Normal Saline
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Caries,Dental
The Effect of Casein Phosphopeptide Amorphous Calcium Phosphate on Affected Dentine
Teeth selected for intervention with Atraumatic Restorative Treatment will receive Glass Ionomer restorations (control) or MI varnish (test) before receiving the Glass Ionomer restoration
- Trial name
- NCT04303767
- Testing
- Casein phosphopeptide amorphous calcium phosphate, Atraumatic restorative treatment
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman