Clinical trials: Cancer Of Prostate
Prostate Cancer
APACA-Apheresis/acoustophoresis and Molecular Characterization of Prostate Cancer
The goal of this clinical study is to to improve diagnosis, follow-up and treatment for patients with disseminated prostate cancer. The aim is to isolate tumour cells before image diagnostic methods find the metastases.
- Trial name
- NCT06709326
- Testing
- Apheresis, Androgen deprivation therapy, Anti androgen therapy
- Where
- Sweden
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Umeå University
Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma
Technology-Enhanced Acceleration of Germline Evaluation for Therapy, TARGET Study
This trial performs user testing of a mobile-friendly patient history collection and genetic education tool to improve healthcare providers' understanding of prostate cancer genetic testing.
- Conditions
- Biochemically Recurrent Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8
- Trial name
- NCT04447703
- Testing
- Interview, Internet Based Intervention, Survey Administration
- Where
- 5 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Prostate Cancer, Prostate Cancer Screening
Impact of PSA-based Screening on Mortality Among Men Aged 75-79: Target Trial Emulation
Opportunistic prostate-specific antigen (PSA) testing is widespread among men aged 75-79. Current American and European guidelines recommend PSA-based screening through shared decision-making if men are expected to live at least…
- Conditions
- Prostate Cancer, Prostate Cancer Screening, Prostate Cancer Screening Decision, Prostate Specific Antigen Screening
- Trial name
- NCT07206693
- Testing
- Prostate specific antigen (PSA)
- Where
- Sweden
- Volunteers
- 257,275 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Prostate Cancer Screening
The Effect of the Prostate Cancer Foundation Screening Guidelines for Black Men on Intention to Screen in Faith-based Communities
To learn about barriers to prostate cancer screening in Black, faith-based communities. Investigators will use the information collected in this study to create a prostate cancer education program that is relevant to Black men…
- Trial name
- NCT06838325
- Testing
- Prostate Cancer Screening
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer, Polygenic Risk Score
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
The goal of this clinical trial is to evaluate a screening method to detect clinically relevant prostate cancer. This clinical trial is using genetic data to determine a man's risk of cancer, together with multiparametric…
- Trial name
- PRS (NCT06398639)
- Testing
- Polygenic Risk Score (PRS)
- Where
- 5 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Adam S. Kibel, MD
Prostate Cancer
Study of 2 Different Doses of Revlimid in Biochemically Relapse Prostate Cancer
The primary objectives of the study are: To evaluate feasibility, safety and tolerance of 6 months administration of Revlimid at 5mg/day and 25mg/day, given orally in subjects with prostate cancer with evidence of biochemical…
- Trial name
- NCT00348595
- Testing
- Revlimid
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer, Prostate Cancer
Methylselenocysteine Effects on Circadian Rhythm
The primary objective of this study is to determine if vitamin supplementation with a naturally occurring dietary amino acid called organic selenium (i.e., methylselenocysteine) can restore disruption of circadian rhythm in shift…
- Trial name
- NCT01611038
- Testing
- Methylselenocysteine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Breast Carcinoma, Prostate Carcinoma
EMBRACE: Exercising Together
This phase II trial tests how well an exercise intervention, Exercising Together, works in preventing declines in physical and mental health in couples during radiation treatment for cancer.
- Trial name
- NCT06049355
- Testing
- Exercise Intervention, Biospecimen Collection, Educational Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Prostate Cancer
Trial of Community Health Worker-led Decision Coaching
Black men are disproportionately affected by prostate cancer, the most common non-cutaneous malignancy among men in the U.S. This randomized trial will evaluate the efficacy of a Community Health Worker-led decision coaching…
- Trial name
- NCT03726320
- Testing
- Education Counseling Session for PSA Screening, General Health Counseling Coaching
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Prostate Cancer
Predictors of Mental Health in Men With Prostate Cancer Undergoing a Patient Empowerment Program
Each year over 20,000 men are diagnosed with prostate cancer in Canada with the majority undergoing some form of treatment option.
