Clinical trials: Cancer Related Cognitive Impairment
Cancer Related Cognitive Impairment, Breast Cancer Survivor
The Computerized Retraining and Functional Treatment - Group Intervention
The goal of this clinical trial is to examine the efficacy of a novel, remotely-applied group intervention, Cognitive Retraining and Functional Treatment Group (CRAFT-G), designed to improve cognitive function, mental health and…
- Trial name
- CRAFT-G (NCT07591857)
- Testing
- CRAFT-G, CCT
- Where
- Israel
- Volunteers
- 48 people
- Sponsor
- Hadassah Medical Organization
Breast Cancer, Cognitive Dysfunction
Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
This study will test the preliminary efficacy of transcranial direct current stimulation (tDCS) to improve fatigue and cognition in women with a history of breast cancer and persistent fatigue.
- Conditions
- Breast Cancer, Cognitive Dysfunction, Fatigue
- Trial name
- NCT03143894
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chemotherapy-Related Cognitive Impairment, Healthy
Telerehabilitation Cognitive Impairments Following Chemotherapy Usability Study
Develop a game-based upper-extremity motor and cognitive rehabilitation system using custom and adaptable virtual reality simulations.
- Trial name
- TCIFCU (NCT04839588)
- Testing
- Usability study
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bright Cloud International Corp
Chemotherapy-related Cognitive Dysfunction
Telehealth and Memory Study
The overall purpose of this trial is to confirm the efficacy of Memory and Attention Adaptation Training (MAAT), a cognitive-behavioral therapy (CBT) for treatment of chemotherapy-related cognitive dysfunction among (female or…
- Trial name
- TAMS (NCT04586530)
- Testing
- Memory and Attention Adaptation Training (MAAT), Supportive Therapy (ST)
- Where
- 2 sites in United States
- Volunteers
- 194 people
- Sponsor
- University of Pittsburgh
Cancer-related Cognitive Impairment, Oncology
Effects of a Cognitive Training Program on Chemotherapy-induced Cognitive Impairment (Chemobrain) in Breast Cancer Patients Undergoing Active Treatment
Introduction: Given the increase in breast cancer survival rates, resulting from technological and biomedical advancements, it is essential to conduct an exhaustive study of the secondary symptoms associated with the oncological…
- Conditions
- Cancer-related Cognitive Impairment, Oncology, Breast Cancer, Cognitive Training
- Trial name
- NCT06686823
- Testing
- Health Education Program, Cognitive Training Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Breast Cancer
Cognitive Training and Exercise for Women With Breast Cancer and Cognitive Impairment
Chemotherapy-related cognitive impairment is a prevalent and distressing condition among breast cancer survivors, adversely affecting memory, attention, and overall cognitive function, thereby diminishing quality of life.
- Trial name
- CHEMO-CogEx (NCT07017530)
- Testing
- Cognitive training, Psychoeducational therapy
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Universidad de Extremadura
Cancer-related Cognitive Difficulties, Cancer-related Problem/Condition
Modafinil to Improve Fatiguability
Cancer-related fatigue (CRF) and cancer-related cognitive impairment (CRCI) are among the most commonly reported disabling symptoms experienced by patients with advanced cancer.
- Conditions
- Cancer-related Cognitive Difficulties, Cancer-related Problem/Condition, Fatigue
- Trial name
- MODIFY (NCT05333250)
- Testing
- Modafinil
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Cancer, Cognitive Impairment
Digital Intervention Targeting Cancer-related Cognitive Impairments
Cognitive deficits are frequently reported following cancer treatment and can significantly impact daily functioning. These cognitive impairments often persist for years after cancer treatment.
- Trial name
- NCT06693102
- Testing
- Digital intervention targeting cancer-related cognitive impairments, Crossword and sudoku taks
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital
Brain Metastases, Brain Metastasis
Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases
Background: Cognitive symptoms are common and often severe in patients with brain metastases, significantly impacting their quality of life and ability to manage cancer care.
