Clinical trials: Cancer Pains
Malignant Female Reproductive System Neoplasm
Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies
This phase IV trial studies how well liposomal bupivacaine with or without hydromorphone works in improving pain control during the first 24 hours after surgery in patients with gynecological malignancies undergoing laparotomy.
- Trial name
- NCT04258631
- Testing
- Hydromorphone, Laparotomy, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Bone Metastases, Breast Cancer
Pilot, Syndros, Decreasing Use of Opioids in Breast Cancer Subjects With Bone Mets
In patients with cancer induced bone pain, addition of Syndros will improve pain relief and decrease opioid requirement.
- Conditions
- Bone Metastases, Breast Cancer, Pain
- Trial name
- NCT03661892
- Testing
- Syndros
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Arizona
Postoperative Pain
Intrathecal Dexmedetomidine vs Midazolame
Prospective Randomized Controlled Clinical Trial to Compare Intrathecal Dexmedetomidine Versus Midazolame in Orthopedic Cancer Surgeries
- Trial name
- NCT06315634
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Cervical Cancer, Cervical Dysplasia
Coughing at Time of Cervical Biopsy
To investigate the effect of coughing as an intervention to reduce pain in colposcopy guided biopsy.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Colposcopy, Pain Sensation
- Trial name
- NCT06149598
- Testing
- Coughing at the time of biopsy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Zydolab - Institute of Cytology and Immune Cytochemistry
Head and Neck Cancer, Pain
Pain Management Smartphone Application for Patients With Stage III-IV Head and Neck Cancer Undergoing Radiation Therapy
This pilot clinical trial studies a pain management smartphone application for monitoring pain in patients with locally advanced head and neck cancer who are undergoing radiation therapy.
- Conditions
- Head and Neck Cancer, Pain, Lung Cancer, Esophageal Cancer
- Trial name
- NCT02324881
- Testing
- Telephone-Based Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Colon Neoplasm
Comparing Water Exchange, Water Immersion and Air Insufflation Methods During Colonoscopy With the Option of on Demand Sedation
This prospective, randomized controlled trial compares traditional air insufflation with water immersion and water exchange in patients undergoing colonoscopy using on demand sedation.
- Trial name
- NCT01699399
- Testing
- water immersion, water exchange, air insufflation
- Where
- Taiwan
- Volunteers
- 225 people
- Sponsor
- Dalin Tzu Chi General Hospital
Lung Cancer, Pain
Acupuncture for Post-Thoracotomy Pain
Pain after surgery for lung cancer (thoracotomy) may persist for years and require long-term analgesic use. Prior studies have shown that acupuncture reduces pain and medication use in the early post-operative period after…
- Trial name
- NCT00142532
- Testing
- Acupuncture and Questionnaires
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
PASSION - P Trial: Ph Adjusted Sulfur-Colloid, Sentinel Initiative ON Pain Trial
Patients with breast cancer scheduled to undergo sentinel lymph node mapping and biopsy will be randomly assigned to one of four treatment groups: I: (Standard of Care at WRAMC): Application of L-M-X topical anesthetic cream 4%…
- Trial name
- PassionP (NCT00940199)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Walter Reed Army Medical Center
Brain Injury, Brain Tumors
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery
Postoperative pain is prevalent after intracranial surgery. Patients undergoing craniotomy are typically managed with short acting opioids to enable early and reliable post-operative neurological exam as well as avoid the risk of…
- Conditions
- Brain Injury, Brain Tumors, Craniotomy Surgery, Pain
- Trial name
- NCT06810336
- Testing
- Remifentanil, Methadone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Advanced Cancer, Cancer Pain
Healing Gardens: Leveraging Serious Games to Deliver Accessible Pain-CBT and Pharmacologic Support for Patients With Advanced Cancer Managing Pain
This study is being done to determine the feasibility and acceptability of Healing Gardens, a standalone mobile health serious game designed to deliver pain-CBT and cancer pain education to help patients with advanced cancer…
- Conditions
- Advanced Cancer, Cancer Pain, Chronic Pain
- Trial name
- NCT07825051
- Testing
- Healing Gardens content development/refinement activities, Healing Gardens serious game
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Dana-Farber Cancer Institute
Moderate to Severe Chronic Non-cancer Pain
A Safety and Effectiveness Study of Prolonged Release Tapentadol Hydrochloride Among Filipino Patients With Moderate to Severe Chronic Non-Cancer Pain
The purpose of this study is to evaluate the safety and effectiveness of prolonged release tapentadol hydrochloride for the relief of moderate to severe chronic non-cancer pain among Filipino patients.
