Clinical trials: Cancer Colon
Colorectal Cancer
Comparing Interventions to Increase Colorectal Cancer Screening
The purpose of this study is to test different approaches to help people understand the purpose of colorectal cancer (CRC) screening, two screening test options available, and the barriers to screening so they can make informed…
- Trial name
- NCT03200366
- Testing
- Tailored DVD, Patient Navigation
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Indiana University
Clinical Response, Toxicity
Study of Metronomic Capecitabine and Oxaliplatin Versus XELOX in Egyptian Metastatic Colorectal Cancer Patients
Colorectal cancer (CRC) in Egypt is advanced tumors at diagnosis. Although, the dramatic increase in efficacy, reduction of mortality, and improvements in survival by the use of standard doses of chemotherapy, some CRC patients…
- Conditions
- Clinical Response, Toxicity, Survival
- Trial name
- NCT04425564
- Testing
- metronomic XELOX, Classic XELOX, Blood samples for pharmacological studies
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Colorectal Cancer, Healthy, no Evidence of Disease
Narrative or Fact-Based Videos in Increasing Colorectal Cancer Screenings in African American Communities
This randomized clinical trial studies narrative or fact-based videos in increasing colorectal cancer screenings in African American communities.
- Trial name
- NCT02100254
- Testing
- behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 1,310 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Colorectal Neoplasms
Colorectal Cancer Associated Host and Microbiome Study
Recruit of healthy, precancer and colorectal cancer patients and record necessary information of demographic and also other messages. All the volunteers were asked to provide samples including stool, blood, urine and tissues.
- Trial name
- NCT03998644
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Colonic Neoplasm
Narrow Band Imaging for Diagnosis of Proximal Serrated Polyps
Although colonoscopy is considered the gold standard for diagnosis of colonic polyps, the missed rate for colonic adenoma ranged from 15-32%.
- Trial name
- NCT01725321
- Testing
- Narrow band imaging
- Where
- China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colon Cancer, Polyps
Evaluation of Stool Tagging for Improved Patient Compliance
Computed tomography (CT) colonography has gained widespread multi-disciplinary interest as an evolving noninvasive colorectal screening examination, with the potential of improved patient compliance.
- Trial name
- NCT00124163
- Testing
- Imaging procedure of CT colonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Center for Diagnostic Imaging
Colorectal Cancer
The PRIME-CRC Trial to Promote CRC Screening in Rural Communities
The investigators will expand an existing, patient-centered, health literacy strategy to promote longer-term adherence to colorectal cancer (CRC) screening in resource-limited, rural health clinics via colonoscopy or annual fecal…
- Trial name
- NCT04313114
- Testing
- health literacy appropriate education and demonstration, shared decision making, automated call reminders or automated texts
- Where
- 3 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Screening Colonoscopy, Surveillance Colonoscopy
Study to Evaluate the Diagnostic Performance of of MAGENTIQ-COLO During Colonoscopy.
This is an international, multicenter, study to evaluate the diagnostic performance of the CADx polyp sizing modality of the MAGENTIQ-COLO.
- Trial name
- NCT06568523
- Testing
- MAGENTIQ-COLO.
- Where
- 5 sites in United States, Israel and 1 more
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Magentiq Eye LTD
Colorectal Cancer, Exercise, Aerobic
Pedaling at a Low-Moderate Intensity During Chemotherapy Administration
The purpose of this study is to evaluate the feasibility of completing a low-moderate intensity pedaling session concurrent to chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Exercise, Aerobic, Chemotherapy, Chemotherapeutic Toxicity
- Trial name
- NCT04258969
- Testing
- Pedaling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Colon Cancer
The Effect of Mentholyptus Drops on the Palatability of PEG-Electrolyte Solution
The investigators aim is to study the efficacy of mentholyptus drops in improving the palatability of PEG-electrolyte solution used in bowel cleansing for colonoscopy.
- Trial name
- NCT01541683
- Testing
- PEG solution (Fortrans®) and Mentholyptus Drops (Halls®), PEG solution (Fortrans®)
- Where
- Lebanon
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Colon Cancer
OctavaColon Cancer Blood Tests OctavaGold and OctavaSilver - Blood Tests for the Help in Diagnosis of Colon Cancer Clinical Study Protocol
The OctavaColon tests are qualitative plasma tests that are indicated to people above 18 years of age suspected with colon abnormality.
- Trial name
- NCT02066259
- Where
- 3 sites in Israel
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- Eventus Diagnostics Ltd
Gastric Cancer, Non-small Cell Lung Cancer
Clinical Study to Compare the Pharmacokinetics and Safety of Ramucirumab Injection With Cyramza ® in Healthy Male Volunteers
Ramucirumab is a biosimilar drug of CYRAMZA® produced by Chiatai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., LTD. It is a vascular endothelial growth factor receptor 2 (VEGFR-2) antagonist.
- Conditions
- Gastric Cancer, Non-small Cell Lung Cancer, Colo-rectal Cancer
- Trial name
- NCT05800418
- Testing
- Ramucirumab Injection, Ramucirumab Injection [Cyramza]
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Colorectal Cancer, Surgery
Human Blood Specimen Collection to Evaluate Immune Cell Function
Natural killer (NK) cells are leukocytes of the innate immune system and play a central role in the control of cancer metastases.
- Conditions
- Colorectal Cancer, Surgery, Perioperative Care
- Trial name
- NCT03422120
- Testing
- Natural Killer Cell Activity Assay
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Malignant Neoplasm of Large Intestine
Effectiveness of Direct-to-Patient Outreach on Colorectal Cancer Screening Within a Low Income and Diverse Population
The purpose of this study is to determine if the direct mailing of fecal occult blood testing (FOBT) kits to patients who are due for colorectal cancer screening is an effective way to improve colorectal cancer screening rates…
- Trial name
- NCT01385579
- Testing
- Care manager outreach
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Metastatic Colorectal Cancer
FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation
Single-arm, multi-centre phase II study The primary objective is to evaluate the time to failure of the strategy.
- Trial name
- OPTIPRIME (NCT03584711)
- Testing
- FOLFOX + panitumumab
- Where
- 124 sites in France, Martinique
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federation Francophone de Cancerologie Digestive
Colorectal Cancer Screening, Hepatitis C Virus
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
- Trial name
- MATCHES (NCT06745895)
- Testing
- MATCHES
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colorectal Cancer
Personal Electronic Health Records in Improving Screening Rates for Colorectal Cancer
RATIONALE: Use of a web-based risk assessment tool may help improve screening rates for colorectal cancer. PURPOSE: This randomized clinical trial is studying personal electronic health records to see how well they work in…
- Trial name
- NCT01032746
- Testing
- educational intervention, internet-based intervention, evaluation of cancer risk factors
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Harvard University
Colonoscopy, Adenomatous Polyp
A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging
The investigators hypothesize that NBI will have a high accuracy in predicting polyp histology real time during a colonoscopy by visualization of the surface mucosal and vascular patterns.
- Conditions
- Colonoscopy, Adenomatous Polyp, Neoplastic
- Trial name
- NBI (NCT00613262)
- Testing
- Narrow Band Imaging
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Colorectal Cancer, Polyp
Safety and Efficacy of the NaviAid™ G-Eye System During Colonoscopy
To evaluate the safety of using the NaviAid™ G-Eye system during Colonoscopy
- Conditions
- Colorectal Cancer, Polyp, Adenoma
- Trial name
- NCT01749722
- Testing
- NaviAid™ G-Eye procedure
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
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