Clinical trials: Calcium Disorder
Osteoporosis
Bone Development in Adolescent Girls: Effects of Calcium and Exercise
Osteoporosis is a major public health problem. Prevention of osteoporosis depends in part on good bone development in childhood and adolescence.
- Trial name
- NCT00063011
- Testing
- Calcium rich diet, Weight bearing exercise
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Necrotic Pulp, Acute Apical Periodontitis of Pulpal Origin
Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide Medicament
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT06653608
- Testing
- Nano-reinforced calcium hydroxide medicament, Calcium hydroxide without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Healthy Volunteers, Discoloration of Teeth
Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents
The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application.
- Conditions
- Healthy Volunteers, Discoloration of Teeth, Bleaching Sensitivity
- Trial name
- NCT06855940
- Testing
- Bleaching Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Betül Tokat
Hypocalcemia
Prophylactic Infusion of Calcium Gluconate Reducing the Rate of Hypocalcaemia After Total Thyroidectomy
Post-total thyroidectomy hypocalcaemia is a common complication with the rate ranging from 13-49% in a meta-analysis. However, the rate in UMMC in 2018 and 2019 were 40% and 23% respectively.
- Trial name
- NCT04491357
- Testing
- Calcium Gluconate, Normal saline
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Hypercholesterolemia
Actual Use Trial of Atorvastatin Calcium 10 mg
The purpose of this actual use study is to simulate the over the counter use of atorvastatin calcium 10 mg.
- Trial name
- NCT01964326
- Testing
- Atorvastatin calcium 10 mg
- Where
- 37 sites in United States
- Volunteers
- 1,311 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pulp Necrosis, Postoperative Pain
Evaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar.
The study will aim to evaluate the postoperative pain and bacterial load after application of two intracanal medications in mandibular first molar teeth with necrotic pulp.
- Trial name
- NCT07790796
- Testing
- Root canal treatment with intracanal medication by calcium hydroxide for one week., Root canal treatment with intracanal medication by cocoa husk for one week, Root canal treatment with intracanal medication by calcium hydroxide with cocoa husk for one week.
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Urolithiasis
Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation
Purpose: The aim of this present study is to investigate the effect of vinegar consumption on 24-hour urinary risk factors associated with calcium oxalate urinary stone formation and blood biochemical parameters.
- Trial name
- NCT02649140
- Testing
- Vinegar group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Osteoporosis
Treatment of Calcium Deficiency in Young Women
This study looks at the effects of calcium supplementation on bone density in women in their third decade of life. We placed women aged 19-27 who take in low amounts of calcium in their diets in one of two groups.
- Trial name
- NCT00000426
- Testing
- Calcium supplement
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Creighton University
Dental Caries
Evaluation of Ion Releasing Hybrid Restorative Material
Esthetic and mechanical evaluation of calcium and phosphate releasing hybrid restorative material and fluoride releasing hybrid restorative material versus the conventional nanofilled resin composite in proximal carious lesions…
- Trial name
- NCT04854655
- Testing
- Conventional resin composite, Activa Presto, Giomer
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Exposure, Dental
Biodentine Vital Pulpotomy in Immature Molars
This study aimed to evaluate the clinical and radiographic success of pulpotomy in cariously exposed vital immature first permanent molars using calcium hydroxide and calcium silicate-based material (Biodentine ™).
