Clinical trials: Cancer Patients With Cancer Pain
Chemotherapy-induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Use of PEA and Scutellaria in Synergy With Therapeutic Exercise in Chemotherapy-induced Peripheral Neuropathy (CIPN): a Clinical Trial
This study aims to find out if taking specific dietary supplements (PEA and Scutellaria) along with therapeutic exercise can help reduce nerve pain and damage caused by chemotherapy.
- Trial name
- NCT07352514
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Breast Cancer, Radiation Therapy Patient
A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer
The goal of this interventional study is to to evaluate the effectiveness and acceptability of a focused upper body massage when offered after radiation treatments to participants diagnosed with breast cancer.
- Trial name
- NCT07447700
- Testing
- upper body massage
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Carpal Tunnel Syndrome
Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome
The purpose of this study is to evaluate the analgesic efficacy and safety of the lidocaine patch 5% compared to placebo in patients with moderate to severe pain associated with carpal tunnel syndrome.
- Trial name
- NCT00266214
- Testing
- lidocaine patch 5%
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Cancer Pain, Quality of Life
Meditation With Virtual Reality for Cancer Pain Relief in the Pain Therapy and Palliative Care Service
Cancer is a disabling, challenging and growing global disease. Although early diagnosis and adequate treatment of oncological disease have been developing rapidly, a large part of the population remains without access to…
- Conditions
- Cancer Pain, Quality of Life, Palliative Medicine
- Trial name
- NCT06328751
- Testing
- Case group, Active control group, Passive control group
- Where
- Brazil
- Volunteers
- 129 people
- Sponsor
- Emily Santos Montarroyos
Cancer Pain
Gene Transfer for Cancer Pain
The primary purpose of this study is to examine the safety of NP2 (a nonreplicating HSV-based vector expressing enkephalin) in patients with cancer pain. The secondary purpose is to evaluate efficacy.
- Trial name
- NCT00804076
- Testing
- NP2
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Diamyd Inc
Advanced Malignant Neoplasm, Pain
Rectal Administration of Opioids Using the Macy Catheter in Reducing Pain in Patients With Advanced Cancer
This trial studies how well rectal administration of opioids using the Macy catheter works in reducing pain in patients with cancer that has spread to other anatomic sites or is no longer responding to treatment.
- Trial name
- NCT03592459
- Testing
- Macy Catheter, Pain Therapy, Questionnaire Administration
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Cancer
Endoscopic Pancreatic Duct Stenting for Relief of Obstructive Pain in Patients With Pancreatic Cancer
This research is being done to assess the effects of pancreatic duct stenting on relief of obstructive pain (pain due to outflow obstruction of main pancreatic duct) caused by pancreatic cancer.
- Trial name
- NCT01895790
- Testing
- Pancreatic Duct Stent Placement
- Where
- United States
- Sponsor
- Johns Hopkins University
Lymphedema, Breast Cancer
Effects of Extracorporeal Shock Wave Therapy (ESWT) and Low Intensity Laser Therapy (LLLT) Added to Complete Decongestive Therapy (CDT) on Extremity Volume, Pain Intensity, Functional Status and Quality of Life in Patients With Postmastectomy Stage 2 Lymphedema
This study aimed to comparatively investigate the effects of ESWT and LLLT added to conventional CDT (which is the standard treatment for breast cancer-related lymphedema) on patients' limb volume, pain intensity, functional…
- Trial name
- NCT06415396
- Testing
- Complete Decongestive Therapy, ESWT, LLLT
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Vertebral Fracture, Multiple Myeloma
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.
Patients with newly diagnosed or known multiple myeloma with newly diagnosed vertebral lesion(s) will be invited to participate in a cross-sectoral randomized controlled trial.
- Trial name
- NCT04533217
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Spine Centre of Southern Denmark
Chronic Non-cancer Pain, Patient Education as Topic
Scool of Pain (SchooP): A Way to Create Value in Healthcare?
BACKGROUND: Chronic non-cancer pain (CNCP) is a disabling condition with radical consequences. Magic fix-it solutions do not exist. CNCP is a condition for life, calling for healthcare services supporting its management.
