Clinical trials: Calculi
Calculus, Dental, Periodontal Diseases
Development of a New Toothpaste for the Removal of Dental Calculus.
Periodontal disease is amongst the most prevalent oral diseases worldwide and in North America. According to the 2007/09 Canadian Health Measures Survey, 16% of Canadian adults and 24% of older adults, 60 to 79 years of age, were…
- Conditions
- Calculus, Dental, Periodontal Diseases, Periodontal Inflammation
- Trial name
- NCT04381403
- Testing
- Bio-descaling D-Tart toothpaste, Crest® toothpaste
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Faleh Tamimi
Urolithiasis, Nephrolithiasis
Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy
In latest literature more evidence is available about the positive effect of alpha blocker on stone expulsion from the ureter. Patients benefit from less pain and shortening time to stone expulsion.
- Conditions
- Urolithiasis, Nephrolithiasis, Ureterolithiasis
- Trial name
- NCT00409227
- Testing
- Alpha blocker-alfuzosin
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Calculus of Upper Urinary Tract (Disorder)
The Impact of Renalof® Dietary Supplement on Upper Urinary Tract Stone Volume
Following informed consent, all recruited patients will have a baseline non-contrast CT scan performed at the radiology department of "G.
- Trial name
- AMMOS (NCT04860492)
- Testing
- Renalof 325mg
- Where
- Greece
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Cholelithiasis
Lithotripsy for the Treatment of Gallstones
The purpose of this study is to determine the effectiveness and safety of using the Medstone lithotripter to treat single non-calcified gallstones from 4 to 20 mm in diameter.
- Trial name
- NCT00042549
- Testing
- Extracorporeal Shock Wave Lithotripsy, ursodiol
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Medstone International
Calcular Obstructive Jaundice
Primary Precutting Versus Conventional Over-the-Wire Sphinchterotomy For Managment Of Large Common Bile Duct Stones
During the last decades, endoscopic retrograde cholangiopancreatography (ERCP) has become the standard of care for the treatment of many pancreaticobiliary diseases [Canena et al., 2014].
- Trial name
- NCT06106724
- Testing
- sphincterotomy, precutting of the papilla by knife needle
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Kidney Stones
Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy
Tamsulosin is an alpha blocker usually prescribed for urinary complaints that has been shown to have some benefit in allowing kidney stones to pass through the ureter.
- Trial name
- NCT01560091
- Testing
- silodosin, Extra-corporeal shock wave lithotripsy, Tamsulosin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Kidney Stones, Kidney Calculi
Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease
The goal of this clinical trial study is to test if patients with idiopathic calcium oxalate kidney stones have an increased production of oxalate by the body, which would lead to increased urinary excretion of oxalate.
- Conditions
- Kidney Stones, Kidney Calculi, Urolithiasis, Urolithiasis, Calcium Oxalate
- Trial name
- NCT06989320
- Testing
- Low-oxalate diet and glycolate dosing, Oral glycolate dosing, Oral 13C- ascorbic acid dosing
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Renal Stones
RIRS Versus ESWL for the Treatment of Renal Stones
To evaluate the effectiveness of RIRS (retrograde intrarenal surgery) and ESWL (extracorporeal shockwaves lithotripsy) in the treatment of renal stone ranging form 6 to 20 mm size.
- Trial name
- NCT02645058
- Testing
- RIRS, ESWL, Rigid and flexible ureteroscope
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Kidney Stone, Calculi, Renal
Our Stone Fixation Technique to Improve Efficiency and Results of Peumatic Lithotripsy in Suction Mini-PCNL.
Prospective study to assist safty and efficieny of our technique of using peumatic lithotripsy with suction mini-pcnl.
- Trial name
- NCT07328659
- Testing
- Peumatic lithotripsy in mini-pcnl
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Yasser Gamil Elnagar
Intimate Partner Violence (IPV), Earning Outcomes
Zithandani Stepping Stones and Creating Futures - Phase 2 Pilot
The goal of this uncontrolled intervention study is to assess whether Zithandani Stepping Stones and Creating Futures is feasible to deliver, acceptable for participants, safe for participants and to estimate effect sizes, in…
- Conditions
- Intimate Partner Violence (IPV), Earning Outcomes, Mental Health, Couple Communication
- Trial name
- NCT06975137
- Testing
- Zithandani Stepping Stones and Creating Futures
- Where
- South Africa
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Renal Stones
Treatment of Renal Stones With Frankincense (Luban)
Frankincense, or olibanum, is the oleogum resin that is harvested from several different trees, an aromatic resin obtained from trees of the genus Boswellia.
- Trial name
- Luban (NCT03924596)
- Testing
- AKBA-Incense (3-acetyl-11-keto-ß-boswellic acid), Potassium Sodium Hydrogen Citrate
- Where
- Oman
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Calculus, Dental
Efficacy of Toothpaste Containing 0.454% Stannous Fluoride as Compared to a Regular Fluoride Toothpaste Containing 0.76% Sodium Monofluorophosphate in Controlling Supragingival Calculus Formation Over a 12-week Period.
To evaluate the comparative clinical efficacy of a test toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate in controlling supragingival calculus…
- Trial name
- NCT07223060
- Testing
- 0.454% stannous fluoride, 0.76% sodium monofluorophosphate
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Stone Ureter
Extra-Corporeal Shock Wave Lithotripsy for Renal and Upper Ureteral Stones in Adults Under Locally Infiltrate d Anaesthetics ; a Clinical Randomized Controlled Study
There are many treatment modalities available for managing renal and upper ureteric stones. They range from completely non-invasive outpatient procedures to invasive procedures requiring hospital admission and increased risks of…
- Trial name
- NCT06462573
- Testing
- locally infilterating anaethesia like lidocaine, general anaethesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urinary Stones, Ureteral Calculus
The Usefulness of Flexible Cystoscopy for Preventing Double-J Stent Malposition After Laparoscopic Ureterolithotomy
The aim of this study was to evaluate the role of flexible cystoscopy in preventing malpositioning of the ureteral stent after laparoscopic ureterolithotomy in male patients.
- Trial name
- FC-DM (NCT03150446)
- Testing
- flexible cystoscopy
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sung Gu Kang
HIV Infections
Stepping Stones Program for Preventing HIV Infection in Residents of Rural South African Communities
This study will evaluate the effectiveness of Stepping Stones, an HIV-prevention education program, versus a brief HIV-focused intervention, in improving sexual health and preventing HIV infection in young residents of rural…
- Trial name
- NCT00332878
- Testing
- Stepping Stones, stepping Stones short
- Where
- South Africa
- Volunteers
- 2,801 people, healthy volunteers welcome
- Sponsor
- Medical Research Council, South Africa
Kidney Stone
The RELIEF™ Ureteral Stent Randomized Controlled Trial
Assessment of the backwards flow of urine from the bladder into the ureter (retrograde urine reflux) after placement of the RELIEF® Ureteral Stent using imaging of the bladder after filling it with contrast and assigning a…
- Trial name
- NCT06720740
- Testing
- RELIEF Ureteral Stent, Standard of Care Ureteral Stent
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego