Clinical trials: Cancer Childhood
Leukemia
Biomarkers in Tissue Samples From Patients With Acute Promyelocytic Leukemia
RATIONALE: Studying samples fo tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT01232855
- Testing
- protein expression analysis, western blotting, flow cytometry
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Cancer
MAAT For Young Adult Cancer Survivors
The goal of this clinical trial is to pilot-test a modified version of telehealth-delivered Memory and Attention Adaption Training (MAAT) that is tailored to young adult childhood cancer survivors (ages 18-39; MAAT-YS) with…
- Trial name
- MAAT-YACCS (NCT06150976)
- Testing
- MAAT-YS
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Lymphoma
Surgery Alone or With CYC VBL and PRED or CVP Alone in Stage IA or IIA Nodular Lymphocyte-Predominant Hodgkin Lymphoma
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, vinblastine, and prednisolone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- EuroNetLP1 (NCT01088750)
- Testing
- cyclophosphamide, prednisolone, vinblastine sulfate
- Where
- Germany
- Volunteers
- 225 people
- Sponsor
- Christine Mauz-Körholz
Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia
These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML.
- Trial name
- NCT01576185
- Testing
- laboratory biomarker analysis, quizartinib, sorafenib tosylate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Leukemia, Myelodysplastic Syndromes
Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome
RATIONALE: Diagnostic procedures may improve the ability to detect residual disease. PURPOSE: Clinical trial to detect the presence of residual disease in children who are receiving therapy for acute myeloid leukemia or…
- Trial name
- NCT00003790
- Testing
- polymerase chain reaction, flow cytometry
- Where
- 43 sites in United States, Australia and 1 more
- Volunteers
- 496 people
- Sponsor
- Children's Oncology Group
Mukbang
The Association Between Watching Mukbang Videos and the Appetite of Children With Cancer
The purpose of this study is to record the "Mukbang" watching behavior and appetite of children with cancer during inpatient radiotherapy and chemotherapy through intensive longitudinal study, explore their correlation, and the…
- Trial name
- NCT05493020
- Testing
- Questionnaires set
- Where
- China
- Volunteers
- 179 people
- Sponsor
- Sun Yat-sen University
Pediatric Cancer
Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)
To evaluate the ability of a multidisciplinary and multisite group, the Pediatric Evolutionary Tumor Board (pedsETB), to develop additional therapeutic strategies in patients without curative options or with suboptimal outcomes.
- Trial name
- NCT06423950
- Testing
- Peds Evolutionary Tumor Board (pedsETB)
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Leukemia
Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
Phase II trial to study the effectiveness of radiation therapy following chemotherapy in treating children with CNS relapse from acute lymphoblastic leukemia.
- Trial name
- NCT00002704
- Testing
- filgrastim, asparaginase, cyclophosphamide
- Where
- 70 sites in United States, Canada and 2 more
- Volunteers
- 156 people
- Sponsor
- National Cancer Institute (NCI)
Childhood Brain Tumors, Endocrine Disorders
Late Endocrine and Metabolic Consequences After Childhood Brain Tumor Treatment
This interventional study evaluates the late endocrine and metabolic consequences of treatment of primary brain tumors in childhood.
- Trial name
- NCT07457255
- Testing
- Endocrine and Metabolic Late Effects Assessment
- Where
- Slovenia
- Volunteers
- 12 people
- Sponsor
- Institute of Oncology Ljubljana
Fatigue
Motion for Recovery: The Impact of Gyrokinesis on Childhood Cancer-Related Fatigue.
CRF influences engagement in everyday activities, mood, sleep, social relations, school attendance, academic achievement, and quality of life .
- Trial name
- NCT07137091
- Testing
- Gyrokinesis exercise
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- MTI University
Craniopharyngioma, Obesity
Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts
KRANIOPHARYNGEOM Registry 2019 will prospectively collect and descriptively analyse data on diagnostics, treatment, and follow-up of patients with craniopharyngioma.
