Clinical trials: Cancer Patient
Glioma
Glioma Patients Registry Based on Radiological, Histopathological and Genetic Analysis
This prospective study aims to collect clinical, radiological, pathological, molecular and genetic data including detailed clinical parameters, MR and histopathology images, molecular pathology and genetic sequencing data.
- Trial name
- NCT04220424
- Testing
- MR and Histopathology images based prediction of molecular pathology and patient survival
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Prostate Cancer
A Randomized Controlled Trial to Promote Physician-Patient Discussion of Prostate Cancer Screening
Prostate cancer is the most common type of cancer among men. It is also the second leading cause of cancer-related death among men.
- Trial name
- NCT00208988
- Testing
- Educational handout about prostate cancer screening, Simple cue for patient to talk to doctor
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Emory University
Lung Nodule
Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients
Low-dose computed tomography (LDCT) is recommended for early-stage lung cancer screening. However, it is often difficult to determine indolent lesions from more aggressive tumors without an invasive intervention or prolonged…
- Trial name
- NCT03685669
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Microbiota in Patients With Urinary Bladder Carcinoma in Urine and Cancer Tissues
Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Tissues From Egyptian Male Patients and Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Cancer.
Microbes inhabiting the urinary tract that are playing an important role in maintenance of health and the development of diseases and bladder cancer. There is correlation between initiation of bladder cancer and microbes.
- Trial name
- Cancer bladder (NCT06289270)
- Where
- 2 sites in Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Breast Neoplasms, Circulating Tumor Cells
Detection of Circulating Tumor Cells in Breast Cancer Patients Using a Novel Microfluidic and Raman Spectrum Device
Circulating tumor cells (CTCs) in peripheral blood originate from breast cancer (primary and metastatic lesions) shedding. Utilization of CTCs as novel and noninvasive tests for diagnosis confirmation, therapy selection, and…
- Trial name
- NCT04239105
- Testing
- Microfluidic and Raman spectrum
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Brain Cancer, Glioma
Experience of Brain Tumor Caregivers
The objective of this study is to explore the experience of informal caregivers of patients with a primary brain tumor, identifying elements and themes of the caregiving experience specific to this population of caregivers.
- Trial name
- NCT00352820
- Testing
- Interview, Questionnaire
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Triple Negative Breast Cancer
Correlation Between TILs and Blood Cell Counts in Triple Negative Breast Cancer Patients
The PERCEPTION study aims to assess the correlation between blood cell counts (Leucocytes, Neutrophils, Lymphocytes, Platelets, NLR (Neutrophil-to-Lymphocyte Ratio) and PLR (Platelet-to-Lymphocyte Ratio)) and Tumor Infiltrating…
- Trial name
- PERCEPTION (NCT04068623)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Jean Perrin
Lung Cancer
Support Needs and Preferences of Family Caregivers of Lung Cancer Patients
This study is being done to learn what the needs are in relation to the family members. Some family members seek counseling; others do not.
- Trial name
- NCT00967083
- Testing
- Questionnaires/Interviews
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
In Vitro Fertilization, Polycystic Ovary Syndrome
Comparative Study of Long-acting and Short Acting Triptorelin in PCOS Patients Who Underwent IVF/ICSI
To test whether long-acting Triptorelin on pituitary down-regulation can improve the clinical pregnancy rate and reduces the incidence of ovarian hyperstimulation syndrome (OHSS) in infertile high-risk patients with polycystic…
- Trial name
- NCT02477566
- Testing
- Long-acting Triptorelin, Short-acting Triptorelin
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanjing University
Melanoma
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)
Melanoma is an immune-modulated malignancy and immune checkpoint modulators which inhibit PD-1 function (pembrolizumab, nivolumab) have demonstrated clinical efficacy as treatment for patients with stage IV melanoma.