- Trial name
- NCT04989036
- Testing
- pulpotomy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Allergic Rhinitis
Effects of AkPharma's Calcium Glycerophosphate Nasal Spray Wash
Over 20 million Americans have allergic nasal symptoms including stuffiness, sneezing and a "runny" nose. AkPharma's Calcium Glycerophosphate used as a nasal spray wash is believed to improve these symptoms without side effects…
- Trial name
- NCT01647633
- Testing
- Calcium Glycerophosphate Nasal Spray Wash
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Drexel University
Hyperparathyroidism, Hypercalcemia
Oral Peptones Load in Normocalcemic and Hypercalcemic Primary Hyperparathyroidism and Healthy Subjects
The purpose of this study is to assess if subjects with hyperparathyroidism with normal serum calcium levels have different responses in the calcium regulating hormonal handling compared to a) patients with primary…
- Trial name
- NCT01042626
- Testing
- Oral peptones load
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Eastern Piedmont
Postpartum Hemorrhage
Investigating the Effect of Extracellular Calcium on Oxytocin-induced Human Myometrial Contractility In-vitro
Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide and is caused most commonly by poor uterine muscle tone after delivery.
- Trial name
- NCT02274454
- Testing
- Oxytocin, Calcium
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Kidney Stones, Urolithiasis
Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis
Recent investigations from this group have identified that genetic variants of genes associated with monogenic forms of nephrolithiasis are expressed in idiopathic calcium oxalate kidney stone patients and could influence stone…
- Conditions
- Kidney Stones, Urolithiasis, Calcium Oxalate Urolithiasis
- Trial name
- NCT01127854
- Where
- United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pulpitis
Vital Pulp Therapy to Treat Irreversible Pulpitis
The purpose of this study is to demonstrate non-inferiority of pulpotomy treatment (with new endodontic bio-materials) as a new treatment with one-visit root canal therapy as reference treatment in pain relief and clinical and…
- Trial name
- VPT (NCT00748280)
- Testing
- One-visit root canal therapy, pulpotomy
- Where
- Iran
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Cardiovascular Risk Factors, Insulin Resistance
Pilot Validation of the STELA Preventive Medicine Platform to Reduce Modifiable Health Risk Factors in Adults (CPM-STELA)
This study evaluates a comprehensive digital health platform called STELA, developed at the Center for Preventive Medicine (CPM) of AGEL Hospital Trinec-Podlesi in Czechia.
- Conditions
- Cardiovascular Risk Factors, Insulin Resistance, Obesity, Dyslipidemias
- Trial name
- CPM-STELA (NCT07551960)
- Testing
- STELA Digital Preventive Medicine Platform, Comprehensive Preventive Health Assessment
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Rheumatoid Arthritis, Crohn's Disease
Tumor Necrosis Factor Decreases Vitamin D Dependant Calcium Absorption
This study is a pilot study to determine whether patients with TNFα excess have decreased calcium absorption in response to calcitriol (1,25-dihydroxyvitamin D, the active form of vitamin D) compared to normal controls.
- Trial name
- NCT00427804
- Testing
- calcitriol
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Atlanta VA Medical Center
Vitamin D Deficiency
Effects of Vitamin D Fortification on Vitamin D Metabolite Profiles and Status in Vitamin D Insufficient Individuals
This is a cross-sectional study designed to compare plasma/serum and urine vitamin D metabolite profiles of vitamin D sufficient and insufficient individuals. There are two phases of this study.
- Trial name
- VITD-2013 (NCT02422784)
- Testing
- Rooibos Iced-Tea (Control), Rooibos Tea - Vitamin D3, Rooibos Tea- Vitamin D3 & Calcium
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
CT - Coronary Thrombosis
The Diagnostic Power Of Coronary CT Angiography In Patients With Chest Pain And Zero Calcium Score
To prove the non-used wide diagnostic range of CCTA in diagnosis of other causes of chest pain in addition to the traditional known role in coronary atherosclerosis.
- Trial name
- NCT06552663
- Testing
- CCTA
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Multiple Sclerosis
Safety Trial of High Dose Oral Vitamin D3 With Calcium in Multiple Sclerosis
Vitamin D likely plays a role in the geography of Multiple Sclerosis (MS), and patients at risk and with MS have relatively low Vitamin D levels compared to their normal counterparts.
- Trial name
- VitD4MS (NCT00644904)
- Testing
- Vitamin D3
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Toronto