Clinical trials: Cancer Support
Myelodysplastic Syndrome (MDS)
Study of Vidaza (Azacitidine) Versus Support Treatment in Patients With Low Risk Myelodysplastic Syndrome (Low and Intermediate-1 IPSS) Without the 5q Deletion and Transfusion Dependent Anaemia
Primary Outcome Measures: To evaluate the efficacy of treatment with Azacitidine in patients with transfusion-dependent, low risk International Prognostic Scoring System (IPSS) 0 int-1, Myelodysplastic Syndrome (MDS) without…
- Trial name
- ABRAZA (NCT01338337)
- Testing
- Azacitidine
- Where
- 9 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Asociación Andaluza de Hematología y Hemoterapia
Cancer
Navigated Early Survivorship Transition in Patients With Newly Diagnosed Cancer and Their Caregivers
This pilot clinical trial studies the Navigated Early Survivorship Transition (NEST) intervention in improving survivorship care planning in patients with newly diagnosed cancer and their caregivers.
- Trial name
- NEST (NCT02440737)
- Testing
- Educational Intervention, Follow-Up Care, Psychosocial Assessment and Care
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Advanced Lung Cancer
Exercise, Nutrition, and Palliative Care in Advanced Lung Cancer (ENPAL)
Background: Evidence supports exercise and nutrition as beneficial for enhancing QOL in earlier stages of lung cancer; however, there is minimal research of either intervention - and none with combined interventions - in advanced…
- Trial name
- ENPAL (NCT04575831)
- Testing
- Exercise, Nutrition, and Palliative Symptom Management
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Cancer
Behavioral Coaching Intervention (Laguna Health) for Patients With Cancer
The overall goal of this study is to examine the feasibility, acceptability, and preliminary efficacy of using a behavioral coaching intervention (Laguna Health) for optimizing post-hospital discharge care in patients with…
- Trial name
- LAGUNA (NCT06004141)
- Testing
- Laguna Health
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Massachusetts General Hospital
Non-Cancer Pain,Musculoskeletal Pain,Chronic Pain,Acute Pain
Real-World Study of Acupuncture for Pain Control
The goal of this observational study is to evaluate the real-world effectiveness of an acupuncture-first stepped care pathway for pain management in adults aged 18 years and older receiving routine outpatient clinical care for…
- Trial name
- NCT07454083
- Testing
- Acupuncture-First Stepped Care Pathway (Routine Clinical Care)
- Volunteers
- 300 people
- Sponsor
- Qi's Clinic
Gastrointestinal Cancer
EAT-ING: Enhancing Anticancer Treatment Safety Via Immunomodulatory Nutritional Support in Advanced Gastrointestinal Cancers
The use of immunomodulants in patients with GI cancer has been progressively gaining attention in the last years, as a high-calorie-high-protein nutritional blend enriched in immunonutrients has shown efficacy in several studies…
- Trial name
- EAT-ING (NCT07590622)
- Testing
- LH BLU, ONS
- Volunteers
- 88 people
- Sponsor
- IRCCS San Raffaele
Metastatic Breast Cancer
IMaging PAtients for Cancer Drug selecTion - Metastatic Breast Cancer
Current patient work-up, including conventional imaging and pathological assessment of just one single biopsy, might be insufficient to identify metastatic breast cancer patients, who possibly benefit from first-line…
- Trial name
- IMPACT-MBC (NCT01957332)
- Testing
- Molecular imaging
- Where
- 3 sites in Netherlands
- Volunteers
- 217 people
- Sponsor
- University Medical Center Groningen
Testicular Cancer, Testis Cancer
Virtual Testis Cancer Lay Support and Survivorship Aim 2
This study examines how virtual support can enhance well-being and survivorship in men with testicular cancer. Participants in North Carolina will be randomized into two groups: one with access to a virtual support platform and…
- Trial name
- VITALSS (NCT06702592)
- Testing
- Virtual support, Patient educational material
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Distress, Breast Cancer
Couplelinks.ca - An Online Intervention for Couples Affected by Breast Cancer
Women diagnosed with breast cancer (BC) at or before the age of 50 experience more distress and poorer quality of life than women diagnosed later in life.