- Trial name
- NCT07355348
- Testing
- Cognitive Stepped Care Program (CSCP)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University Health Network, Toronto
Cognitive Impairment, Mild
Telerehabilitation Cognitive Impairments Following Chemotherapy Feasibility Study
Develop a game-based upper-extremity motor and cognitive rehabilitation system using custom and adaptable virtual reality simulations on a wearable device enhanced with biosensors.
- Trial name
- TCIFCF (NCT04972019)
- Testing
- Telerehabilitation Experimental Group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Bright Cloud International Corp
Head and Neck Cancer, Body Image Disturbance
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be randomized to BRIGHT (a brief video tele-cognitive behavioral therapy…
- Conditions
- Head and Neck Cancer, Body Image Disturbance, Body Image, Survivorship
- Trial name
- BRIGHT (NCT05442957)
- Testing
- BRIGHT, Attention Control
- Where
- 5 sites in United States
- Volunteers
- 180 people
- Sponsor
- Medical University of South Carolina
Depressive Symptoms, Cognitive Impairment
Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer (ONCODEP)
The goal of this clinical trial is to test a home-delivered intervention that combines Non-Invasive Brain Stimulation techniques (transcranial direct and alternating current stimulation -tDCS and tACS-) and Online Cognitive…
- Trial name
- ONCODEP (NCT06053775)
- Testing
- Transcranial Direct Current Stimulation, Transcranial Alternating Current Stimulation, Online Cognitive Training
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- University of Santiago de Compostela
Hematopoietic Stem Cell Transplantation, Breast Cancer
Treating Cancer-Related Fatigue Through Systematic Light Exposure
Cancer related fatigue (CRF) - a persistent sense of exhaustion related to cancer or cancer treatment - can severely interfere with activities of daily living, and has even been reported to be a factor in patient requests for…
- Conditions
- Hematopoietic Stem Cell Transplantation, Breast Cancer, Fatigue, Mild Cognitive Impairment
- Trial name
- NCT01873794
- Testing
- Bright white light, Dim red light
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cognitive Remediation, Neuropsychology
Longitudinal Neurocognitive, Psychosocial and Health-related Quality of Life Assessment in Advanced Cancer Survivors Treated With Immunotherapy and the Efficacy of Integrative Neurocognitive Remediation Therapy
Since 2010, the field of immunotherapy has grown substantially, leading to a growing population of long-term cancer survivors treated with immunotherapy.
- Conditions
- Cognitive Remediation, Neuropsychology, Quality of Life, Psycho-Oncology
- Trial name
- CognIT (NCT05667857)
- Testing
- Integrative neurocognitive remediation therapy
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Cancer, Sarcopenia
JUMP Prevalence of Sarcopenia and Chemobrain in Post-cancer Patients
Therapeutic advances in oncology have transformed the prognosis of cancer patients, placing a significant number of them either in a context of recovery or in prolonged remission close to a chronic disease.
- Trial name
- JUMP (NCT05800535)
- Testing
- Study of the adverse effects of long-term oncological treatments, Study of the long-term side effects of oncological treatments on the anxiety-depressive and cognitive state of patients
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer, Neurotoxicity
EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer
RATIONALE: Chemotherapy may cause memory loss, attention loss, and other problems that make it difficult for patients to think clearly. EGb761 may help maintain mental clarity in patients undergoing chemotherapy.
- Trial name
- NCT00046891
- Testing
- Ginkgo Biloba
- Where
- 175 sites in United States
- Volunteers
- 226 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer, Cognitive Dysfunction
eHealth Interventions for Breast Cancer Cognitive Impairment
This study investigates the effectiveness of integrating a cognitive rehabilitation module into a digital psychosocial intervention for recently diagnosed breast cancer patients.
- Trial name
- ICOgnition (NCT06103318)
- Testing
- ICOgnition
- Volunteers
- 176 people
- Sponsor
- Institut Català d'Oncologia
Breast Neoplasms
Telehealth Program to Prevent Cancer and Chemotherapy-related Cognitive Impairment.
The present randomized controlled trial has the main objective to study the effects of a videoconferenced occupational therapy program in preventing cancer and chemotherapy-related cognitive impairment and other health outcomes…
- Trial name
- NCT04783402
- Testing
- e-OTCAT program, Educational handbook and standard care
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Universidad de Granada
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly