Clinical trials: Cancer Pain
Pain
Ameliorating the Obstacle of Pap Smear
To reduce the procedural pain of Pap smear, this study expects to apply the peak-end rule to Pap smear by prolonging the insertion of speculum after samples are obtained from the cervix.
- Trial name
- NCT04420208
- Testing
- Modified Pap test
- Where
- Taiwan
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vulvar Cancers, Vulva Neoplasm
Needlefree Lidocaine Application for Vulvar Biopsies
The goal of this study is to compare pain during a vulvar biopsy using either the needle-free J-Tip device or the standard lidocaine shot.
- Conditions
- Vulvar Cancers, Vulva Neoplasm, Vulvar Dysplasia
- Trial name
- NCT07793552
- Testing
- J-Tip, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Pain
An Exploratory Study to Assess the Effects of JNJ-39439335 on the Relief of Pain Using a Thermal-Grill Experimental Model
This exploratory study will use a thermal-grill experimental model to assess the effects of JNJ-39439335 (50 mg, single oral dose) on the relief of pain.
- Trial name
- NCT01006304
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Postoperative Pain
Pregabalin for Postoperative Pain in Women Undergoing Breast Cancer Surgery
We hypothesize that pregabalin will decrease postoperative pain, as measured by the surrogate markers postoperative pain rating scores and postoperative opioid consumption while improving the quality of recovery following breast…
- Trial name
- NCT00785382
- Testing
- Pregabalin 150 mg
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Childhood Cancer Survivors
Pain and Sleep Disturbances in Children Living Beyond Cancer: A Case-Control Study
Children living beyond cancer (CBC) represent a unique and growing population of young people in need of long-term clinical support.
- Trial name
- NCT07120646
- Testing
- Questionnaire, actigraphy measurement and sleep diary
- Where
- 2 sites in Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cancer Patients, Cancer-related Pain
A Consensus on Opioid Prescription for Oncologic Patients in Latin America - A DELPHI Study.
As seen worldwide, cancer incidence is increasing in Latin America achieving an amount of 1.3 million new cases annually.1 In addition, it is expected that up to 70% of patients with cancer will experience pain2, one of the most…
- Trial name
- NCT04844788
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Music Therapy
Music and Symptom Relief in Radiotherapy Patient
This randomized controlled study aims to evaluate the effects of music therapy administered during radiotherapy sessions on pain, stress, and anxiety levels in cancer patients.
- Trial name
- MUSİC (NCT06993441)
- Testing
- Experimantal group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ege University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Virtual Reality Experiences for Anxiety and Pain Control
This trial studies the impact of virtual reality experiences on anxiety before surgery and pain after surgery. The goal of this study is to examine how different virtual reality experiences may help reduce anxiety and improve…
- Trial name
- NCT04759183
- Testing
- Survey Administration, Virtual Reality Game, Virtual Reality Meditation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Target Controlled Infusion, Intracranial Neoplasm
Comparison of Opioid Consumption During TCI Guided by NOL Index or Standard Care Undergoing Intracranial Tumor Surgery
In this prospective, randomized controlled study, we hypothesized that nociception level index monitoring reduced opioid administration during surgery.
- Conditions
- Target Controlled Infusion, Intracranial Neoplasm, Opioid, Nociceptive Pain
- Trial name
- NOLopioid (NCT05732896)
- Testing
- Nociception Leve Indeks
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Quality of Life
Acupuncture and Integrative Care in Gynecological Surgery
Patients undergoing surgical procedures for gynecological cancer are frequently challenged by intense anxiety prior to surgery, reflecting the accompanying uncertainty regarding the diagnosis, treatment and prognosis of their…
- Trial name
- NCT03560388
- Testing
- Acupuncture and touch/relaxation
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Low Back Pain
Subcutaneous Sterile Water Injection for Relief of Low Back Pain
To compare the effect of subcutenous sterile water injection technique with the subcutaneous saline injection technique in the degree and duration of low back pain-relieving during childbirth
- Trial name
- NCT02813330
- Testing
- Subcutaneous sterile water injection, saline injection
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Metastatic Breast Cancer, Tumor
Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor
At a median follow-up of 33 months, the combination of anastrozole and NOLVADEX (tamoxifen citrate) did not demonstrate any efficacy benefit when compared to NOLVADEX (tamoxifen citrate) therapy given alone in all patients as…
- Conditions
- Metastatic Breast Cancer, Tumor, Muscle Neoplasms, Chronic Pain
- Trial name
- NASBP-B-09 (NCT06154590)
- Testing
- Method(s)1 Attribution, Method(s)2 Attribution,
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DR. DIANE CHISESI NFS. MD. PHD.
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer
The Effect of Art Therapy on Pain, Emesis, Anxiety and Quality of Life, Breast Cancer
The research sample consisted of 60 individuals, including the intervention group (n=30) and the control group (n=30), who received treatment at the Oncology Center of Sivas Cumhuriyet University Practice and Research Hospital.
- Trial name
- NCT05666583
- Testing
- Art therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pain, Pulmonary Nodules
Effect of CYP2D6*10 Gene Mutation on Perioperative Precision Analgesia of Oxycodone in Elderly Patients
The purpose of this prospective study was to determine the effect of CYP2D6 gene polymorphism on perioperative analgesia of oxycodone in elderly patients, and to assign the CYP2D6 phenotype according to the genotype, and to use…
- Conditions
- Pain, Pulmonary Nodules, Oxycodone
- Trial name
- NCT07484867
- Testing
- oxycodone
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Liver Cancer
Efficacy of TEAS on Chronic Pain and Survival in Patients Undergoing Hepatectomy
This study is a further observation and follow-up of the patients enrolled in the registration number NCT06341270 to further evaluate the efficacy of TEAS on postoperative chronic pain, quality of life and survival rate in…
- Trial name
- NCT06406244
- Testing
- TEAS group
- Where
- China
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer
Effects of SPSIP Block on Perioperative Inflammation and TLR4 in Breast Cancer Surgery
This study will investigate whether the serratus posterior superior intercostal plane (SPSIP) block improves postoperative recovery after breast cancer surgery. Participants will be randomly assigned to one of two groups.
- Conditions
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Breast Cancer, Toll-Like Receptors
- Trial name
- SPSIP-TLR4 (NCT07843212)
- Testing
- Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mucahide Emine Fidancı Kuas
Pain, Bone Metastases
Pain Phenotyping of Patients With Bone Cancer Pain
The study aims to describe and quantify pain related to metastatic bone disease. The study will include 50 subjects with disseminated breast cancer and 20 healthy subjects.
- Conditions
- Pain, Bone Metastases, Metastatic Breast Cancer
- Trial name
- BonemetPAIN (NCT03908853)
- Where
- 2 sites in Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Uterine Fibroids, Endometriosis
AMH Levels Change During Treatment With GnRh Agonist
To evaluate the variation of AMH levels in women undergoing treatment with GnRHa, and to assess whether this variation correlates with changes in the antral and pre-antral follicle ultrasonographic count (AFC).
- Conditions
- Uterine Fibroids, Endometriosis, Endometriosis of Uterus, Pelvic Pain
- Trial name
- NCT02086279
- Testing
- GnRH analogue
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia