Clinical trials: Cancer Related Fatigue
Cancer-related Fatigue
Feasibility and Expansion Trial of Transcutaneous Vagus Nerve Stimulation (tVNS) for Immune-Related Fatigue in Patients Receiving Immune Checkpoint Inhibitors
This study evaluates whether a non-invasive device called transcutaneous vagus nerve stimulation (tVNS) can be safely and feasibly used to help reduce fatigue in patients receiving immunotherapy for cancer.
- Trial name
- NCT07529431
- Testing
- Participants will self-administer transcutaneous vagus nerve stimulation (tVNS) at home using a non-invasive auricular stimulation device for 60 minutes per day over a 6-week period. Participants will
- Volunteers
- 13 people
- Sponsor
- University of Vermont Medical Center
Breast Cancer, Prostate Cancer
Lighting Intervention for Cancer-related Fatigue
Fatigue is a major problem for cancer patients, and one that can persist long after treatment ends. Recent work has demonstrated that light therapy may mitigate or reduce fatigue levels in both cancer patients and cancer…
- Conditions
- Breast Cancer, Prostate Cancer, Hematologic Malignancy, Survivorship
- Trial name
- NCT04827446
- Testing
- Wearable Sensor, Blue-blocking glasses, Clear glasses
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of Michigan Rogel Cancer Center
Cancer-related Fatigue
Clinical Effect of Laser Acupuncture on Improving Cancer-related Fatigue
The aim of this study is to examine the clinical effect of laser acupuncture on improving cancer-related fatigue
- Trial name
- NCT04947969
- Testing
- laser acupuncture
- Volunteers
- 100 people
- Sponsor
- Taichung Tzu Chi Hospital
Fatigue Related to Cancer Treatment, Colon Cancer
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastatic® 300mg Capsule in Reducing Cancer-Tumor in Patients With Metastatic Colorectal Cancer Receiving Standard Chemotherapy.
The goal of this clinical trial is to evaluate whether Nuvastatic 300 capsule can reduce cancer-related fatigue in adult patients with colon cancer undergoing first-line chemotherapy.
- Trial name
- NuvastaticTM (NCT07669454)
- Testing
- Nuvastatic 300
- Where
- 6 sites in India
- Volunteers
- 250 people
- Sponsor
- Natureceuticals Sdn Bhd
Cancer, Fatigue
Cancer Related Fatigue in Patients Receiving Chemotherapy
The purpose of this study is to examine the degree of fatigue in patients receiving chemotherapy. Special interest goes out to the course of fatigue throughout five treatments and the actions taken by patients to reduce this…
- Trial name
- NCT00261534
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- Medical Center Alkmaar
Cancer-related Fatigue, Survival
PG2 Concurrent With Chemoradiation for Locally Advanced Esophageal Cancer
The primary objective of this study is to evaluate the efficacy of PG2 concurrent with concurrent chemoradiation therapy (CCRT) for relieving fatigue among locally advanced esophageal cancer patients who are under preoperative…
- Conditions
- Cancer-related Fatigue, Survival, Tumor, Esophageal
- Trial name
- NCT03611712
- Testing
- Astragalus Polysaccharides 500 mg
- Where
- 4 sites in Taiwan
- Volunteers
- 48 people
- Sponsor
- PhytoHealth Corporation
Fatigue
The Use of an Open Label Placebo to Treat Cancer Related Fatigue in Cancer Survivors
The purpose of this randomized-controlled, crossover pilot trial is to evaluate the feasibility, acceptability and effects of a non-deceptive (open-label) administration of placebo pills for treating cancer related fatigue (CRF).
- Trial name
- OLPI (NCT02522988)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Alabama at Birmingham
Cancer Diagnosis, Moderate or Severe Score of Cancer-related Fatigue (CRF)
STEpwise Research Program to Promote INGeniouS ONline Supportive Solutions in the Relief of Cancer-related Fatigue
Decentralized, randomized hybrid type 2 (effectiveness/implementation) controlled trial comparing the effectiveness of three different digital aid modalities programs in reducing the perceived burden of CRF in cancer patients…
- Trial name
- STEPPING-STONe (NCT06505590)
- Testing
- Educational content, Educational material plus self-management program - self-administered version, Educational material plus self-management program - guided version with mental health professional
- Where
- France
- Volunteers
- 372 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Acute Leukemia
Patient Activation, Counseling and Exercise - Acute Leukemia (PACE-AL)
The purpose of this study is to test a new preventive and restorative intervention for patients with acute leukaemia undergoing consolidation chemotherapy, to measure and delineate the patients' treatment related symptom burden…
- Trial name
- PACE-AL (NCT01404520)
- Testing
- Exercise based multimodal intervention
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Universitetshospitalernes Center for Sygepleje
Fatigue Symptom, Lymphoma Non-Hodgkin
Study of the Association Between Fatigue Experienced by Patients and the Specific Side Effects of CART Cells, During the First Month After Administration for Non-Hodgkin's Lymphoma
The incidence of cancer in 2023 is estimated at 433136 cases, according to INCa. Haemopathies account for 12% of these new cases of cancer cases of cancer, and around two-thirds are lymphoid haemopathies, in particular lymphomas.