- Trial name
- NCT01719588
- Testing
- No intervention
- Sponsor
- Janssen Pharmaceutica
Advanced Cancer, Pain
Psychophysical Studies of Cancer Therapy Pain
The Aim of this Study is to examine the feasibility of using quantitative sensory testing procedures, widely applied to the experimental study of sensory processing in humans both with and without various pain syndromes, to now…
- Trial name
- NCT00515060
- Testing
- Sensory Tests
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- M.D. Anderson Cancer Center
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Drug Interactions
Study to Learn the Effect of Drug BAY1817080 on the Way the Body Absorbs, Distributes and Excretes Another Drug Rosuvastatin in Healthy Adult Participants
Researchers in this study want to learn how the study drug BAY1817080 interacts with another drug called rosuvastatin (brand name: Crestor) and affects the way the body absorbs, distributes and excretes rosuvastatin in healthy…
- Trial name
- NCT04252300
- Testing
- Rosuvastatin, Rosuvastatin + BAY1817080
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain
RATIONALE: An Opioid Titration Order Sheet that allows healthcare providers to adjust the dose and schedule of pain medication may help improve pain treatment for patients with cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00666211
- Testing
- educational intervention, Titrated pain management, questionnaire administration
- Where
- 11 sites in United States
- Volunteers
- 98 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Chronic Pain, Mammary Cancer
Accurate Diagnosis System for Postoperative Chronic Pain Based on fMRI
Postoperative pain is an ideal model for study on acute pain changing into chronic pain. The functional imaging of magnetic resonance can reflect the extent and character of pain exactly and the structural imaging of it can be a…
- Trial name
- NCT03022864
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Chronic Cancer Pain, Pain Management
Effectiveness of Pain Management Interventions in Patients With Chronic Cancer Pain
The goal of this observational study is to observe the effectiveness of pain management strategies in patients with chronic cancer pain presenting to pain management clinic at Aga Khan University.
- Trial name
- NCT07395999
- Testing
- Pharmacological and pain Intervention procedure
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- Aga Khan University
Uterine Fibroids, Adenomyosis
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
- Conditions
- Uterine Fibroids, Adenomyosis, Pelvic Pain, Pelvic Prolapse
- Trial name
- NCT02086344
- Testing
- PBS, TLH _adnexal preservation
- Where
- Italy
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Breast Cancer, Joint Pain
Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease
This phase I trial studies how well curcumin works in reducing joint pain in patients who are breast cancer survivors and have joint disease caused by treatment with aromatase inhibitors.
- Trial name
- NCT03865992
- Testing
- Curcumin, Nanoemulsion, Quality-of-Life Assessment
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- City of Hope Medical Center
Chronic Pain, Neuropathic Pain
Transcranial Direct Current Stimulation for Chemotherapy-Related Chronic Pain in Cancer Survivors
The goal of this clinical trial is to learn if transcranial direct current stimulation (tDCS) combined with a working-memory task can treat chronic pain and related emotional and cognitive problems after chemotherapy in adult…
- Conditions
- Chronic Pain, Neuropathic Pain, Cancer Survivors, Anxiety
- Trial name
- ONCOSTIM (NCT07912775)
- Testing
- Active tDCS with Sternberg task
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de investigación e innovación biomédica de Cádiz
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.