Clinical trials: Cancer Colon
Colon Cancer
Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer
This is a research study to test whether two immunotherapy drugs-cemiplimab and fianlimab-can safely and effectively shrink colon tumors before surgery in people with stage II-III colon cancer that has not spread to other parts…
- Trial name
- NACho (NCT07224022)
- Testing
- Cemiplimab + Fianlimab [Fixed Dose Combination (FDC)]
- Volunteers
- 24 people
- Sponsor
- John Strickler, M.D.
Cancer of the Colon
Colorectal Cancer Screening in a Community Health Setting
This randomized controlled pilot study at the Health Annex, Family Practice \& Counseling Network (FPCN), a community clinic in Southwest Philadelphia, aimed at providing data on the feasibility of a mailed FIT approach to CRC…
- Trial name
- NCT03072095
- Testing
- Text-only, Text + Lottery
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Colorectal Cancer, Breast Cancer
Health Information Technology (HIT) Enhanced Family History Documentation and Management in Primary Care
We evaluated whether collection of risk factors to generate an electronic health record (EHR)-linked personalized health risk appraisal (HRA) for coronary heart disease (CHD), diabetes, breast and colorectal cancer (CRC) was…
- Conditions
- Colorectal Cancer, Breast Cancer, Coronary Heart Disease, Diabetes
- Trial name
- NCT01468675
- Testing
- Intervention
- Where
- United States
- Volunteers
- 6,075 people
- Sponsor
- Brigham and Women's Hospital
Bowel; Disease, Carbohydrate Absorption, Difficulty Walking
A Trial of Preoperative CHO Drinks on Postoperative Walking Capacity in Colorectal Surgery
This prospective randomized controlled study is designed to investigate whether preoperative oral carbohydrate loading improves postoperative walking performance, a surrogate indicator for overall functional recovery, in patients…
- Conditions
- Bowel; Disease, Carbohydrate Absorption, Difficulty Walking, Colorectal Neoplasms
- Trial name
- NCT01844375
- Testing
- Carbohydrate group, Control group
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mingkwan Wongyingsinn, MD
Advanced Solid Tumor, Lymphoma
Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy
Subjects who previously took part in the FT500-101 study and received allogeneic NK cell immunotherapy will take part in this long term follow-up study.
- Conditions
- Advanced Solid Tumor, Lymphoma, Gastric Cancer, Colorectal Cancer
- Trial name
- NCT04106167
- Testing
- Allogeneic natural killer (NK) cell
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Fate Therapeutics
Lung Cancer (Diagnosis), Osteochondroma
Clonal Hematopoiesis Chemotherapy and Radiation Effects Study
The goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences outcomes in people receiving chemotherapy and radiation…
- Conditions
- Lung Cancer (Diagnosis), Osteochondroma, Spitz Nevus, Solid Cancers
- Trial name
- CH CARE (NCT07675967)
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Dana-Farber Cancer Institute
Colon Cancer, Rectal Cancer
Colorectal Cancer Survivors' Needs and Preferences for Survivorship Information
We are doing this study to learn more about colon and rectal cancer survivors. We want to know if survivors want more information about life after cancer.
- Trial name
- NCT01003600
- Testing
- Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer
Impact of DietarY and LIfestyle Risk Factors on Colorectal Cancer Screening
The main purpose of our project is to construct a lifestyle score based on a short questionnaire easy to complete and to validate it among participants in mass screening for colorectal cancer in Maine and Loire department over…
- Trial name
- IDYLIC (NCT02804802)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 49,000 people
- Sponsor
- University Hospital, Angers
Breast Cancer, Colon Cancer
CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Background: The p53 gene normally helps to stop cancer cells from growing. However, when the p53 gene is mutated or damaged, cancer cells may grow unchecked.