- Conditions
- Fatigue Symptom, Lymphoma Non-Hodgkin, Chimeric Antigen Receptor T-cell Therapy, Adverse Events
- Trial name
- CAR-TIGUE (NCT06890091)
- Testing
- Fatigue assessment
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Digestive Tract
Shenqi Fuzheng Injection for the Treatment of Cancer-related Fatigue in Chemo Patients With Digestive Tract .
The efficacy and safety of cancer patients in patients with gastrointestinal cancer (chemotherapy) in patients with gastrointestinal tumor (chemotherapy) were prospectively, randomized blind, multicenter clinical trials.
- Trial name
- NCT03455205
- Testing
- shenqifuzheng, 0.9%sodium chloride
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Prostate Carcinoma
Methylphenidate and Exercise in Reducing Cancer-Related Fatigue in Patients With Prostate Cancer
This phase II/III trial studies how well methylphenidate and exercise work in reducing cancer-related fatigue in patients with prostate cancer.
- Trial name
- NCT03772834
- Testing
- Exercise Intervention, Methylphenidate, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Cancer-related Fatigue
Behavioral Activation for Cancer-Related Fatigue After Breast Cancer Surgery
Cancer-related fatigue is common after breast cancer surgery and may persist during adjuvant treatment and early survivorship. This randomized controlled trial evaluated whether an 8-week graded behavioral activation intervention…
- Trial name
- NCT07799909
- Testing
- Behavioral Activation, Care as Usual
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Huaidong Cheng
Lung Cancer, Advanced Cancer
Acceptance and Commitment Therapy on Fatigue Interference in Patients With Advanced Lung Cancer and Caregiver Burden (ACT)
Lung cancer is a malignant tumour that has transformed from a single cancer disease into one of the most striking global health problems.
- Conditions
- Lung Cancer, Advanced Cancer, Caregiver Burden
- Trial name
- NCT05885984
- Testing
- Acceptance and Commitment Therapy (ACT) plus health education, Health education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Chemotherapy-Related Nausea and/or Vomiting, Early Stage Breast Carcinoma
Evaluating the Association Among Changes in Gut Microbiome, Fatigue, and Chemotherapy-Induced Nausea in Early Stage Breast Cancer
This pilot study seeks to understand how changes in the bacteria composition (microbiome) of the gut may be associated with the occurrence of fatigue and chemotherapy-induced nausea (CIN) in women undergoing chemotherapy for…
- Conditions
- Chemotherapy-Related Nausea and/or Vomiting, Early Stage Breast Carcinoma, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT05417867
- Testing
- Biospecimen Collection, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Mayo Clinic
Cancer, Fatigue
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy
Background: Fatigue is a very common early and late side effect of cancer treatment, including radiation therapy. The cause of fatigue is poorly understood, making it hard to diagnose and treat.
- Trial name
- NCT01143467
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- National Institute of Nursing Research (NINR)
Breast Cancer
Experience of the Patient Treated With Trastuzumab (Herceptin ®) as Adjuvant for Breast Cancer
Many studies have been devoted to the quality of life of patients during adjuvant chemotherapy for breast cancer by highlighting fatigue, psychological distress and impact on the immediate environment (spouse, children) during…
- Trial name
- HER-ception (NCT01400438)
- Testing
- questionnaires
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Francois Baclesse
NSCLC, Fatigue
Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia
The purpose of this study is to asses the safety and efficacy of ALD518 in patients with Non-Small Cell Lung Cancer-Related Fatigue and cachexia (weight-loss).
- Conditions
- NSCLC, Fatigue, Cachexia
- Trial name
- NCT00866970
- Testing
- ALD518, Infusion of 0.9% Saline without ALD518
- Where
- 43 sites in Australia, Canada and 7 more
- Volunteers
- 124 people
- Sponsor
- CSL Behring
Cancer-related Fatigue
The Efficacy of Health Navigation® for Cancer-Related Fatigue in Cancer Survivors
The objective of this study is 1. to develop a web-based, tailored program for Cancer-related fatigue in cancer survivors, which is comprehensive and evidence-based, 2.
- Trial name
- NCT01228773
- Testing
- Tailored web-based care program (Health Navigation®)
- Where
- South Korea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Breast Cancer, Fatigue
Using Pranayama and Deep Breathing Exercises to Reduce Cancer-Related Fatigue and Insomnia During Radiotherapy
The study aims to evaluate the effectiveness of pranayama and deep breathing exercise in reducing fatigue and insomnia in patients receiving radiotherapy due to breast cancer.
- Conditions
- Breast Cancer, Fatigue, Insomnia
- Trial name
- NCT04441827
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University