Clinical trials: Cancer
Hepatitis, Hepatocellular Carcinomas
Identification of Specific Modulation Frequencies in Hepatitis B Carriers With and Without Hepatocellular Carcinoma
The propose of this study is to identification of a group of specific amplitude-modulated frequencies of low intensity electromagnetic fields that is associated with biofeedback upon exposure to in patients with hepatitis B…
- Trial name
- THBC-HSL2 (NCT01641276)
- Testing
- Low intensity amplitude-moduled electromagnetic fields
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Colonic Neoplasms, Colonic Adenoma
Hot EMR vs Underwater Cold EMR for Large Colonic Adenomas
This randomized, multi-center trial aims to evaluate the advantages of underwater cold endoscopic mucosal resection technique (CS-EMR) in comparison to the conventional endoscopic mucosal resection technique (EMR) for laterally…
- Conditions
- Colonic Neoplasms, Colonic Adenoma, Colonic Lesion
- Trial name
- COWL (NCT06217250)
- Testing
- Traditional EMR, the cold snare ("CO"), underwater technique ("W"), and the use of submucosal lift ("L") in both study arms
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Sleep, Sleep Disturbances in Children
Cross-sectional Study of Sleep Disturbance in Hong Kong Children With Cancer Comparing With Healthy Counterparts and Children With Other Chronic Diseases
Sleep disturbances are prevalent among children with chronic illnesses, yet the specific impact of cancer on sleep remains underexplored.
- Conditions
- Sleep, Sleep Disturbances in Children, Sleep Disturbances
- Trial name
- NCT07122921
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Adalimumab
A Study Comparing the Pharmacokinetics (PK) of ABP 501 40 mg/0.4 mL (ABP 501-HCF) and ABP 501 40 mg/0.8 ml (ABP 501-LCF) in Healthy Adult Participants
To determine the pharmacokinetic (PK) comparability of ABP 501 40 mg/0.4 mL (ABP 501-HCF) compared to ABP 501 40 mg/0.8 mL (ABP 501-LCF) following single-dose subcutaneous (SC) injection, as assessed principally by area under the…
- Trial name
- NCT05909852
- Testing
- ABP 501-HCF, ABP 501-LCF
- Where
- 3 sites in United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Amgen
Neoplasms, Cancer
PRediction Of Five Usual Tumors Using Blood Test for Risk Assessment and Early Detection
Liquid biopsy technology based on cell-free nucleic acids and protein characteristics has unique advantages and significant application prospects in cancer early detection.
- Trial name
- PROFUTURE (NCT05874648)
- Testing
- Multi-cancer early detection test
- Where
- China
- Volunteers
- 3,830 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Colorectal Neoplasia, Colorectal Cancer
The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong
The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.
- Trial name
- ACNC (NCT04815525)
- Where
- Hong Kong
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mental Health, Bone Marrow Cancer
The Effect of Art-Based Mandala on Mental Health in Bone Marrow Transplant Patients
According to the World Health Organization (WHO), health is not only a state of complete well-being in terms of illness and disability, but also physical mental and social well-being.
- Conditions
- Mental Health, Bone Marrow Cancer, ART
- Trial name
- NCT05488717
- Testing
- art-based mandala application
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Aysenur Uceriz
Chronic Lymphocytic Leukemia
A Phase 1 Study of Novel GS-9973 Tablet Formulations to Evaluate the Effect of Acid Reducing Agents, Relative Bioavailability, and Food Effect on GS-9973 Pharmacokinetics
This is a Phase 1, Open-Label, Adaptive Study of Novel GS-9973 Tablet Formulations to Evaluate the Effect of Acid Reducing Agents, Relative Bioavailability, and Food Effect on GS-9973 Pharmacokinetics.
- Trial name
- NCT01841489
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Chronic Pain Syndrome, Sensitization, Central
Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
A randomized controlled clinical trial will be conducted, involving a psychoeducational activity as the intervention. There will be a control group of patients with non-cancer chronic pain who will continue their usual treatment.