- Trial name
- PC-PEP (NCT04895839)
- Testing
- Patient Empowerment Program
- Where
- 16 sites in Belgium, Canada and 3 more
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Gabriela Ilie
Cancer Survivor, Partner
Lifestyle Intervention for the Reduction of Prostate Cancer Disparities Among African Americans
This trial studies how well a lifestyle intervention works in reducing prostate cancer disparities among African American prostate cancer patients and their spouses or romantic partners.
- Conditions
- Cancer Survivor, Partner, Spouse, Stage I Prostate Cancer AJCC v8
- Trial name
- NCT04215029
- Testing
- Exercise Intervention, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
The BARCODE 1 Study (Full Study): The Use of Genetic Profiling to Guide Prostate Cancer Targeted Screening.
BARCODE 1 is a screening study designed to investigate the role of genetic profiling for targeting population prostate cancer screening.
- Trial name
- BARCODE1 (NCT03857477)
- Testing
- Genetic SNP profiling, Prostate cancer screening, MRI Scan
- Where
- United Kingdom
- Volunteers
- 4,700 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Prostate Cancer
Evaluation of Rapid T2-weighted and DWI MR Sequences Reconstructed by Deep Learning for Prostate Imaging
MR prostate exam is essential for the diagnosis, workup and follow-up of prostate cancer. It allows to detect subclinical prostate cancer following an increase in the level of PSA.
- Trial name
- DLRPRO (NCT06094322)
- Testing
- MR prostate exam
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Healthy, no Evidence of Disease, Prostate Cancer
Lycopene in Healthy Male Participants
This randomized phase I trial is studying the side effects and best dose of lycopene in healthy male participants. Chemoprevention is the use of certain drugs to keep cancer from forming.
- Trial name
- NCT00450957
- Testing
- lycopene, pharmacological study
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Malignant Brain Neoplasm, Malignant Solid Neoplasm
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers).
- Conditions
- Malignant Brain Neoplasm, Malignant Solid Neoplasm, Multiple Sclerosis, Neuroendocrine Tumor
- Trial name
- NCT06788886
- Testing
- Biospecimen Collection, Exercise Intervention, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Patient Educational Materials
Patient Educational Materials for Prostate Cancer Screening
Although the harms of screening for prostate cancer with the prostate-specific antigen (PSA) test outweigh the benefits, 560,000 Ontario men undergo PSA screening each year.
- Trial name
- NCT03222466
- Testing
- Co-created PEM
- Where
- Canada
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Adverse Reaction to Diagnostic Agents and Kits Nos
Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI
Cell-based therapies in the form of stem cell-based or immune cell-based therapies are becoming important treatment options that are either approved for clinical use or are showing promise in clinical trials.
- Trial name
- TRACK (NCT02921373)
- Testing
- 19F Cell Sense-labeled PBMC, MRI
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Gregory A. Dekaban
Prostate Cancer
Sulphate Accumulation in Prostate
This study evaluates whether a broccoli intervention (≥ 4 weeks) will result in differences in tissue sulphate levels in men scheduled for prostate biopsies.
- Trial name
- SAP (NCT02821728)
- Testing
- Dietary intervention, Normal diet
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Prostate Cancer
Effect of Androgen Deprivation Therapy on Cardiovascular Function in Prostate Cancer
The aim of this project is to determine whether androgen deprivation therapy (ADT) decreases left ventricular function in prostate cancer patients.
- Trial name
- NCT03275181
- Testing
- Transthoracic Echocardiography, Arterial blood pressure, Submaximal Exercise
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Prostate Cancer, Sexual Dysfunction
Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy
RATIONALE: Tadalafil may help prevent erectile dysfunction (ED) in patients with prostate cancer that has been treated with radiation therapy.
- Trial name
- NCT00931528
- Testing
- Tadalafil
- Where
- 192 sites in United States, Canada
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Radiation Therapy Oncology Group