Clinical trials: Calcium Disorder
Endodontic Disease, Pulp Disease, Dental
Anti-bacterial Potential of Nano Calcium Hydroxide as an Intracanal Medication
The aim of the study is to evaluate the anti-bacterial potential of Nano Calcium Hydroxide as an intracanal medication in primary endodontic treatment of permanent molars.
- Trial name
- NCT06196515
- Testing
- Calcium hydroxide, nano calcium hydroxide
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
White Spot Lesion, Enamel Hypomineralization
Evaluation of CPP-ACP Prophylactic Effect on Enamel Surface During Orthodontic Treatment
This study is aiming in preventing the formation of WSL associated with orthodontic treatment which occurs to more than 50% of orthodontically treated patients through applying CPP-ACP on the enamel surface once every 2 weeks for…
- Trial name
- NCT03187548
- Testing
- Casein Phosphopeptide-Amorphous Calcium Phosphate Dental Paste
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Insulin Resistance
The Effects of the Food Preservative Propionic Acid in Post-prandial Metabolism
Propionic acid (PA) is used as a preservative in foods such as cheeses, baked goods, or additive for artificial fruit flavors. The U.S.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- Walnut (NCT01889446)
- Testing
- Calcium propionate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Glucose Intolerance, Type 2 Diabetes Mellitus
Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
The purpose of the randomized trial is to quantify the effect of vitamin D and calcium supplementation on beta-cell function, insulin sensitivity, glucose tolerance and systemic inflammation and other cardiometabolic outcomes in…
- Conditions
- Glucose Intolerance, Type 2 Diabetes Mellitus, Metabolic Syndrome
- Trial name
- CaDDM (NCT00436475)
- Testing
- Vitamin D3 2,000 IU orally once daily, Calcium Carbonate 400 mg orally twice daily
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Osteoporosis, Vascular Calcification
Effect of Vitamin K on Age-Related Bone Loss and Vascular Calcification
The purpose of this study is to determine if supplemental vitamin K will reduce age-related bone loss in elderly men and women above that achieved by supplementation.
- Conditions
- Osteoporosis, Vascular Calcification, Inflammation
- Trial name
- NCT00183001
- Testing
- Vitamin K
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Hypertension
Learning Implementation of Guideline-based Decision Support System for Hypertension Treatment: Testing Alternative Antihypertensive Regimens Using ACE-Inhibitors, Calcium Channel Blockers and Diuretics (LIGHT-ACD)
This trial aims to compare the efficacy of several guideline-based hypertensive medication regimens initiated with Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker [A], Calcium Channel Blocker [C] and Diuretic…
- Trial name
- NCT03587103
- Testing
- Protocol initiate with A, Protocol initiate with C, Protocol initiate with D
- Where
- 3 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Periapical Abscess
Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
Investigators observed the clinical and radiographic healing of periapical lesion using Chitosan mixed with calcium hydroxide and compared it with triple antibiotic paste when used as intracanal medicament in 3months, 6 months…
- Trial name
- NCT04319575
- Testing
- root canal treatment and intracanal medicament
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Atherosclerosis, Plaque, Atherosclerotic
Assessment of Coronary Artery Calcium in Active Duty Enlisted Military Members With 10 or More Years of Service
Hypothesis: Enlisted military members with 10 or more years of service and at least one cardiovascular risk factor will demonstrate a higher risk of future cardiac events as assessed by coronary artery calcium (CAC) scoring than…
- Trial name
- NCT02009930
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Infection, Human Immunodeficiency Virus
Relative Bioavailability Study of a Fixed-dose Combination Dolutegravir/Abacavir/Lamivudine Dispersible Tablet
This is an open-label, randomized, crossover study in healthy adult subjects with 5 treatment groups over 5 dosing periods. This study will evaluate pharmacokinetic parameters and relative bioavailability of a dispersible…
- Trial name
- NCT02893488
- Testing
- DTG/ABC/3TC FDC DISPERSIBLE TABLET, EPZICOM (ABC/3TC), TIVICAY (DTG)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Osteoporosis, Aging
Exercise Mode and Acute Bone Resorption
Endurance exercise is often recommended to improve cardiometabolic health and maintain bone health throughout life and to prevent osteoporotic fracture.
