Clinical trials: Cancer Screening
CRC, Advanced Neoplasia
Prospective Clinical Validation of a Novel Multitarget FIT in CRC Screening
The primary goal of the population-based colorectal (CRC) screening is early detection and interception of CRC and its precursors to decrease CRC-related morbidity and mortality.
- Trial name
- mtFIT (NCT05314309)
- Testing
- Comparison of two tests (FIT and mtFIT) in the same bowel movement
- Where
- Netherlands
- Volunteers
- 14,712 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Human Papilloma Virus, Cervical Dysplasia
Educational Video's Impact on Knowledge Regarding Cervical Cancer Screening
The researchers will be conducting a prospective randomized trial where the researchers will be introducing an educational video to see whether there is an increase in knowledge scores surrounding cervical cancer, cervical cancer…
- Trial name
- NCT05756192
- Testing
- Educational video
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- George Washington University
Women's Health: Cervical Neoplasm
Mobile Outreach Screening of High-Risk Human Papillomavirus Infection in Women with Limited Access to Health Services in Seine-Saint-Denis (greater Paris Area, France)
The study is a prospective cervical cancer screening intervention in the nonclinical setting of a mobile testing unit in a vehicle, using point-of-care HPV PCR tests with self-collected vaginal swabs.
- Trial name
- PAPMOBILE (NCT06656611)
- Testing
- HPV self sampling
- Where
- France
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Health Behavior, Breast Cancer Screening
Improving Breast Cancer Screening Uptake Through Tailored Reminder Letters
The goal of this trial is to learn whether a culturally and linguistically tailored reminder letter can increase participation in the Flemish Breast Cancer Screening Program among women who previously did not attend screening.
- Conditions
- Health Behavior, Breast Cancer Screening, Mammography
- Trial name
- ENTER (NCT07472036)
- Testing
- Tailored reminder letter
- Where
- 2 sites in Belgium
- Volunteers
- 7,947 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Renal Cell Carcinoma
Yorkshire Kidney Screening Trial
Kidney cancer is the 8th most common cancer in Yorkshire. It has a poor survival rate, with only 6 out of 10 patients diagnosed with kidney cancer still alive after 5 years.
- Trial name
- YKST (NCT05005195)
- Testing
- Low dose abdominal computed tomography scan
- Where
- United Kingdom
- Volunteers
- 5,850 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Preventive Health Services
Coordinated Endoscopic Colorectal Cancer Screening
The investigators aim to use a randomized design to test the effects of 1) tailored physician recommendations, relative to non-specific recommendations, and 2) coordinated physician office management systems on patient adherence…
- Trial name
- NCT00327457
- Testing
- Help with physician office and patient management, Tailored physician recommendation letter
- Where
- United States
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Carcinoma
A Patient Reminder and Self-Referral Via Online Patient Portals and Text Messaging to Improve Adherence to Breast Cancer Screening
This clinical trial evaluates the patient reminders and self-referrals via online patient portals and text messaging (PReVenT) intervention for improving adherence to breast cancer screening.
- Trial name
- PReVenT (NCT05526872)
- Testing
- Best Practice, Health Education, Interview
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Emory University
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Cancer
Assessment of the Implementation of an Investigational Multi-Cancer Early Detection Test Into Clinical Practice
PATHFINDER is a prospective, multi-center study in which approximately 6,200 participants will be enrolled. An investigational multi-cancer early detection test, developed by GRAIL, will be ordered by and results returned to a…
- Trial name
- NCT04241796
- Testing
- Multi-Cancer Early Detection Test
- Where
- 11 sites in United States
- Volunteers
- 6,662 people, healthy volunteers welcome
- Sponsor
- GRAIL, Inc.
Breast Cancer
Novel Thermal Imaging Technique for Breast Screening
This trial is to study a new breast imaging tool called Thermalytix™. ThermalytixTM is a new radiation-free, automated breast cancer screening technique that uses Artificial Intelligence (AI) over thermal images.
