Clinical trials: Cancer Colon
Colo-rectal Cancer, Colonic Neoplasms
Effect of Adding Simethicone to Split-dose Polyethylene Glycol for Bowel Preparation in a Screening Colonoscopy Setting
Colonoscopy is currently accepted as the gold standard in screening, surveillance and prevention for colorectal cancer (CRC), and therefore, its quality is a major priority.
- Trial name
- NCT03816774
- Testing
- PEG split-dose and simethicone
- Where
- Portugal
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Portuguese Oncology Institute, Coimbra
Breast Cancer Screening, Colon Cancer Screening
Bundled Cancer Screening and Genetic Services Navigation
The goal of this study is to test bundled familial cancer risk assessment + multicancer (colorectal + breast) vs. single (breast) cancer navigation, using a wait list control for colorectal cancer screening referral and…
- Conditions
- Breast Cancer Screening, Colon Cancer Screening, Genetics Predisposition
- Trial name
- NCT07228000
- Testing
- Breast cancer screening navigation, Multicancer screening navigation, Usual care genetics referral
- Where
- 2 sites in United States
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Colon Cancer
Cruciferous Vegetable Intake and Histone Status in Screening Colonoscopy Patients
This research study will assess cruciferous vegetable intake in patients presenting for screening colonoscopy and correlate intake with histone status and histone deacetylace (HDAC) expression in tissue biopsy specimens and…
- Trial name
- NCT01344330
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Colo-rectal Cancer
Safety,Usability and Compliance of Using C-Scan System for Providing Information on Colonic Polypoid Lesions and Masses
Protocol Title: Evaluation of safety, usability and subject compliance while using Check- Cap's C-Scan System for providing structural information on colonic polypoid lesions and masses Study Design: Prospective, Multi-center…
- Trial name
- C-Scan (NCT03735407)
- Testing
- C-Scan procedure
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Check-Cap Ltd.
Colorectal Cancer
Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode
The ECLIPSE (Evaluation of the ctDNA LUNAR test in an Average Patient Screening Episode) study is a prospective, observational multi-site study without randomization.
- Trial name
- ECLIPSE (NCT04136002)
- Where
- 271 sites in United States
- Volunteers
- 44,467 people, healthy volunteers welcome
- Sponsor
- Guardant Health, Inc.
Ovarian Neoplasms, Breast Neoplasms
Establishment of a Tumor Bank for Tissue Samples
Establishment of a tumor bank, consisting of tissue samples of tumor patients (benign and malign tumors) and healthy people as controls.
- Conditions
- Ovarian Neoplasms, Breast Neoplasms, Colorectal Neoplasms, Neoplasms of the Female Genitalia
- Trial name
- NCT01789229
- Testing
- Tumor tissue collection, Sampling of ascites and pleural effusion, Collecting urine samples
- Where
- 3 sites in Austria, Belgium and 1 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Colo-rectal Cancer
Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.
The primary objective of this sub-study, 2018-10B, is to collect blood specimens to assess new biomarkers for the detection of Colorectal Cancer (CRC).
- Trial name
- NCT03741166
- Testing
- Blood Sample Collection
- Where
- 37 sites in United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Cancer, Colorectal Neoplasms
Effectiveness of Modified Integrated Colorectal Cancer Screening System in Saudi Arabia
In order to encourage the population at risk to participate in colorectal cancer screening, this clustered trial intends to determine the efficacy of specific messages(Nudge), single FIT testing, and the primary care physician's…
- Trial name
- ColonCancer (NCT05785975)
- Testing
- Certain ommunications(Nudge), community-outreach(landline call), and single FIT testing
- Where
- Saudi Arabia
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Breast Cancer Risk, Ovarian Cancer Risk
Population Based Germline Testing for Early Detection and Prevention of Cancer
PROTECT-C is a research study offering genetic testing to people to see whether they have a genetic change that increases their risk of breast, ovary, bowel, and/or womb cancer.
