Clinical trials: Cancer of Colon
Colorectal Neoplasms, Urologic Neoplasms
Transvaginal Versus Transabdominal Extraction of Laparoscopically-excised Specimen
The aim of this study is to evaluate the outcomes of transvaginal natural orifice specimen extraction (NOSE) in patients who are planning multiport laparoscopic surgery for resection of solid organs including kidney, liver…
- Conditions
- Colorectal Neoplasms, Urologic Neoplasms, Gastrointestinal Neoplasms, Neoplasms by Site
- Trial name
- STTELS (NCT05113134)
- Testing
- Transvaginal natural orifice specimen extraction (NOSE)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Adenoma
The MORDIS Study Clinical Investigational Plan
To demonstrate the use of WavSTAT4 system during colonoscopy in identifying diminutive colorectal lesions (e.g. hyperplastic polyps) that can be resected and discarded (or even left in-situ) without adverse clinical impact.
- Trial name
- MORDIS (NCT01980134)
- Where
- 6 sites in Czechia, Denmark and 3 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SpectraScience
Colonic Cancer
A Follow-up Colonoscopy Examination in Patients Who Had Previously Undergone Screening Colonoscopy
To determine the prevalence of colonic neoplasm in patients who had previously undergone screening colonoscopy To determine the optimal time interval for re-screening in average risk individuals To determine potential baseline…
- Trial name
- NCT00280332
- Testing
- colonoscopy
- Where
- China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colon Adenoma, Colorectal Cancer
Clinical Efficacy Evaluation of a Computer-aided Colonoscopy as Compared With the Standard Colonoscopy.
Colonoscopy is clinically used as the gold standard for detection of colorectal cancer (CRC) and removal of adenomatous polyps of the colon and rectum.
- Trial name
- NCT05240625
- Testing
- "aetherAI" Computer-aided Polyp Detection (CADe) Systems for Colonoscopy, Standard colonoscopy
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer
The Roles of Exosomal Circ-LRBA and 451/CRTC2 Signaling Axis in Colorectal Cancer
Colorectal cancer (CRC) is one of the most common malignant tumors in the world. Most of the patients with colorectal cancer were diagnosed in poor stage.
- Trial name
- NCT05579353
- Testing
- nothing
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Jingbo Chen
Colon Cancer, Rectal Cancer
Prevention of Colorectal Cancer Through Multiomics Blood Testing
The PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a…
- Conditions
- Colon Cancer, Rectal Cancer, Colon Neoplasm, Colon Diseases
- Trial name
- PREEMPT CRC (NCT04369053)
- Testing
- Freenome test
- Where
- 148 sites in United States, Canada
- Volunteers
- 48,995 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Diabetes Risk, CVD Risk
Effectiveness of a Self-health Assessment Mobile Application in Young-to-midlife Adults in Hong Kong
This project aims to compare the effectiveness of Wellnuts, an evidence-based, algorithm-driven self-health assessment mobile application, in empowering asymptomatic young-to-midlife adults in Hong Kong, promoting health…
- Conditions
- Diabetes Risk, CVD Risk, Colorectal Cancer, Lung Cancer
- Trial name
- NCT07720245
- Testing
- Wellnuts app intervention, Web-based health resources
- Where
- Hong Kong
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colon Cancer
Role of the Spouse/Partner of Persons Treated With Chemotherapy for Colon Cancer
Altered quality of life in patients with stage III or IV colon cancer is well known. At their sides, their spouse/partner must also cope with the suffering caused by the disease and the upheavals that it engenders, with the…
- Trial name
- APPACH (NCT02873845)
- Testing
- Preliminary validation of the COBQoL questionnaire
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Colorectal Cancer, Colon Cancer
Pilot Study of Colon Cancer Screening Tests
Colon cancer is the second leading cause of cancer death in North America. These deaths are preventable with proper screening. Fecal occult blood testing, virtual colonoscopy, and standard (optical) colonoscopy are all options…
- Conditions
- Colorectal Cancer, Colon Cancer, Adenomatous Polyps
- Trial name
- NCT00865527
- Testing
- Fecal occult blood test, Virtual colonoscopy, Optical colonoscopy
- Where
- Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Colorectal Cancer
Trial of a Multilevel Intervention to Increase Colorectal Cancer Screening
This study will assess the effectiveness of a culturally-responsive intervention to increase colorectal cancer (CRC) screening among Latino immigrants in a primary care clinic setting of a large municipal Hospital in New York…
- Trial name
- NCT00836303
- Testing
- Colorecatal Cancer Screening Activation
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Colon Cancer Prevention
Effect of Exercise on Biomarkers of Colon Cancer Risk
There is strong observational epidemiologic evidence that physical activity is inversely associated with risk of colon cancer occurrence in both men and women.