- Trial name
- NCT05650086
- Testing
- Thermalytix
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Lung Cancer, Cardiovascular Disease (CVD)
Optimised Lung Cancer Screening to Prevent Cardiovascular and Pulmonary Diseases Coupled With Primary Prevention
This project aims to implement a health prevention program for smokers or former smokers including early detection of lung cancer, cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD).
- Conditions
- Lung Cancer, Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SMAC-1 (NCT04315766)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Colon Cancer
Impact of a Mailed Educational Reminder on Fecal Occult Blood Testing (FOBT): A Randomized Controlled Trial
The purpose of our randomized controlled trial is to determine whether mailed educational reminders would increase fecal occult blood test (FOBT) card return rates and, therefore, improve patient compliance with colonrectal…
- Trial name
- NCT00534053
- Testing
- Mailed Educational Reminder
- Where
- United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Myasthenia Gravis, Neuromuscular Disease
Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment
This study expands and validates the pilot study NCT06381284. It is a fully remote, site-less, prospective, observational study enrolling adults in the United States (excluding U.S.
- Conditions
- Myasthenia Gravis, Neuromuscular Disease, Neuromuscular Manifestations
- Trial name
- NCT06866483
- Testing
- Social media recruitment, Self-Assessment, Follow-up
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ZS Associates
Colorectal Cancer
Low Literacy Intervention for Colorectal Cancer Screening
Of 17 performance measures of hospital quality regularly reported for the Veterans Administration (VA) health care system, rates of colorectal cancer screening are the lowest.
- Trial name
- NCT00012922
- Testing
- Low Literacy Intervention for Colorectal Cancer Screening
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Colorectal Cancer
The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy
Evaluation of the histologically proven adenoma and carcinoma detection rate in patients undergoing a full colonoscopy with and without mucosal contrast enhancement, obtained with 200 mg of Methylene Blue MMX® tablets.
- Trial name
- NCT01694966
- Testing
- Methylene Blue MMX®
- Where
- 19 sites in United States, Belgium and 6 more
- Volunteers
- 1,249 people, healthy volunteers welcome
- Sponsor
- Cosmo Technologies Ltd
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Improving Prison Health Equity Through Cancer Literacy and Screening Awareness in Florida
This study evaluates cancer screening awareness, personal and family cancer history, and barriers to screening among incarcerated women at Gadsden Correctional Facility.
- Trial name
- NCT07215039
- Testing
- Survey
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lung Cancer Screening
Lung Cancer Screening by Low Dose CT Scan in a French Department (DEP KP80)
Lung cancer is the leading cause of cancer death worldwide. The aims of this study were to assess the feasibility and effectiveness of a lung cancer screening pilot program with LD CT scan in a French department (Somme).
- Trial name
- NCT03853967
- Testing
- Low dose CT scan
- Where
- France
- Volunteers
- 1,307 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier d'Abbeville
Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer
Validation of a Nutrition Screening Tool
The objective of this study is to evaluate the sensitivity and specificity of two nutrition screening tools to identify inpatients with malnutrition or at risk of malnutrition.
- Conditions
- Adenocarcinoma of the Gastroesophageal Junction, Cervical Cancer, Endometrial Cancer, Esophageal Cancer
- Trial name
- NCT01851928
- Where
- United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Colorectal Cancer
A Multi Center Study Comparing the Efficacy of CAD EYE and the Standard of Care (White Light )
This study is to assess the sensitivity and added benefits of CADEYE compared to standard care (white-light) in detecting colon polyps in patients undergoing colonoscopy.
- Trial name
- NCT05523271
- Testing
- CAD EYE (Computer Aided Diagnosis ----?
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Prostate Cancer
Prostate Cancer Awareness and Initiative for Screening in the European Union
PRAISE-U was initiated on the 1st of April 2023 and is set to last for three years. This collaborative effort involves 25 institutions across 12 countries, all driven by a shared objective: to rationalize prostate cancer…
- Trial name
- PRAISE-U (NCT06424275)
- Testing
- Risk-based screening algorithm
- Where
- 5 sites in Ireland, Lithuania and 2 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- European Association of Urology Research Foundation