- Trial name
- NCT04158284
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Klinikum Oldenburg gGmbH
Leukemia, Myelodysplastic Syndromes
S9910, Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer
RATIONALE: Collecting and storing samples of blood and bone marrow from patients with cancer to study in the laboratory may help doctors learn more about diagnosing cancer and how well patients will respond to treatment.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
- Trial name
- NCT00919425
- Testing
- biologic sample preservation procedure
- Where
- 292 sites in United States
- Volunteers
- 1,294 people
- Sponsor
- SWOG Cancer Research Network
Mucositis, Pediatric Cancer
The Effect of Oral Care Protocol on Prevention of Oral Mucositis in Pediatric Cancer Patients
This study conducted to determine the effects of two oral care protocols containing sodium bicarbonate or saline solution in the prevention of oral mucositis (OM), mucositis degree, and recovery time in children with cancer.
- Conditions
- Mucositis, Pediatric Cancer, Oral Cavity
- Trial name
- NCT04586491
- Testing
- Oral care protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dokuz Eylul University
Leukemia
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Acute Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses…
- Trial name
- NCT00008190
- Testing
- aldesleukin, filgrastim, busulfan
- Where
- United States
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Pediatric Cancer
Relaxation Therapy in Pediatric Oncology
This study will look at the use of relaxation therapy in children with cancer. The study will compared patients who are current receiving treatment for their cancer and those who are currently in remission.
- Trial name
- NCT04719416
- Testing
- Guided Meditation
- Where
- United States
- Sponsor
- Geisinger Clinic
Acute Lymphoblastic Leukemia
The Association Between Asparaginase Enzyme Activity Levels and Toxicities in Childhood Acute Lymphoblastic Leukaemia in NOPHOALL 2008
Evaluation of the association between risk and severity of asparaginase associated toxicities and asparaginase enzyme activity levels in children with Acute Lymphoblastic Leukemia treated in the NOPHO-ALL 2008 protocol.
- Trial name
- NCT04187248
- Testing
- Asparaginase
- Where
- Denmark
- Volunteers
- 1,248 people
- Sponsor
- Aarhus University Hospital
Lymphoma
Monoclonal Antibody Therapy in Treating Patients With Lymphoproliferative Disorder Associated With Immunosuppression Therapy
RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00003716
- Testing
- rituximab
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Childhood Malignant Ovarian Germ Cell Tumor, Childhood Malignant Testicular Germ Cell Tumor
DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings
This research trial studies deoxyribonucleic acid (DNA) samples from younger patients with germ cell tumor and their parents or siblings.
- Conditions
- Childhood Malignant Ovarian Germ Cell Tumor, Childhood Malignant Testicular Germ Cell Tumor, Ovarian Choriocarcinoma, Ovarian Embryonal Carcinoma
- Trial name
- NCT01434355
- Testing
- Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- United States
- Volunteers
- 932 people
- Sponsor
- Children's Oncology Group
Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors
RATIONALE: Collecting and storing samples of tissue or blood from patients with cancer for study in the laboratory may help the study of cancer in the future PURPOSE: This research study is collecting and storing blood and tissue…
- Trial name
- NCT00900471
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Wake Forest University Health Sciences
Acoustic Schwannoma, Adult Anaplastic Astrocytoma
Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors
This pilot clinical trial studies gallium Ga 68-edotreotide (68Ga-DOTATOC) positron emission tomography (PET)/computed tomography (CT) in finding brain tumors in younger patients.
- Conditions
- Acoustic Schwannoma, Adult Anaplastic Astrocytoma, Adult Anaplastic Ependymoma, Adult Anaplastic Meningioma
- Trial name
- NCT02194452
- Testing
- gallium Ga 68-edotreotide, positron emission tomography, computed tomography
- Where
- United States
- Sponsor
- Sue O'Dorisio
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