Clinical trials: Cancer Pains
Cancer, Neuropathy
Nutritional Supplement for Treating Chemotherapy Induced Neuropathy
Administration of a nutritional supplement containing palmitoyethanolamide, alpha lipoic acid, vitamin B12, vitamin B6 , vitamin B1, nicotinamide, magnesium, zinc, vitamin E, and superoxide of dismutase in individuals receiving…
- Conditions
- Cancer, Neuropathy, Chemotherapy Induced Pain Neuropathy, Chemotherapy-Induced Peripheral Neuropathy
- Trial name
- NCT07022938
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 71 people
- Sponsor
- Aristotle University Of Thessaloniki
Opioid Use, Opioids; Harmful Use
Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy
Chronic pain management is complex, with healthcare providers historically relying on prescribing opioid medications such as morphine.
- Conditions
- Opioid Use, Opioids; Harmful Use, Hyperalgesia, Pain, Chronic
- Trial name
- NCT04902547
- Testing
- Patient Education Workshop (PEWs), Multidisciplinary Tapering Program
- Where
- 4 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Abdominal Pain, Gastritis
MAGNET (Magnetically Controlled Capsule for Assessment of Gastric Mucosa in Symptomatic Patients)
This pilot and feasibility study will be first US study to determine if a magnetically controlled capsule (MCC) can effectively visualize the anatomy of the stomach like a more traditional upper endoscopy (EGD).
- Conditions
- Abdominal Pain, Gastritis, Gastric Ulcer, Gastric Cancer
- Trial name
- NCT04724291
- Testing
- MAGNET
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- George Washington University
Shoulder Pain, Head and Neck Cancer
Reliability and Validity of Patient Reported Outcome Measures in Head and Neck Cancer
This study will utilize Rasch analysis to study the construct validity and reliability of five shoulder-related patient-reported outcome measures in patients reporting shoulder impairment following surgery for head and neck…
- Trial name
- NCT02554968
- Testing
- Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 182 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cancer, Pain
ACCESS (Access for Cancer Caregivers for Education and Support for Shared Decision Making)
The project will test the effect of educating and supporting family caregivers of hospice cancer patients on their active participation in shared decision making in the plan of care for their patients.
- Trial name
- ACCESS (NCT02929108)
- Testing
- Facebook, ACCESS
- Where
- 3 sites in United States
- Volunteers
- 489 people
- Sponsor
- Washington University School of Medicine
Surgical Pain
Erector Spinae Plane Block Versus Caudal Epidural Analgesia
The goal of this clinical trial is to compare the analgesic effect and safety of erector spinae plane block vs caudal epidural block in paediatric population undergoing lower limb cancer surgery.
- Trial name
- NCT06815094
- Testing
- Regional analgesia either CEA or ESP
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer
Examining the Relationships Between Sleep, Fatigue, and Pain in Aromatase Inhibitor-treated Patients
Aromatase inhibitors are commonly prescribed for treatment of postmenopausal women with breast cancer. These medications can cause side effects in some women, and occasionally they can be quite bothersome.
- Trial name
- NCT01983995
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Michigan
Acute Post-operative Pain, Nerve Block
Comparison of Analgesia Efficacy of Transversus Abdominis Plane Block and Posterior Approach Quadratus Lumborum Block
Prostate cancer is the second most common cancer and the fifth in cancer-related deaths. Open radical retropubic prostatectomy is the most common surgical treatment for localized prostate cancer.
- Conditions
- Acute Post-operative Pain, Nerve Block, Prostate Cancer
- Trial name
- NCT06075498
- Testing
- transversus abdominis plane block,
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Muğla Sıtkı Koçman University
Early Gastric Cancer or Gastric Adenoma
Pilot Trial on Efficacy of Single Dose Perioperative Intravenous Dexamethasone for Pain Relief After Endoscopic Submucosal Dissection
Besides major ESD-related complications, minor adverse events after ESD are also commonly noticed. Pain is one of minor ESD-related complications. .
- Trial name
- NCT02037399
- Testing
- intravenous dexamethasone, intravenous normal saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Fatigue, Nausea and Vomiting
Nurse-Provided Care or Standard Care in Treating Patients With Pancreatic Cancer
RATIONALE: Meeting with a nurse to assess symptoms and quality of life may be more effective than standard care in treating patients with pancreatic cancer.
