Clinical trials: Canalicular Stenosis
Epiphora, Nasolacrimal Duct Obstruction
Lacrimal Drainage Resistance Study
Epiphora, or uncontrolled tearing of the eyes, represents a common presenting complaint of patients seen by ophthalmologists. Epiphora may be due to non-obstructive causes, such as tear hypersecretion or functional tear pump…
- Conditions
- Epiphora, Nasolacrimal Duct Obstruction, Canalicular Stenosis, Functional Tear Pump Failure
- Trial name
- LDRS (NCT01766232)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Cleveland Clinic
Lacrimal Stenosis of Both Eyes
Lacrimal Deroofing for Epiphora
Puncto-canalicular abnormalities, such as obstruction and canaliculitis, are a significant cause of epiphora. They involve proximal lacrimal drainage system.
- Trial name
- NCT06983717
- Testing
- lacrimal deroofing
- Where
- United Arab Emirates
- Volunteers
- 39 people
- Sponsor
- Benha University
Epiphora
Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel
Objective: To evaluate the safety and efficacy of topical cyclosporine eye drops (Restasis®) for the treatment of epiphora caused by canalicular stenosis secondary to Docetaxel (Taxotere®) treatment for various cancers.
- Trial name
- NCT00824811
- Testing
- Cyclosporine Eye Drops (Restasis), Lubricant Eye Drops (Refresh Endura™), Fluorometholone Eye Drops (FML Forte®)
- Sponsor
- M.D. Anderson Cancer Center