- Conditions
- Breast Cancer Risk, Ovarian Cancer Risk, Cancer Gene Mutation
- Trial name
- PROTECT-C (NCT07498829)
- Testing
- Genetic testing for Cancer Susceptibility Genes (CSGs) (BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2, MLH1, MSH2, MSH6) and personalised breast and ovarian cancer risk
- Where
- United Kingdom
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Colorectal Cancer, Colorectal Polyps
Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?
Colonoscopy is not a perfect test. It misses a substantial number of neoplastic lesions and has some risk of missing cancer. Nearly all work on detection during colonoscopy has focused on the withdrawal phase of the examination.
- Trial name
- NCT01035775
- Testing
- Inspection during insertion, Inspection during withdrawal
- Where
- 2 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Cancer Screening
Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up Supplement
Ancillary Aim #1 We will evaluate intervention effects by comparing binary outcomes for screening (yes/no) in the primary SOS study.
- Trial name
- NCT01052922
- Testing
- 3 sample g-SENSA, 2 sample InSure, 1 sample OC-Micron
- Where
- United States
- Volunteers
- 2,260 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Colorectal Cancer, Colorectal Neoplasms
The Impact of Choice on Colorectal Cancer Screening
In May of 2021, the United States Preventive Service Task Force (USPSTF) updated their colorectal cancer (CRC) screening guidelines by recommending screening at an earlier age for average-risk adults starting at the age of 45…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Health Screening
- Trial name
- CRC45+ (NCT05275530)
- Testing
- Active FIT Choice, Active Colonoscopy Choice, Active Dual Choice
- Where
- 2 sites in United States
- Volunteers
- 20,509 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Colorectal Cancer, Colorectal Adenoma
Fecal DNA Methylation Test for Colorectal Cancer Screening
This is an observational, prospective study using fecal DNA methylation test to define the risk of suffering from advanced adenoma or colorectal cancer (CRC) compared to colonoscopy and fecal immunochemical test (FIT).
- Trial name
- NCT04823793
- Testing
- Stool DNA methylation detection
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Colon Cancer Screening, Colon Cancer Surveillance
Johns Hopkins Interactive eGuide to Colonoscopy and Ipad Office Education to Improve Colonoscopy
The investigators will attempt to improve the patient experience before colonoscopy. The investigators will provide an in-office ipad video series and an electronic web guide to help patients learn all the best ways to prepare…
- Trial name
- NCT01648504
- Testing
- eGuide to Colonoscopy and in office ipad education
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Colorectal Cancer
Colorectal Cancer Detected by 1H-NMR Spectroscopy
The hypothesis of the present study is that metabolic phenotyping of blood plasma allows to (i) discriminate between colorectal cancer patients and control subjects and (ii) identify new biomarkers for colorectal cancer.
- Trial name
- BIOCOR (NCT02364154)
- Testing
- Control group-Blood sampling, Blood sampling
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Colonoscopy
Implementation of Evidence Based Practices for Colonoscopy: The Strategies to Improve Colonoscopy Study
The purpose of this study is to compare the effect of physician education about evidence based practices for colonoscopy alone, versus physician education plus a multi-component staff implementation strategy to improve adequacy…
- Trial name
- STIC (NCT02723370)
- Testing
- Staff multi-component implementation strategy
- Volunteers
- 46,184 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Colorectal Cancer, Colorectal Polyp
Epigenetic Regulation of Colorectal Polyps and Cancer
The goal of this study is to learn about the epigenetic and genetic regulation (microRNA/mRNA) of colorectal polyps and their evolvement as polyps and to colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Polyp, Colorectal Adenoma, Colorectal Neoplasms
- Trial name
- NCT06206603
- Testing
- Intestinal biopsies, Blood sample
- Where
- Sweden
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Region Skane
Colorectal Cancer, Colorectal Adenoma
The Colorectal Cancer Chemoprevention Acceleration and Improvement Platform (CRC-CHAMP) Study
The overall goal of this study is to develop a platform for both large-scale chemoprevention trials and real-world chemoprevention studies for colorectal cancer (CRC) prevention.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT05402124
- Testing
- acetylsalicylic acid delayed release tablets, 81mg
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
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