Clinical trials: Calculus
Gall Stone
RISK FACTORS OF GALL BLADDER STONE
Gallbladder disease is a significant health burden in the developed world and its prevalence has risen by more than 20% in the past three decades In the United States, 20-25 million individuals are affected by gallbladder…
- Trial name
- NCT04822519
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Sohag University
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Kidney Stone
Oxalate Formation From Ascorbic Acid
The purpose of this basic research study is to determine the contribution of endogenous ascorbic acid (AA) turnover to urinary oxalate excretion in both normal BMI and obese adult non-stone formers and calcium oxalate stone…
- Trial name
- NCT04603898
- Testing
- Low Oxalate Diet, Carbon-13 Ascorbic Acid Oral Load
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Diseases, Dental Plaque
Oral Health Literacy Tailored Communication
The purpose of this study to investigate attitude, oral health literacy and psychological factors in order to evaluate if these factors are important for oral health in adults.
- Conditions
- Periodontal Diseases, Dental Plaque, Dental Calculus, Sialorrhea
- Trial name
- NCT01118143
- Testing
- Tailored oral health literacy instruction
- Where
- 2 sites in Norway
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Urinary Calculi, Hyperoxaluria
Proteomic Study of Urinary Stone Disease
Urinary protein levels are not routinely measured in stone patients while there is strong evidence that proteins play a role in the etiology of stones.
- Conditions
- Urinary Calculi, Hyperoxaluria, Calculi
- Trial name
- NCT00199459
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Urolithiasis
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study
Many things, like not drinking enough fluids, contribute to making kidney stones and there is also a genetic tendency. We looked into this in 1998-2000 in 14 families with several stone-formers.
- Trial name
- NCT06211842
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
IPV, Sexual Violence
Stepping Stones and Creating Futures Intervention Trial
This study evaluates whether the behavioural/structural interventions of Stepping Stones and Creating Futures can reduce the incidence of intimate partner violence in urban informal settlements amongst young people.
- Trial name
- NCT03022370
- Testing
- Stepping Stones and Creating Futures
- Where
- South Africa
- Volunteers
- 1,351 people, healthy volunteers welcome
- Sponsor
- University of KwaZulu
Ureteral Calculi
Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone
The purpose of this study is to compare ureteroscopy with and without use of safety guide-wire in treatment of ureteral stone
- Trial name
- NCT03726502
- Testing
- ureteroscopy with safety guide-wire, ureteroscopy alone, without safety guide-wire
- Where
- Iran
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Oral Hygiene
Evaluation of the Influence of Radiofrequency-based Toothbrush on the Accumulation of Calculus
to evaluate the influence of radiofrequency based toothbrush (Silk'n toothwave)on the accumulation of the calculus
- Trial name
- NCT04640857
- Testing
- Silk'n Toothwave
- Where
- Israel
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Calcium Oxalate Urolithiasis
Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion
The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of healthy participants and to determine whether this…
- Trial name
- NCT03752684
- Testing
- Moderately high oxalate/low calcium diet non-colonized, Oxalobacter formigenes, Moderately high oxalate/low calcium diet colonized
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Stones
Extracorporeal Shock Wave Lithotriptor Indicated for Fragmenting Urinary Stones in the Kidney
A total of 20 subjects presenting with urinary stone(s) in the kidney or ureter will be treated with an extracorporeal shockwave lithotripsy device to fragment the stones. Subjects will be followed for 14 days.
- Trial name
- NCT00959153
- Testing
- LithoSpace Extracorporeal Shockwave Lithotripter
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Advance Shockwave Technology GmbH
Determine the Efficacy and Safety of SWL in Renal Stones Larger Than 2 cm in Pediatric Age Group
Extracorporeal Shock Wave Lithotripsy for Treatment of Large Pediatric Renal Pelvic Stone Burden More Than 2 cm
Extracorporeal shock wave lithotripsy (SWL) was first described for pediatric nephrolithiasis in 1986; SWL has been a mainstay of treatment for both renal and ureteral calculi in children .
- Trial name
- NCT05293613
- Testing
- extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Kidney Stones
Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.
We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a…
- Trial name
- DONATE (NCT05519150)
- Testing
- low dose radiation abdomen/pelvis CT scan (stone protocol), Blood draw, 24 hour urine collection
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Indiana University
Kidney Stones
Oxalate-Driven Host Responses in Kidney Stone Disease
This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS).
- Trial name
- NCT05417568
- Testing
- Low Oxalate Diet, High Oxalate Diet
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Stones
Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy
Tamsulosin is an alpha blocker usually prescribed for urinary complaints that has been shown to have some benefit in allowing kidney stones to pass through the ureter.
- Trial name
- NCT01560091
- Testing
- silodosin, Extra-corporeal shock wave lithotripsy, Tamsulosin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Aphthous Stomatitis, Recurrent, Aphthous Stomatitis
Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous Stomatitis
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition.
- Conditions
- Aphthous Stomatitis, Recurrent, Aphthous Stomatitis, Aphthous Ulcer
- Trial name
- NCT06960278
- Testing
- Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5., Control, ALUMSTONE
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Anbar
Endoscopic Retrograde Cholangiopancreatography , Gallstone
Nonradiation-to-endoscopist Endoscopic Retrograde Cholangiopancreatography in Patients With Complexity Level I/II
Radiation exposure may put endoscopists at risk when performing endoscopic retrograde cholangiopancreatography. Although non-radiation endoscopic retrograde cholangiopancreatography was reported in pregnant women in previous…
- Trial name
- NCT02697149
- Testing
- nonradiation-to-endoscopist endoscopic retrograde cholangiopancreatography, standard endoscopic retrograde cholangiopancreatography
- Where
- 2 sites in China
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Gallbladder Cancer, Nutritional and Metabolic Diseases
Chile Biliary Longitudinal Study
Background: The gallbladder is a small organ below the liver. Gallbladder cancer is a leading cause of cancer death among women in Chile. Chile also has among the highest rates of gallbladder cancer and death in the world.
- Trial name
- NCT02692911
- Where
- 3 sites in Chile
- Volunteers
- 4,749 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Urolithiasis
Management of Ureteral Calculi Using Ultrasound Guidance: A Radiation Free Approach
Kidney stones are very common, and can inflict a significant degree of pain and renal damage. Some stones become obstructed in the ureter, the tube that drains the kidney.
- Trial name
- NCT01792765
- Testing
- Ultrasound guidance
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Kidney Stone, Ureteral Stone
The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones
The purpose of this study is to collect real-world evidence on the performance of the SOLTIVE™ Premium SuperPulsed Laser System for laser lithotripsy in ureteroscopy, percutaneous nephrolithotomy (PCNL) and mini PCNL for kidney…
- Trial name
- NCT04556201
- Testing
- SOLTIVE™ Premium SuperPulsed Laser Fiber System
- Where
- 7 sites in United States, Denmark and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Olympus Corporation of the Americas