- Conditions
- Distress, Breast Cancer, Depression, Anxiety
- Trial name
- couplelinks (NCT01089764)
- Testing
- Couplelinks.ca website
- Where
- 5 sites in Canada
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Canadian Breast Cancer Research Alliance
No Metastatic Breast Cancer
Personalized Preventive Support for Cognitive Impairment in Non-Metastatic Breast Cancer (EFACog)
EFACog is a single-center prospective cohort feasibility study conducted on a single group of patients to study the feasibility of a personalized support program by a nurse conducted over 9 months, using face-to-face and…
- Trial name
- EFACog (NCT05538000)
- Testing
- Face to face and telephonic interviews
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut de Cancérologie de Lorraine
Gynecologic Cancer, Remission
Impact of a Multidisciplinary Assessment in Day Hospitalization Versus Standard Care on the Deployment of Supportive Oncology Care Recommended by the Personalized Post-cancer Plan in Patients at the End of Initial Treatment for Gynecological Ovarian and Endometrial Cancer Endometrial Cancer
This project proposes a structuring of supportive oncology care for the recovery phase after gynecological cancer (ovarian/trope/peritoneum or endometrium).
- Trial name
- AFTERGYN2 (NCT06553612)
- Testing
- Multidisciplinary assessment, Standard assesment, Observational cohort
- Where
- 13 sites in France
- Volunteers
- 268 people
- Sponsor
- Centre Francois Baclesse
Cardiopulmonary Arrest, Pediatric ALL
Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
This study will be a prospective, single-center, randomized controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary pediatric physicians and nurses.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- InterFACE (NCT04464603)
- Testing
- InterFACE (mHealth tool), Conventional methods
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Cancer
High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill…
- Trial name
- NCT00002854
- Testing
- filgrastim, carboplatin, cisplatin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- City of Hope Medical Center
Heart Failure, Cardiotoxicity
The Harmonized Interventions to Maintain Health Via Appropriate Risk Factor Modification and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Pilot Study
Cardiovascular disease (CVD) is a major contributor to morbidity and mortality in pediatric, adolescent and young adult (AYA) cancer survivors (hereafter referred to as PAYA-CS).
- Conditions
- Heart Failure, Cardiotoxicity, Cancer
- Trial name
- HIMALAYAS-P (NCT04598646)
- Testing
- Cardio-oncology Rehabilitation (CORE), Support
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Nursing Students, Education
Flipped Learning in Nursing Education
This study aims to examine the effects of cancer screening training, conducted using a ChatGPT-based flipped learning model, on knowledge, learning motivation, and class participation.
- Conditions
- Nursing Students, Education, Flipped Education Model
- Trial name
- NCT07349862
- Testing
- ChatGPT-Based Flıpped Learning Model, Traditional Flıpped Learning Model
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Polycystic Ovarian Syndrome (PCOS)
Exercise Programs in Women With PCOS
This study aims to investigate the effectiveness of a digital rehabilitation-supported combined exercise program in women with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT07509762
- Testing
- Face-to-face exercise, Digital rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Biruni University
Non Small Cell Lung Cancer
Induction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim
Patients enrolled on this study will have been diagnosed with non-small cell lung cancer which cannot be removed by an operation.
- Trial name
- NCT00280787
- Testing
- Paclitaxel, Carboplatin, CPT-11
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Digestive System Neoplasms, Thoracic Neoplasms
Effectiveness of an Educational Intervention Aimed at Increasing the Emotional Competencies of Patients Under Surveillance After Antineoplastic Treatment of Oesogastric or Bronchopulmonary Cancer
Emotional skills are the ability to use emotions cleverly in daily life. Good emotional skills are associated with better mental and physical health in healthy and clinical populations.
- Trial name
- EmoVie_K2 (NCT04556344)
- Testing
- Emotional skills, Short free talk and relaxation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Lille
Multiple Myeloma
Bortezomib and High-dose Melphalan at Myeloma Relapse
The prognosis after retreating with high-dose melphalan with stem cell support after first relapse after high-dose treatment is dependent on the time to first relapse. Bortezomib can increase chemosensitivity of e.g. melphalan.
- Trial name
- NCT00508209
- Testing
- bortezomib
- Where
- 9 sites in Denmark, Norway and 1 more
- Volunteers
- 50 people
- Sponsor
- Nordic Myeloma Study Group
Covid19, Oncology
An Integrated Digital PROM-platform for Cancer Patients During the COVID-19 Pandemic
During the COVID-19 pandemic, patients with cancer are subject to multiple risks (e.g. frequent hospital visits, increased infection risk, more severe clinical course, discontinued cancer treatment etc.).
- Conditions
- Covid19, Oncology, PROMs, Chemotherapeutic Toxicity
- Trial name
- COVID-ONCO (NCT04816656)
- Testing
- ePROMs assessment
- Where
- 2 sites in Belgium
- Volunteers
- 43 people
- Sponsor
- Jessa Hospital