- Trial name
- NCT03241927
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Nina Bhardwaj
Quality of Life
Acupuncture and Integrative Care in Gynecological Surgery
Patients undergoing surgical procedures for gynecological cancer are frequently challenged by intense anxiety prior to surgery, reflecting the accompanying uncertainty regarding the diagnosis, treatment and prognosis of their…
- Trial name
- NCT03560388
- Testing
- Acupuncture and touch/relaxation
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Metastatic Solid Tumors, Advanced Non-squamous Non-small-cell Lung Cancer
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants With Advanced or Metastatic Solid Tumors With KRAS Mutations or Amplification
This is a first-in-human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BGB-53038 as…
- Conditions
- Metastatic Solid Tumors, Advanced Non-squamous Non-small-cell Lung Cancer, Advanced Colorectal Cancer, Advanced Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT06585488
- Testing
- BGB-53038, Tislelizumab, Cetuximab
- Where
- 17 sites in United States, Australia and 3 more
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- BeOne Medicines
Gastric Cancer
Circulating Exosomes As Potential Prognostic And Predictive Biomarkers In Advanced Gastric Cancer Patients ("EXO-PPP Study")
Exosomes are formed by inward budding of late endosomes, producing multivesicular bodies (MVBs), and are released into the environment by fusion of the MVBs with the plasma membrane.
- Trial name
- EXO-PPP (NCT01779583)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital Miguel Servet
Neoplasms, Hematologic Neoplasms
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
This study will collect biological samples for use in research experiments aimed at better understanding the clinical features of certain diseases.
- Conditions
- Neoplasms, Hematologic Neoplasms, Healthy Volunteers
- Trial name
- NCT00071045
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Caregivers, Cancer
An Exploratory Study of Caregiver Burden Among Family Caregivers of Patients With Cancer
This study will look at caregiver burden and the coping behavior of caregivers of patients with cancer. Through this study, the investigators will identify the relationship between cognitive dysfunction (measured as a proxy…
- Trial name
- NCT03069105
- Testing
- Questionnaire
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Saint John's Cancer Institute
Gynecologic Cancer
Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care
Although brachytherapy is an effective treatment modality for gynecological cancer, a significant proportion of patients develop late treatment-related vaginal toxicity, negatively impacting their quality of life and limiting…
- Trial name
- BrachDEP (NCT04707937)
- Testing
- Online education, Regular standard of care education
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Non-melanoma Skin Cancer
Post-market Multi-Center RETRO-Prospective Study to Assess Long-term Clinical Outcomes NMSC Patients Treated With eBx
The purpose of this retrospective-prospective study is to evaluate lesions after treatment for BCC or SCC NMSC in order to gain a better understanding of the durability of the treatment, and risk of late toxicities for this…
- Trial name
- NCT05257486
- Testing
- Xoft eBx
- Where
- 2 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Xoft, Inc.
Urological Nursing
Effect of Heat Aplication to Patients During Cystoscopy Procedure
This randomized controlled study was planned to determine the effect of hot application, which is one of the non-pharmacological methods that can be applied to reduce pain during the Rigid Cystoscopy procedure, on pain, anxiety…
- Trial name
- NCT06699173
- Testing
- Heat ped
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Emine Karakaya
Carcinoma of Unknown Primary
Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP)
Abbreviated Title: Pembrolizumab in Patients with Poor-Prognosis Carcinoma of Unknown Primary Site (CUP) Trial Phase: 2 Clinical Indication: Treatment naïve patients with poor prognosis carcinoma of unknown primary site Trial…
- Trial name
- CUP (NCT03391973)
- Testing
- Pembrolizumab Injection
- Where
- 3 sites in Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Advanced Cancer
Patient and Family Decision Making in the Palliative Care Setting
The goal of this research study is to learn about any differences in certain health-related preferences between patients with cancer and their families.
- Trial name
- NCT00682994
- Testing
- Interview, Questionnaire
- Where
- 4 sites in United States, Argentina and 2 more
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
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