Clinical trials: Cancer Pelvis
Cervical Cancer
Chemotherapy and Pelvic Hypofractionated Radiation Followed by Brachytherapy for Cervical Cancer
The main goal of this trial is to assess the safety and response rate to concomitant chemotherapy and external hypofractionated radiotherapy followed by brachytherapy in patients with clinical stage III cervical cancer.
- Trial name
- NCT04070976
- Testing
- Hypofractionated therapy, Standard therapy
- Where
- Mexico
- Volunteers
- 82 people
- Sponsor
- National Institute of Cancerología
Cervical Cancer
Panitumumab, Cisplatin, and Pelvic Radiation Therapy in Treating Patients With Stage IB, Stage II, or Stage III Cervical Cancer
RATIONALE: Monoclonal antibodies, such as panitumumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT01158248
- Testing
- panitumumab, cisplatin, brachytherapy
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University Innsbruck
Cervical Carcinoma, Endometrial Carcinoma
Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic Cancer
The study investigates whether certain characteristics of gynecological cancer can help researchers predict how well a patient recovers from surgery to remove the lower colon, rectum, and bladder, and create openings through…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Malignant Female Reproductive System Neoplasm, Vaginal Carcinoma
- Trial name
- NCT00791635
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer Cervix
Tomotherapy vs Conventional Radiation for Adjuvant Pelvic RT in Ca Cervix
The study tests Tomtherapy based Image Guided Radiation against conventional radiation techniques for it's ability to reduce long term small bowel toxicity.
- Trial name
- PARCER (NCT01279135)
- Testing
- Conventional Radiation, Tomotherapy based IGRT
- Where
- India
- Volunteers
- 300 people
- Sponsor
- Tata Memorial Hospital
Pelvic Tumor
A Positioning Navigation Template for Assisting the Placement of Modular Hemipelvic Endoprostheses for Patients Undergoing Pelvic Bone Tumor Resection.
Background: Acetabular reconstruction in situ after extensive pelvic resection is technically challenging because the significant loss of bone stock and bony landmarks.
- Trial name
- NCT04980729
- Testing
- Acetabular reconstruction after tumor resection.
- Volunteers
- 36 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Thoracic Neoplasm, Pelvic Neoplasm
Oncologic Therapy Support Via Means of a Dedicated Mobile App
The present single-center prospective exploratory study, conducted at Heidelberg University Hospital, assesses the feasibility of introducing a concept for additional patient care based on a mobile application for patients…
- Conditions
- Thoracic Neoplasm, Pelvic Neoplasm, Radiotherapy; Complications, Oncologic Disorders
- Trial name
- OPTIMISE-1 (NCT03168048)
- Testing
- mobile application
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Lymphoma, Small Intestine Cancer
Irinotecan in Treating Patients With Solid Tumors or Lymphoma Who Have Abnormal Liver or Kidney Function or Who Have Received Radiation Therapy to the Pelvis
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Irinotecan may be effective in treating patients with abnormal liver or kidney function or who have received…
- Conditions
- Lymphoma, Small Intestine Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00003368
- Testing
- irinotecan hydrochloride
- Where
- 45 sites in United States
- Sponsor
- National Cancer Institute (NCI)
Male, Stroke
Pelvic Floor Muscle Training(PFMT) on Lower Urinary Tract Symptoms (LUTS) in Men With Stroke
The aim of this study is to evaluate the effect of pelvic floor muscle training (PFMT) on Lower Urinary Tract Symptoms (LUTS) in men after stroke.
- Conditions
- Male, Stroke, Urinary Incontinence
- Trial name
- NCT01042249
- Testing
- Pelvic Floor Muscle training
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Cervical Cancer, Stage IIB, Cervical Cancer Stage IIIA
Clinical Trial of Laparoscopic Pelvic and Para-aortic Lymphadenectomy and Uterine Blood Vessel Blocking for Precision Diagnosis and Treatment in Advanced Cervical Cancer
Cervical cancer is the most common reproductive malignancy in developing country. Due to local invasion, radical hysterectomy cannot be performed in advanced cervical cancer (FIGO IIB - IVA) , so that radiation combined with…
- Conditions
- Cervical Cancer, Stage IIB, Cervical Cancer Stage IIIA, Cervical Cancer Stage IIIB, Cervical Cancer, Stage IVA
- Trial name
- NCT02950350
- Volunteers
- 50 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Venous Thromboembolism, Deep Vein Thrombosis
Screening for Occult Malignancy in Patients With Idiopathic Venous Thromboembolism
Blood clots in leg veins (deep vein thrombosis) or lung arteries (pulmonary embolism) that happen for no reason (i.e. unexplained) are both called "unprovoked venous thromboembolism" (VTE).