- Trial name
- NCT04815824
- Testing
- Exercise Mode
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Osteoporosis
Study on the Predictive Value of the Natural Calcium Isotope Ratio in Urine and Serum for the Diagnosis of Osteoporosis
The study aims at investigating whether the natural calcium isotope ratio (δ44/40Ca) in urine and serum differs between postmenopausal women aged 50 to 75 years suffering from osteoporosis and a healthy control group and whether…
- Trial name
- NCT02967978
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Clinical Research Center Kiel GmbH
Ischemic Heart Disease, Silent Myocardial Ischemia
Early Detection of Silent Myocardial Ischemia
Early-Synergy investigates a diagnostic imaging approach in asymptomatic individuals from the general population for early detection of silent myocardial ischemia and cardiac dysfunction.
- Conditions
- Ischemic Heart Disease, Silent Myocardial Ischemia, Cardiovascular Diseases
- Trial name
- EarlySynergy (NCT04680338)
- Testing
- CMR stress perfusion imaging
- Where
- Netherlands
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Pim van der Harst
Hemodyalysis, Kidney Tansplant
Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients
This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general…
- Conditions
- Hemodyalysis, Kidney Tansplant, Osteoporosis, CKD-MBD - Chronic Kidney Disease Mineral and Bone Disorder
- Trial name
- NCT07141043
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Osteoporosis, Secondary Hyperparathyroidism
Calcium and Vitamin D Malnutrition in Elderly Women
This study is designed to test whether calcium supplementation alone or calcium plus vitamin D reduces the incidence of fractures, reduces high parathyroid secretory activity, and halts bone loss in a population-based sample of…
- Trial name
- NCT00352170
- Testing
- calcium supplementation, calcium and vitamin D3 supplementation
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Creighton University
Hyperlipidemia
A Clinical Trial of HRS-1301 on the Pharmacokinetics of Rosuvastatin Calcium Tablets in Healthy Subjects
The study was designed to evaluate the pharmacokinetic effects of rosuvastatin calcium tablets after oral administration of HRS-1301 in healthy subjects.
- Trial name
- NCT07097831
- Testing
- HRS-1301 Tablets, Rosuvastatin Calcium Tablets
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Necrotic Pulp
Post Operative Pain and Level of Endotoxins With Calcium Hydroxide and Calcium Hydroxide Mixed With Chlorhexidine in Treating Necrotic Teeth
The aim of this prospective in vivo randomized clinical trial to evaluate influence of combination of calcium Hydroxide (CALCIPAST Paste, Poland) and chlorhexidine Gel 2% (Gluco-Chex 2%, Cerkamed, Poland) in comparison to calcium…
- Trial name
- NCT03009006
- Testing
- Chlorhexidine 2% gel - Calcium Hydroxide Paste - Non-Setting, Calcium Hydroxide Paste - Non-Setting
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy, Long QT Syndrome
Ventricular Repolarization During the Pregnancy-to-Postpartum Transition (QuTe)
Pregnancy and the postpartum period are accompanied by marked changes in heart rate, circulating hormones, and electrolyte balance that may influence ventricular repolarization.
- Trial name
- QuTe (NCT02931695)
- Testing
- Evaluation of QT interval duration, Circulating sex hormones levels sample
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Rickets, Osteomalacia
Maternal and Infant Vitamin Status During the First Nine Months of Infant Life
In this study the investigators wanted to assess vitamin D status and possible consequences of low plasma 25-hydroxyvitamin D levels in a population of healthy mothers and their infants, in the community of Aarhus, Denmark.
- Conditions
- Rickets, Osteomalacia, Osteoporosis
- Trial name
- NCT02548520
- Testing
- Blood and breastmilk samples
- Where
- Denmark
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.