- Trial name
- SchooP (NCT07363746)
- Testing
- Pain school intervention
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain
Long-term Opioid Therapy, Misuse and Mortality in Patients With Chronic Non-cancer Pain in Germany
Among patients receiving opioids for noncancer pain, recent research in North America showed a strong association between doses and opioid-related mortality, especially at dosages exceeding thresholds recommended in recent…
- Trial name
- NCT03778450
- Testing
- Analgesics, Opioid, Non-Opioid Analgesic
- Where
- Germany
- Volunteers
- 3,232 people
- Sponsor
- LinkCare GmbH
Pain, Unspecified Adult Solid Tumor, Protocol Specific
Massage Therapy in Treating Patients With Cancer Pain
RATIONALE: Massage therapy may help lessen pain caused by cancer. PURPOSE: This randomized phase II trial is studying how well massage therapy works in treating patients with cancer pain.
- Trial name
- NCT00082290
- Testing
- massage therapy, visit with a volunteer, period of quiet time
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer Pain, Opioid Use
Psychological Intervention Using Smartphone Technology to Alleviate Malignant Pain
The purpose of this study is to develop and pilot test a novel medical intervention (STAMP+CBT app) that will help patients track their pain, mood, opioid use and side effects while delivering tailored education and…
- Conditions
- Cancer Pain, Opioid Use, Cognitive Behavior Therapy
- Trial name
- STAMP+CBT (NCT05774197)
- Testing
- Cognitive Behavioral Therapy for pain
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Oklahoma
Postmenopausal, Breast Cancer
Acupressure for Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Patients With Breast Cancer
This is a randomized, double-blinded trial of self-acupressure to examine the effect of treatment on aromatase inhibitor (AI)-associated musculoskeletal symptoms (AIMSS) in postmenopausal women with breast cancer.
- Trial name
- NCT06228768
- Testing
- Acupressure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Colorectal Cancer
Phase II Study of Minocycline for Reducing Symptom Burden in Colorectal Patients
The goal of this clinical research study is to learn if minocycline can reduce numbness, pain, and/or loss of motor function in patients with colorectal cancer. In this study, minocycline will be compared to a placebo.
- Trial name
- NCT01906008
- Testing
- Minocycline, Questionnaires, Sensory Test
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Pain
Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients
This study will evaluate whether crushed EMBEDA capsules induce clinical opiate withdrawal signs and symptoms in opioid-dependent patients with chronic non-cancer pain who are stabilized on EMBEDA.
- Trial name
- NCT01100437
- Testing
- EMBEDA™ (morphine sulfate/naltrexone hydrochloride) crush, EMBEDA™ (morphine sulfate/naltrexone hydrochloride) whole
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Pfizer
Cancer
Efficacy and Safety of Intranasal Fentanyl in the Treatment of Breakthrough Pain (FT-018-IM)
Primary objectives: To confirm the efficacy of intranasal fentanyl titrated to doses 50, 100 or 200 µg for treatment of breakthrough pain (BTP) in cancer patients To establish long-term safety of treatment with intranasal…
- Trial name
- NCT00362583
- Testing
- Fentanyl
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nycomed
Resectable Colorectal Carcinoma, Resectable Digestive System Carcinoma
Acupuncture for the Management of Postoperative Pain in Patients With Pancreatic or Colorectal Cancer Undergoing Surgery
This trial investigates how well acupuncture works for the management of pain after surgery in patients having open colorectal or pancreatic surgery. Acupuncture may help to reduce postoperative symptoms including pain.
- Conditions
- Resectable Colorectal Carcinoma, Resectable Digestive System Carcinoma, Resectable Pancreatic Carcinoma
- Trial name
- NCT04560712
- Testing
- Acupuncture Therapy, Best Practice, Questionnaire Administration
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Lymph Node Dissection
Comparison of Serratus Posterior Superior Intercostal Plane Block and Rhomboid Intercostal Block in Patients Undergoing Breast Cancer Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) and Rhomboid Intercostal Block in patients undergoing Breast Cancer Surgery With…
- Conditions
- Breast Cancer, Lymph Node Dissection, Postoperative Pain, Mastectomy
- Trial name
- SPSIP-RIB (NCT07536867)
- Testing
- Serratus posterior superior intercostal plane block, Rhomboid intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Laparoscopic Colorectal Resection Due to Cancer
The Effects of Optimizing Post-operative Pain Management With Multi Modal Analgesia on Immune Suppression and Oncologic Outcome in Patients Undergoing Laparoscopic Colorectal Surgery
Traditionally, pain control methods based on narcotic analgesics have been used to control severe pain after surgery, but this has resulted in side effects such as vomiting, constipation, dizziness, mental confusion due to drugs…
- Trial name
- NCT03462836
- Testing
- IV ketamine/lidocaine/IV PCA apply, IV PCA only apply
- Where
- South Korea
- Sponsor
- Yonsei University