Clinical trials: Calcium Phosphate Kidney Stones
Calcium Phosphate Kidney Stones
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.
- Trial name
- NCT06003348
- Testing
- OHCit- standard dose, Potassium Citrate, OHCit- low dose
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stone
Potassium Citrate Supplementation vs. Dietary Counseling
The purpose of this study is to compare the role of potassium citrate supplementation with dietary education versus dietary education alone in the reduction of stone risks and events in patients with predominantly calcium…
- Trial name
- NCT01980004
- Testing
- Potassium Citrate Supplementation, Dietary Education
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Nephrolithiasis
Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers
Kidney stones continue to affect more and more people in the United States with the most recent estimate being 1 in 9 people will develop a stone in their life.
- Trial name
- NCT06974357
- Testing
- Genetic testing
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ryan L Steinberg
Kidney Stones, Urolithiasis, Hypocitraturia, Nephrolithiasis
Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones
Kidney stones affect 1 in every 11 people in the US each year. In patients with kidney stones who are prescribed medications for stone management, only 30.2% are adherent to a medication regime and even fewer, only 13.4 % are…
- Trial name
- NCT07408076
- Testing
- Potassium Citrate, Sodium Bicarbonate
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Calcium Phosphate Kidney Stones
Treatment for Calcium Phosphate Kidney Stone Disease
The investigators will examine in two studies whether citric acid or potassium citrate can reduce calcium phosphate saturation in urine of Calcium Phosphate stone formers.
- Trial name
- NCT01754779
- Testing
- Citric Acid, Potassium Citrate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Calculi, Calcium Oxalate Kidney Stones
Bryophyllum Pinnatum Tea as a Novel Treatment for Recurrent Kidney Stone Formers
The aim of this randomized placebo-controlled double-blind crossover clinical trial is to test the ability of a traditional tea made from the leaf of the Bryophyllum pinnatum (B.
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Calcium Phosphate Kidney Stones
- Trial name
- NCT06987084
- Testing
- Bryophyllum pinnatum tea
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Indra Gupta
Kidney Calculi, Calcium Oxalate Kidney Stones
Evaluating the Vitamin K2 Status of Calcium-based Stone Formers
This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study…
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Vitamin K 2, Human
- Trial name
- NCT05081960
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Calcium Phosphate Kidney Stones
Methionine for CaPhos Stone
Some kidney stones including calcium phosphate and struvite stones form in vary alkaline urine (high pH). Currently available medication for stone prevention, namely citrate supplementation, can lead to even higher pH levels and…
- Trial name
- NCT07465367
- Testing
- L-Methionine
- Volunteers
- 15 people
- Sponsor
- Ryan L Steinberg
Nephrolithiasis, Calcium Oxalate, Nephrolithiasis, Calcium Phosphate
Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study
In this study the investigators propose to use a daily dose of 45 mg (30 mg at 8 AM and 15 mg at 4 PM). This relatively small well-tolerated dose is likely to persistently increase urine volume and reduce urine supersaturation…
- Trial name
- NCT02096965
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Lithiasis, Nephrolithiasis
Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock Wave Lithotripsy.
The extracorporeal shock wave lithotripsy (ESWL) is the treatment of choice for most stones in any of their locations. It is about breaking the stone without surgically intervening on the patient and getting him to expel the…
- Trial name
- FAGOTRICIA (NCT05525130)
- Testing
- Food supplement
- Where
- 3 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Arafarma Group, S.A.