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- SOME (NCT00773448)
- Testing
- Comprehensive computed tomography of the abdomen/pelvis, Limited Malignancy Screening
- Where
- 9 sites in Canada
- Volunteers
- 862 people
- Sponsor
- Ottawa Hospital Research Institute
Cancer, Pelvic Floor Dysfunction
Pelvic Floor Dysfunction in Cancer Survivors.
Introduction: Pelvic floor dysfunctions (PFD) represent a major public health problem manifested through lower urinary tract symptoms (LUTS), anorectal and sexual dysfunction.
- Trial name
- NCT03979755
- Testing
- Application of questionnaires
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Sunitinib as Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Transitional Cell Cancer
RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- NCT00792025
- Testing
- sunitinib malate
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Institut Curie
Ovarian Cancer (OvCa)
Rectosigmoid Lesion Excision vs. Resection: A Non-Inferiority Randomized Comparison in Advanced Ovarian Cancer
Colorectum is the most common site of metastasis in ovarian cancer. Regarding intestinal surgery, there is controversy over whether to choose bowel resection or tumor removal, and currently, there are no prospective randomized…
- Trial name
- RSEnTrail (NCT07616310)
- Testing
- Rectosigmoid Lesion Excision +tumor cell debulking surgery, Rectosigmoid Resection +tumor cell debulking surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Prostate Cancer, Lymph Node Metastases
Use of Indocyanine Green During Pelvic Lymph Node Dissection in Prostate Cancer.
Standard treatment of local or locally advanced prostate cancer is radical prostatectomy (RRP) surgery. During RRP in certain patients extended lymph node dissection (ELND) is recommended.
- Trial name
- NCT04882618
- Testing
- Indocyanine green
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Rectal Cancer Recurrent
Pencil Beam Proton Therapy for Pelvic Recurrences in Rectal Cancer Patients Previously Treated With Radiotherapy
Study design: A prospective phase II, non-randomized observational study of dose-escalated pencil beam proton therapy re-irradiation for pelvic recurrences from rectal cancer.
- Trial name
- ReRad II (NCT04695782)
- Testing
- Pencil beam proton radiotherapy
- Where
- Denmark
- Volunteers
- 65 people
- Sponsor
- University of Aarhus
Urogenital Cancer, Lower Limb Lymphedema
Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer
After the treatment of urogenital cancer, a person may develop lymphoedema of the leg(s) and/ or midline region. Clinical symptoms include abnormal tissue swelling, sensation of limb heaviness, erythema, pain, and impaired limb…
- Conditions
- Urogenital Cancer, Lower Limb Lymphedema, Nocturia, Nocturnal Polyuria
- Trial name
- UroLymph (NCT05300308)
- Testing
- usual care
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Palliative Care
Radiotherapy in Palliation of Advanced Pelvic Cancer
The study wants to define the safety and efficacy of a short-course radiation therapy in patients with symptomatic advanced pelvic cancer.
- Trial name
- NCT03947268
- Testing
- Short course radiotherapy
- Volunteers
- 25 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Surgery--Complications, Pelvic Cancer
Reconstruction in Extended MArgin Cancer Surgery
Advanced pelvic cancers are uncommon, with treatment being challenging. Around 4000 patients every year need treatment in the UK. Cancers can involve multiple organs and often need radiotherapy and chemotherapy before surgery.
- Conditions
- Surgery--Complications, Pelvic Cancer, Abdominal Cancer, Quality of Life
- Trial name
- REMACS (NCT05219058)
- Testing
- Biological mesh reconstruction, Myocutaneous flap reconstruction, Primary closure reconstruction
- Where
- 18 sites in United Kingdom
- Volunteers
- 236 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Cancer of Pancreas, Cancer of Pelvis
Daily Imaging, Target Identification, and Simulated Computed Tomography-Based Stereotactic Adaptive Radiotherapy Workflow in a Novel Ring Gantry Radiotherapy Device
The investigators propose here to evaluate the feasibility of a novel cone-beam CT (CBCT)-guided online adaptive radiotherapy (ART) workflow on the Halcyon device.
- Conditions
- Cancer of Pancreas, Cancer of Pelvis, Cancer of Abdomen, Cancer of Thorax
- Trial name
- NCT04008537
- Testing
- Ring gantry kV-CBCT combined with linear accelerator
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Washington University School of Medicine
Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter, Recurrent Urethral Cancer
Arsenic Trioxide in Treating Patients With Urothelial Cancer
Phase II trial to study the effectiveness of arsenic trioxide in treating patients who have recurrent cancer of the bladder or urinary tract.
- Conditions
- Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter, Recurrent Urethral Cancer, Transitional Cell Carcinoma of the Bladder, Ureter Cancer
- Trial name
- NCT00009867
- Testing
- arsenic trioxide
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Cancer Institute (NCI)