Clinical trials: Cancer, Colorectal
Advanced Cancers
End of Life Treatment Preferences of Latino Medicare Beneficiaries With Cancer
Objectives: The primary objective of the research project is to investigate how declining health status influences the end-of-life (EOL) treatment preferences in Latino Medicare beneficiaries with cancer and to examine if and how…
- Trial name
- NCT01389830
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
Increasing Colorectal Cancer Screening Uptake With a Patient Navigator
Patients who receive tailored navigation (consisting of a letter and patient navigation services) and get screened will be significantly greater than the control group who receives treatment as usual.
- Trial name
- NCT01506687
- Testing
- Health counselling by nurse navigator, Usual primary care counselling
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Cancer Care Ontario
Colorectal Neoplasms
Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)
The PUMP-IT study is designed to prove the feasibility of HAIP chemotherapy with concomitant standard systemic chemotherapy (FOLFOX and FOLFIRI) in the Netherlands.
- Trial name
- PUMP-IT (NCT04552093)
- Testing
- Floxuridine, Tricumed IP2000V infusion pump
- Where
- Netherlands
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Colonic Neoplasms, Crohn Disease
Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy
The primary objective of this study is to retrospectively compare the perioperative and short-term (discharge through 30 days) outcomes of intracorporeal and extracorporeal anastomosis in minimally invasive right colectomies for…
- Trial name
- NCT03019016
- Testing
- Right Colectomy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Intuitive Surgical
Colorectal Neoplasia, Colorectal Inflammation
Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome
The purpose of this study is to determine whether an association between endomicroscopic pattern and colorectal mucosal microbiome exists.
- Conditions
- Colorectal Neoplasia, Colorectal Inflammation, Hyperplasia, Mucosal Microbiome
- Trial name
- NCT02063919
- Testing
- the mucosal microbiome in the biopsy specimen was analysed
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colorectal Cancer, Pancreatic Adenocarcinoma
Circulating Tumor DNA Exposure in Peripheral Blood
This is a prospective, multi-center, blinded feasibility study. The objective of this study is to test the feasibility of the detection of tumor DNA of a variety of tumors in peripheral blood using a novel process for the…
- Conditions
- Colorectal Cancer, Pancreatic Adenocarcinoma, Gastric Cancer, Hepatocellular Carcinoma
- Trial name
- NCT03517332
- Where
- 6 sites in United States, Switzerland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Quantgene Inc.
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Lung Neoplasms, Pancreatic Neoplasms
Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis Techniques
This is a combined prospective and retrospective observational study aiming to validate a highly sensitive and specific blood-based method for the early diagnosis and post-treatment monitoring of multiple cancers.
- Conditions
- Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms
- Trial name
- NCT07035587
- Testing
- Serial Blood Sampling for Molecular Profiling, One-Time Blood Sampling for Molecular Profiling
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Colorectal Neoplasms
Internet-Based Motivational Interviewing for Colonoscopy
Compared to other racial groups, African Americans have the highest colorectal cancer (CRC) morbidity and mortality rates. Although colonoscopies can prevent CRC, nearly one third of African Americans have not received a…
- Trial name
- NCT03595904
- Testing
- E-Motivate group, Usual Care Group
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Neoplasms, Digestive System Diseases
Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing
The objective of this study is to confirm the sensitivity and specificity of a stool DNA test for detection of colorectal cancer and pre-cancer.
- Conditions
- Colorectal Neoplasms, Digestive System Diseases, Colonic Diseases, Colorectal Cancer
- Trial name
- NCT01600209
- Where
- 13 sites in United States
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Lynch Syndrome
Trial to Compare eConsent With Standard Consent Among Prospective Biobank Participants
The goal of this trial is to determine whether the Sage eConsent framework (presented using an electronic application) is non-inferior to traditional, paper-based, human-mediated consent-and therefore could be part of an…
- Trial name
- NCT04131062
- Testing
- Electronic Consent (iPad)
- Where
- United States
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Colon Cancer, Rectal Cancer
Community Dissemination of an Evidence-based Colorectal Cancer (CRC) Screening Intervention
Filipino Americans have lower rates of colorectal cancer (CRC) screening, later stage of diagnosis and poorer survival relative to other racial/ethnic groups.
- Trial name
- NCT01351220
- Testing
- Educational program and FOBT kits, Educational program and FOBT kits, and technical assistance
- Where
- United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Colorectal Cancer (Diagnosis)
Secondary Care Colorectal Cancer Pathway Review
Bowel cancer (colorectal cancer) is the 4th most common cancer in Scotland. Approximately 4,000 cases are diagnosed annually. Cancer-related deaths in Scotland are higher than other UK nations.
- Trial name
- NCT07430527
- Testing
- Faecal Immunohistochemical test
- Where
- 2 sites in United Kingdom
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Colorectal Cancer
Pilot Evaluation of Fecal Immunologic Test (FIT) in Ontario
Prior to implementation of new colorectal cancer (CRC) screening technology (fecal immunochemical test - FIT) in Ontario, there is a need for a laboratory and field assessment to validate and optimize its use in the Ontario…
- Trial name
- NCT01754896
- Testing
- mailing of FIT kit directly to patient, mailed invitation to pick up lab requisition and then kit, mailing completed kits in for processing
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Colon Cancer
Reducing VA No-Shows: Evaluation of Predictive Overbooking Applied to Colonoscopy
In this research study, investigators use colonoscopy as a case example to evaluate a predictive overbooking model derived using patient-level predictors of absenteeism.
- Trial name
- No-show (NCT01639443)
- Testing
- Predictive no-show overbooking
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Polyps
Metatranscriptomic Markers of Colonic Neoplasia
This study is a collaboration between Viome Life Sciences and Scripps Research Institute to develop and validate a noninvasive molecular diagnostic test for the detection of colorectal polyps.
- Trial name
- NCT07786818
- Testing
- This is an observational study that has no interventions
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Viome
Colonic Neoplasms
Artificial Intelligence for Leaving in Situ Colorectal Polyps.
This two parallel-arms, randomized, multicenter trial is aimed at investigating safety and effectiveness of a Computer-Aided-Diagnosis (CADx)-assisted leave-in-situ strategy (Leave-In-Situ Arm) as opposed to a resect-all strategy…
- Trial name
- NCT05500248
- Testing
- Leave In Situ, Standard
- Where
- Italy
- Volunteers
- 919 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Recurrent or Metastatic Colorectal Cancer
Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer
This is an open-label clinical trial aimed at evaluating the safety and efficacy of the combination treatment of nelmastobart with capecitabine in patients diagnosed with metastatic or recurrent colorectal cancer.
- Trial name
- NCT05990543
- Testing
- Nelmastobart and Capecitabine
- Where
- South Korea
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Colorectal Carcinoma
Implementation Research to Increase Colorectal Cancer Screening Rates Among Low Income and Ethnic Minority Groups
This clinical trial implements research strategies to increase colorectal cancer (CRC) screening rates among low income and ethnic minority groups.
- Trial name
- NCT06090643
- Testing
- Best Practice, Consultation, Educational Intervention
- Where
- United States
- Volunteers
- 9,745 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center