Clinical trials: Cancer Pains
Pain, Patient Satisfaction
Patient-Controlled Sedation in Port Implantation (PACSPI-2)
The goal of the study is to determine if patient-controlled sedation (PCS) with propofol and alfentanil reduces patient-reported pain perception during implantation of subcutaneous venous port (SVP).
- Conditions
- Pain, Patient Satisfaction, Cancer, Venous Puncture
- Trial name
- PACSPI-2 (NCT05688384)
- Testing
- Propofol + Alfentanil
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- Region Jönköping County
Analgesics, Opioid, Pain
Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain
The primary purpose of this study was to characterize the pain control achieved with long-term repeated dosing of OROS hydromorphone (slow release) in patients with chronic cancer pain and the secondary purpose was to…
- Trial name
- NCT00410787
- Testing
- OROS hydromorphone HCI (slow release)
- Volunteers
- 68 people
- Sponsor
- Alza Corporation, DE, USA
Colorectal Cancer, Postoperative Pain
Ultrasound-Guided Erector Spinae Plan Block for Colorectal Surgery
Colorectal cancer is a common and lethal disease. It still remains the third most common cause of cancer death in women and the second leading cause of death in men.
- Trial name
- NCT04313764
- Testing
- Bupivacaine Hcl 0.25% ESP block, Bupivacaine Hcl 0.25% infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Palliative Medicine, Pediatric ALL
Paediatric Palliative Care Pain Management in the Community
To describe the the barriers and facilitators experienced by carers and healthcare professionals when managing medicines for pain relief for infants, children, and young people approaching the end of life in out of hospital…
- Trial name
- PARAMOUNT (NCT04519632)
- Testing
- Qualitative study
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Pain Due to Certain Specified Procedures, Prostate Cancer
Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy
The aim of this study was to compare the pain levels in transrectal ultrasound (TRUS)-guided standard 12-core prostate biopsy (SPB) and multiparametric prostate magnetic resonance imaging (MpMRI)-guided fusion prostate biopsy…
- Conditions
- Pain Due to Certain Specified Procedures, Prostate Cancer, Biopsy
- Trial name
- NCT03859804
- Testing
- Standard transrectal 12 core biopsy, MRI- US fusion prostate biopsy (FPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 252 people
- Sponsor
- TC Erciyes University
Non-cancer Pain, Chronic Non-cancer Pain
Multidisciplinary Intervention for Non-Cancer Chronic Pain: Pilot Study
Introduction: Non-cancer chronic pain (NCCP) persists beyond the injury that caused it, affecting approximately 20% of the global population (around 1.6 billion people) and 17-18% in Spain (about 8 million people).
- Trial name
- MICNP (NCT07273084)
- Testing
- Multidisciplinary Intervention Program for Chronic Non-Cancer Pain
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Victor Ortiz Mallasen
Pain, Postoperative, Pain, Chronic
Pain and Impact of Chronic Pain on Function After Total Knee Replacements
After Institutional Review Board approval, adult patients scheduled for total knee arthroplasty (TKA) will be enrolled into the study after obtaining informed consent over a 24 month period.
- Conditions
- Pain, Postoperative, Pain, Chronic, Osteogenic Sarcoma, Knee Arthropathy
- Trial name
- NCT03032679
- Testing
- Non interventional study
- Where
- India
- Volunteers
- 139 people
- Sponsor
- Tata Memorial Centre
Cesarean Delivery, Postoperative Pain
The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery
Working Title The Effect of Intrathecal Morphine and Erector Spina Plan Block on Serum Cytokine Levels and Chronic Pain in Caesarean Section Surgery Study Description This study aims to evaluate the effects of intrathecal…
- Conditions
- Cesarean Delivery, Postoperative Pain, Cytokine Levels, Chronic Pain, Postoperative
- Trial name
- NCT06684015
- Testing
- İNTRATECHAL MORPHİNE GROUP, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara University
Bladder Cancer, Postoperative Pain Management
Retrospective Analysis of Different Quadratus Lumborum Block Techniques on Recovery Quality and Analgesic Consumption in Radical Cystectomy Patients
This retrospective observational study evaluates the effects of different Quadratus Lumborum Block (QLB) techniques on postoperative recovery and total opioid consumption in patients undergoing radical cystectomy under general…
- Conditions
- Bladder Cancer, Postoperative Pain Management, Opioid Consumption, Recovery Quality
- Trial name
- QLB-CYS (NCT06851520)
- Testing
- Anterior Quadratus Lumborum Block (QLB), Posterior Quadratus Lumborum Block (QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Namik Kemal University
Breast Cancer
Spousal Relationships and Pain in Metastatic Breast Cancer
Ecological Momentary Assessment (EMA) refers to the collection of repeated measurements of phenomena as they occur in naturalistic settings using hand-held computers.