- Conditions
- Breast Cancer, Colon Cancer, Pancreatic Cancer, Sarcoma
- Trial name
- NCT01386502
- Testing
- p53: 264-272 peptide, CT-011
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Nutrition Related Neoplasm/Cancer, Colorectal Cancer
Postoperative Diet With Hyperproteic Supplement Versus a Supplement With Imunonutrients, in Colorectal Cancer Surgery
The study is a randomized, multicentric, double-blind, controlled with active comparator, parallel groups trial, to demonstrate the non-inferiority in efficacy and therapeutic safety of the postoperative diet with…
- Conditions
- Nutrition Related Neoplasm/Cancer, Colorectal Cancer, Surgery--Complications, Site Infection
- Trial name
- NUTRICOLON (NCT04059731)
- Testing
- Nutrition supplement
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Metastatic Colorectal Cancer
CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal Cancer
HS-CA102N-103 is a Phase 2, randomized, open label study to evaluate efficacy, safety, and tolerability of CA102N combined with trifluridine/tipiracil (TAS-102) compared to bevacizumab combined with TAS-102 in subjects with…
- Trial name
- NCT06039202
- Testing
- CA102N, TAS-102, Bevacizumab
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Holy Stone Healthcare Co., Ltd
Colorectal Neoplasms, Colonic Polyp
Effectiveness of Artificial Intelligence-Assisted Colonoscopy for Adenoma Detection in Routine Clinical Practice : a Prospective Multicenter Randomized Trial
This study is a multi-center, randomized controlled trial designed to evaluate whether an artificial intelligence (AI) system can assist endoscopists to improve the detection rate of colorectal adenomas and cancers during…
- Conditions
- Colorectal Neoplasms, Colonic Polyp, Adenoma, Colorectal Cancer
- Trial name
- AI-COLOADR (NCT07307547)
- Testing
- AI-Assisted Colonoscopy
- Where
- China
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Colorectal Cancer, Hepatic Metastases
Targeted Delivery of Chemotherapy With Ultrasound and Microbublles
The oscillations of ultrasound (US) contrast agent microbubbles under their activation by US waves engender a modulation of the permeability of biological barriers amplifying hence the extravasation of drugs and/or fluorescent…
- Trial name
- SONCHIMIO (NCT03458975)
- Testing
- MRI, Perfusion CT scan, Contrast enhanced ultrasound
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Tours
Synchronous Isolated Para-aortic Lymph Node Metastasis, Colorectal Cancer
Systemic Therapy Sequenced Isolated PALND for mCRC
The study aims to estimate the efficacy and safety of systemic therapy sequenced radical surgery in treating patients with synchronous isolated para-aortic lymph node metastasis of colorectal cancer.
- Trial name
- NCT04774757
- Testing
- Para-aortic lymph node dissection
- Where
- China
- Volunteers
- 39 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Colorectal Cancer
Evaluation of the Incidence of Nausea and Vomiting in Patients With Colorectal Cancer Receiving Irinotecan-based Therapy
This is a study to determine how much nausea and or vomiting is caused by irinotecan-based chemotherapy in patients with colorectal cancer.
- Trial name
- NCT00713128
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Colorectal Cancer, Social Determinants of Health
Paired Promotion of Colorectal Cancer and Social Determinants of Health Screening
This work is an implementation science study that examines different aspects of implementing a single intervention. The intervention consists of asking community health centers to implement an outreach strategy to screen patients…
- Trial name
- NCT04585919
- Testing
- Paired Screening Intervention
- Where
- 4 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Colon Cancer Prevention
Study of QRH-882260 Heptapeptide Application in the Colon
A Phase 1B study of the efficacy of a topically-administered 7-amino acid peptide labeled with a near-infrared fluorophore Cy5 for detecting neoplastic areas of the colon is proposed.
- Trial name
- NCT03148119
- Testing
- QRH-882260 Heptapeptide, Scanning Fiber Endoscope
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Danielle Kim Turgeon
Cancer Colorectal
Evaluation of Letters Promoting Colorectal Cancer Testing
In this evaluation, 4 different versions of letters are being sent with mailers promoting colorectal cancer screening with an at-home test.
- Trial name
- NCT04548765
- Testing
- Letter, Loss Frame and Fear Appeals, Transparency
- Where
- United States
- Volunteers
- 14,644 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Colorectal Cancer
Virtual Colonoscopy Using Omnipaque as a Contrast Agent
CT colonography (CTC) is a validated screening exam for colorectal cancer. The diagnostic accuracy of CTC depends on the quality of the bowel cleansing and contrast tagging of residual stool and fluid.
- Trial name
- NCT04582500
- Testing
- Iohexol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Colorectal Cancer
Financial Incentives to Increase Colorectal Cancer Screening in Priority Populations
The investigators propose to build on the success of the Systems of Support to Increase Colorectal Cancer trial (SOS, R01CA121125, Green) and focus on disparity groups who are less likely to be current for colorectal cancer (CRC)…
- Trial name
- NCT03080701
- Testing
- Auto Mailing Plus Money, Auto Mailing Plus Lottery
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
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