- Conditions
- Chronic Pain Syndrome, Sensitization, Central, Quality of Life, Patient Empowerment
- Trial name
- NCT06440668
- Testing
- Chronic Pain Management Workshop with Non-Pharmacological Therapies
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Metabolic Syndrome, Gastric Cancer
A Metabolomics-based Study to Explore the Mechanism of Remission of Metabolic Syndrome After Radical Gastrectomy
1. Analysis of preoperative and postoperative metabolite changes: Through metabolomics technology, the changes of preoperative and postoperative metabolites in patients with gastric cancer complicated with metabolic syndrome were…
- Trial name
- Metabolomics (NCT06707714)
- Testing
- hypertension, diabetes, fatty liver
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dong Peng
Colorectal Cancer (CRC), Advanced Adenomas (AA)
Collection of Samples USOPTIVAL Study
A prospective multi-center observational study. The study will enroll eligible subjects from the United States to optimize the biomarker panel and evaluate the performance of a cfDNA marker panel selected by the Sponsor for CRC…
- Trial name
- NCT04792684
- Testing
- Optimization of Plasma Circulating Free-DNA (cfDNA) Marker Panel
- Where
- 16 sites in United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Universal Diagnostics
Carpal Tunnel Syndrome
Median Nerve Stenosis in Carpal Tunnel Syndrome
The goal of this observational study is to test the new kind of ultrasound-based measurements in patients with carpal tunnel syndrome.
- Trial name
- NCT05861349
- Testing
- Nerve conduction study, Ultrasound
- Where
- Poland
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Jakub Antczak
Amyloidosis, AL Amyloidosis
BE.Amycon Biobank & Data Registry UZ Leuven
The goal of this study is to collect and store human body material (HBM) of patients with amyloidosis in a biobank "BE.Amycon biobank" for future research and to collect clinical data of patients with amyloidosis in a database…
- Conditions
- Amyloidosis, AL Amyloidosis, Amyloidosis Cardiac
- Trial name
- NCT07172243
- Where
- 2 sites in Belgium
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
NSCLC
Circulating Fibrocytes in Non-small Cell Lung Cancer.
The investigators will collect fibrocytes (CD45+Col-1+) in patients with non-small cell lung cancer (NSCLC). The investigators hypothesize that patients with NSCLC experience expansion of immunosuppressive fibrocytes, which are…
- Trial name
- NCT01998425
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Colorectal Cancer
Colorectal Cancer Screening in Xinxiang City
The primary objective of this study is to evaluate the sensitivity of the fecal protein dual-index test reagent for the detection of colorectal cancer (CRC).
- Trial name
- NCT06785714
- Where
- China
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Breast Cancer, Prostate Cancer
Survivorship Care Plans in a Community Oncology Practice
This is a two part observational study evaluating the feasibility of implementing an EHR-based model within a community oncology practice.
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer
- Trial name
- NCT03028584
- Testing
- Survey
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alcohol Drinking, Sex Behavior
Alcohol and Implicit Process in Sexual Risk Behavior in MSM
The current study is the first empirical investigation that directly addresses the correspondence between responses regarding indicators of risky sexual behavior while under the influence of alcohol in the laboratory and the…
- Conditions
- Alcohol Drinking, Sex Behavior, Men
- Trial name
- NCT03361384
- Testing
- Alcohol
- Where
- 3 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Volatile Organic Compounds, Cancer
Cancer Diagnoses From Exhaled Breath With Na-nose
Early diagnoses of malignant tumors are pivotal for improving their prognoses. The Exhaled Breath is made up of oxygen, carbon dioxide, nitrogen, water, inert gases and volatile organic compounds (VOCs).
- Conditions
- Volatile Organic Compounds, Cancer, Diagnoses Disease
- Trial name
- NCT03967652
- Testing
- Nanomaterial-based sensors
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Thyroid Cancer, Papillary, Leptin Levels
Leptin Levels in Papillary Thyroid Cancer
The purpose of this study is to evaluate Leptin levels in females, in the setting of papillary thyroid cancer, benign thyroid nodules, and in normal females without thyroid disease.
- Trial name
- LL-PTC (NCT01659385)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Skin Cancer
In Vivo Confocal Microscopy of Cutaneous Neoplasms and Normal Skin
The purpose of this study is to investigate new non-invasive imaging techniques for the evaluation of skin lesions, as well as normal skin.
- Trial name
- NCT00588315
- Where
- 4 sites in United States
- Volunteers
- 1,889 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
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