- Trial name
- NCT00386620
- Testing
- Questionnaire, Interview
- Where
- United States
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer, Diabetes
Identifying Therapeutic Factors in an 8-Week (30 Hour) Mindfulness-Based Stress Reduction (MBSR) Program
Since it's introduction in 1979 at the University of Massachusetts Medical Center by Dr. Jon Kabat-Zinn, Mindfulness-Based Stress Reduction (MBSR) has become a respected adjunct to conventional treatment for patients suffering…
- Conditions
- Cancer, Diabetes, Hypertension
- Trial name
- mbsr (NCT01599143)
- Testing
- Teaching Mindfulness-based Stress Reduction strategies
- Volunteers
- 135 people
- Sponsor
- North York General Hospital
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Neoplasms, Bone Tissue, Pain, Intractable
Study of the Impact of the Femoral Implant "Y-strut" on Lytic Bone Metastases of the Femoral Neck (WAZA-ARY)
Bone metastases appear in many cancers. They are associated with severe pain that is refractory to standard treatment. Improving the quality of life and better pain relief is therefore an essential goal of the treatment of…
- Conditions
- Neoplasms, Bone Tissue, Pain, Intractable, Hip Fractures
- Trial name
- WAZA-ARY (NCT03887494)
- Testing
- Implantation
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Operative Pain, Acute
Comparison of Needlescopic vs. Conventional Laparoscopic Adrenalectomy for Tumor Less Than 4 cm
The investigator conduct a randomized clinical trial for the needlescopic and conventional laparoscopic adrenalectomy to assess whether mini laparoscopic adrenalectomy is better than conventional laparoscopic adrenalectomy in…
- Trial name
- NCT05675124
- Testing
- Needlescopic laparoscopic adrenalectomy, conventional laparoscopic adrenalectomy
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- National Taiwan University Hospital
Pain, Postoperative, Mastectomy
Comparison of Pain Therapeutic Effects After Benign Mastectomy
With the incremental trend of benign breast tumor, the surgical process of mastectomy was proceeded too much every day, especially in the Maternal Health Care Hospital, but whether the investigators can find another way to…
- Trial name
- COPTEAM (NCT00519246)
- Testing
- Saline, Opioid, NSAID
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Nanjing Medical University
Mucositis, Pain
Fentanyl Sublingual Spray in Treating Opioid-tolerant Cancer Patients With or Without Oral Mucositis
This was an open-label, single-dose study to assess the safety, tolerability, and absorption/distribution kinetics of a single 100 µg dose of fentanyl sublingual spray in opioid-tolerant cancer subjects, with or without oral…
- Conditions
- Mucositis, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00956254
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- INSYS Therapeutics Inc
Opioid-Induced Constipation
Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects
This purpose of this study is to evaluate the safety and effectiveness of a subcutaneous (injection beneath the skin) form of methylnaltrexone in subjects who have cancer-related pain and constipation from taking opioids.
- Trial name
- NCT00858754
- Testing
- methylnaltrexone
- Where
- 8 sites in United States, Canada and 2 more
- Sponsor
- Bausch Health Americas, Inc.
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids
This phase II trial studies whether psilocybin with psychotherapy is safe and if it works for improving chronic pain in cancer patients who require opioids to manage their pain.
- Trial name
- NCT06827054
- Testing
- Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Chronic Pain
Analgesic Efficacy of Sacral Neuromodulation for Pelvic Cancer Pain: A Preliminary Report
in this trial, we will test the analgesic efficacy of sacral neuromodulation for patients with pelvic cancer, complaining of chronic pelvic pain in comparison to medical treatment.
- Trial name
- NCT04549818
- Testing
- sacral neuromodulation
- Volunteers
- 44 people
- Sponsor
- Assiut University
Opioid-Induced Constipation (OIC)
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
The purpose of this study is to evaluate the effect and safety of NKTR-118 treatment of opioid-induced constipation in patients with non-cancer-related pain, including those patients that have inadequate response to laxative…
- Trial name
- NCT01309841
- Testing
- NKTR-118
- Where
- 117 sites in United States, Australia and 2 more
- Volunteers
- 652 people
- Sponsor
- AstraZeneca
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