- Conditions
- Fatigue, Nausea and Vomiting, Pain, Pancreatic Cancer
- Trial name
- NCT00902733
- Testing
- medical chart review, questionnaire administration, fatigue assessment and management
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- City of Hope Medical Center
Abdominal Cancer
Effectiveness of Pain Management Interventions in Patients With Abdominal and Pelvic Cancer
The goal of this prospective observational study is to observe the effectiveness of pain management interventions in patients with abdominal and pelvic cancer pain.
- Trial name
- NCT07357350
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Breast Cancer
Study to Assess Effect of 8 Wks of Duloxetine Therapy on Breast Cancer Patients With Aromatase-Inhibitor Associated Pain
Many women with breast cancer who are treated with aromatase inhibitor medications develop aches and pains during treatment, and some develop numbness and tingling in their hands and feet.
- Trial name
- NCT01028352
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cancer Pain Self-management
Praxis Evaluation of a Pain Self-management Support Intervention for Oncology Patients: A Stepped Wedge Design Study
Background: Significant barriers to cancer pain management are patient-related. So far, cancer pain self-management support interventions have only been tested in strictly controlled settings of randomized controlled trials (RCT)…
- Trial name
- EvANtiPain (NCT02891785)
- Testing
- ANtiPain
- Where
- 3 sites in Austria
- Volunteers
- 153 people
- Sponsor
- University of Vienna
Breast Cancer Female
PEMF and PEC Blocks in Mastectomy Reconstruction Patients
This is a prospective randomized controlled double-blind interventional study comparing the effect of pulsed-electromagnetic field device (PEMF), pectoral interfascial block (PIB), and placebo on postoperative pain control.
- Trial name
- NCT03360214
- Testing
- Bupivacaine Hydrochloride, Pulsed Electromagnetic Field (PEMF) Device, Ropivacaine Hydrochloride
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Movement Disorders
Effects of Lymph Drainage on Patients With Axillary Web Syndrome
Effects of a physical therapy program combined with manual lymphatic drainage on shoulder pain and function, quality of life, lymphedema incidence in breast cancer patients with axillary web syndrome following axillary…
- Trial name
- NCT06438848
- Testing
- Physical therapy program, Physical therapy program with lymphedema drainage
- Volunteers
- 34 people
- Sponsor
- Taif University
Vomiting, Headache
Low Dose Versus Usual Dose Dexamethasone for Symptom Control in Children Undergoing Cranial or Craniospinal Radiation
The purpose of this study is to evaluate the effectiveness of low dose dexamethasone versus high dose dexamethasone in the treatment of radiation induced vomiting.
- Trial name
- NCT01135550
- Testing
- High dose dexamethasone, Low dose dexamethasone
- Where
- 5 sites in Canada
- Volunteers
- 25 people
- Sponsor
- The Hospital for Sick Children
Cancer, Neoplasms
Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain
Background: Cancer pain can have a very negative effect on people s daily lives. Researchers want to use machine learning to detect facial expressions and voice signals.
- Conditions
- Cancer, Neoplasms, Solid Tumors
- Trial name
- NCT04442425
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- National Cancer Institute (NCI)
Pain Management
Study to Test the Efficacy of the PRO-SELF® Plus Pain Control Program to Reduce Pain in Outpatients With Cancer
Background: Up to 64% of cancer patients experience pain, and as many as 40% of patients with pain do not receive adequate pain management.
- Trial name
- PEINCA (NCT02713919)
- Testing
- Adapted German PRO-SELF© Plus Pain Control Program
- Where
- 3 sites in Switzerland
- Volunteers
- 44 people
- Sponsor
- Elisabeth Spichiger
Metastasis
Kypho-IORT vs. EBRT in Spinal Metastases
The objective of this randomized phase III study is to test the superiority of Kypho-IORT compared to EBRT with regard of time to pain reduction in patients with painful vertebral metastases.
- Trial name
- NCT02773966
- Testing
- Kypho-IORT, EBRT
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Universitätsmedizin Mannheim
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