- Trial name
- APPEAL (NCT00668161)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Cancer, Colorectal Neoplasms
Early Onset Colorectal Cancer Detection
Colorectal cancer (CRC) once predominantly affected older individuals, but in recent years has witnessed a progressive increase in incidence among young adults.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, Colorectal Cancer Stage I
- Trial name
- ENCODE (NCT06342401)
- Testing
- ENCODE
- Where
- 13 sites in United States, Italy and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Cancer, Colorectal Cancer Screening
Colorectal Cancer Screening Intervention Trial
Colorectal cancer is the second deadliest among cancers and disproportionately affects African Americans. The Colorectal Cancer Screening Intervention Trial(CCSIT) project has as its goal to test three interventions designed to…
- Trial name
- NCT00265720
- Testing
- Control, Reduced out of pocket expense, one on one education
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Colorectal Cancer Screening, Colon Polyps and Adenomas
Artificial Intelligence (AI) Technology May Help Patients to Understand Bowel Preparation Better Before They go for Colonoscopy.This Study Attempts to Leverage AI Chatbot in Counselling Patients to Improve Bowel Cleanliness, Reduce Anxiety as Well as Increase Procedural Satisfaction
Traditional pre-colonoscopy counselling requires significant time from healthcare workers to explain procedures, limiting efficiency and patient turnover.
- Conditions
- Colorectal Cancer Screening, Colon Polyps and Adenomas, Bowel Preparation Quality, Artificial Intelligence (AI)
- Trial name
- NCT06905782
- Testing
- AI chatbot study arm, Traditional counselling study arm
- Where
- Malaysia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
This randomized clinical trial studies the Family Caregiver Palliative Care Intervention in supporting caregivers of patients with stage II-IV gastrointestinal, gynecologic, urologic and lung cancers.
- Conditions
- Healthy Subject, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT01846520
- Testing
- educational intervention, telephone-based intervention, quality-of-life assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colon Cancer Stage IIb, Rectum Cancer, Adenocarcinoma
Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers
The main reason of cancer-related mortality is the spread of cancer cells to distant sites (micrometastases). However, only a few small groups of tumor cells can metastasize by acquiring mechanism to decrease the immune response.
- Conditions
- Colon Cancer Stage IIb, Rectum Cancer, Adenocarcinoma, Colon Cancer Stage IIIa, Colon Cancer Stage IIIc
- Trial name
- BMACR (NCT02979470)
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AC Camargo Cancer Center
Colorectal Cancer, Precancerous Condition
Biological, Genetic, and Lifestyle Risk Factors for Developing Colorectal Adenomas or Polyps in Participants Undergoing Colonoscopy
RATIONALE: Collecting and storing samples of tissue, blood, and other body fluids to test in the laboratory and gathering information about health and lifestyle from participants may help doctors learn more about cancer risk…
- Trial name
- NCT00625066
- Testing
- biologic sample preservation procedure, cytology specimen collection procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,108 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Colon Cancer
Linked Color Imaging/Magnifying Blue Laser Imaging vs. White Light for Adenomas and Serrated Lesions in Proximal Colon
Linked color imaging (LCI) and magnifying blue laser imaging (BLI) are two new imaging systems used in endoscopy which are recently developed. BLI was developed to compensate for the limitations of NBI.
- Trial name
- NCT02724397
- Testing
- LCI/BLI then white endoscopy, White endoscopy and then LCI/BLI
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Colorectal Adenoma, Colorectal Polyp
Validation of the Global Polypectomy Assessment Tool (GPAT)
Colorectal polypectomy is offten incompletely performed with high variability between endoscopists, resulting in interval cancer or repeated procedures.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- GPAT (NCT05877456)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colon Cancer Screening
A Study of Using Social Networks to Encourage Three Peers to Complete Screening for Colorectal Cancer
The Black community has higher rates of colorectal cancer and lower rates of colorectal cancer screenings than whites. Getting screened through FIT testing may help catch colorectal cancer earlier, when it is easier to treat.
- Trial name
- NCT05793593
- Testing
- FITx3 intervention and CRC education, Colorectal Cancer (CRC) education alone
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center