Clinical trials: Cancer of Prostate
Cancer Survivor, Depression
Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
RATIONALE: Telephone counseling after radical prostatectomy may help African American prostate cancer survivors and their intimate partners cope with the problems and challenges of surgery, and may reduce distress and improve…
- Conditions
- Cancer Survivor, Depression, Gastrointestinal Complications, Male Erectile Disorder
- Trial name
- NCT00869739
- Testing
- telephone-based intervention, educational intervention, partner-assisted coping skills training
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Prostate Cancer
Predictors of Mental Health in Men With Prostate Cancer Undergoing a Patient Empowerment Program
Each year over 20,000 men are diagnosed with prostate cancer in Canada with the majority undergoing some form of treatment option.
- Trial name
- PC-PEP (NCT04895839)
- Testing
- Patient Empowerment Program
- Where
- 16 sites in Belgium, Canada and 3 more
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Gabriela Ilie
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Adenocarcinoma)
Investigation of the Diagnostic Role of miRNAs in PCa and BPH
Prostate cancer(PCa) is the second most common cause of cancer-related death in men after lung cancer. Diagnostic methods such as measurement of serum Prostate-specific antigen (PSA) levels used in the clinic still cannot…
- Trial name
- NCT06726070
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Prostate Carcinoma
Prostate Specific Antigen Levels of Individuals Living in Rural Areas
It was planned in cross-sectional design in order to determine the specific prostate antigen level and some characteristics and the relationship evaluations and prostate specific antigen formation in individuals living in rural…
- Trial name
- NCT06900348
- Testing
- PSA-Activated PSA-PAH1
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Prostate Cancer, PET/CT
Head-to-head Comparison of [18F]F-PSMA-N5 With [68Ga]Ga-PSMA-11 PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [18F]F-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT06462508
- Testing
- [18F]F-PSMA-N5, [68Ga]Ga-PSMA-11
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Carcinoma Prostate
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of investigation for prostate cancer in current urology practice.
- Trial name
- NCT01939743
- Testing
- Diclofenac suppository plus lidocaine gel, Lidocaine gel only
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Prostate Carcinoma
Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study
This study investigates ways to detect prostate cancer earlier in people at genetic risk for disease that forms, grows, or spreads quickly (aggressive).
- Trial name
- NCT04472338
- Testing
- Biospecimen Collection, Laboratory Biomarker Analysis, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Washington
Prostate Cancer, Sexual Dysfunctions, Psychological
Innovations in the Treatment of Sexual Health Post Prostate Cancer Treatment: Comparing Mindfulness vs. CBT
Up to 90% of men experience sexual difficulties after receiving treatment for prostate cancer (PC), which can negatively affect their intimate relationships and overall quality of life.
- Conditions
- Prostate Cancer, Sexual Dysfunctions, Psychological, Sexual Dysfunction, Physiological, Sexual Dysfunction Male
- Trial name
- INTROSPPECT (NCT03365518)
- Testing
- Cognitive Behavioural Therapy (CBT), Mindfulness-Based Therapy
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prostate Cancer
The ProCaRis Study: Prostate Cancer Risk Assessment in General Practice
The preferred method for early detection of prostate cancer (PCa) in older men with family history is the Prostate Specific Antigen test (PSA test), although the method is imprecise.
- Trial name
- ProCaRis (NCT01739062)
- Testing
- Genetic risk assessment
- Where
- Denmark
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Metastatic Castration Resistant Prostate Cancer
A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics
This is a phase I study evaluating HC-1119 single-dose pharmacokinetics and effect of food on its pharmacokinetics in healthy Chinese adults.
- Trial name
- NCT03776968
- Testing
- HC1119
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hinova Pharmaceuticals Inc.
Prostate Cancer XXX, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY
Effect of Lidocaine Gel and Cold Lidocaine Gel on Pain in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal ultrasound-guided prostate biopsy (TRUSG-PBx) is considered the current gold standard method in the diagnosis of prostate cancer.
- Trial name
- NCT06429046
- Testing
- LIDOCAINE GEL, COLD LIDOCAINE GEL
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Prostate Cancer, Cancer of the Prostate
Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System
The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care: Defined referral thresholds within the…
- Trial name
- NCT07109427
- Testing
- Annual PSA Health Maintenance Reminder
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Problem Solving Therapy for Prostate Cancer Spousal Caregivers
Problem-solving therapy programs have been shown to be effective among parents of children diagnosed with cancer. Efforts have been made to apply this same strategy to spouses/significant others of men diagnosed with prostate…
- Trial name
- NCT02085096
- Testing
- Problem-Solving Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Decision Support Techniques
Decision Navigation for Advanced Prostate Cancer Treatment Options Using mHealth
Prostate cancer is a commonly diagnosed cancer, and is the second leading cause of cancer deaths among men in the U.S. The subgroup of men with advanced prostate cancer is particularly vulnerable to difficult choices for…
- Trial name
- NCT03327103
- Testing
- CHAMPION
- Where
- 3 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Colon Cancer
Proteomic Analysis of Patients Undergoing Bariatric Surgery
The expression of proteins in the blood of obese individuals is different from the expression of proteins in healthy individuals, and is also different in individuals after bariatric surgery.
- Conditions
- Obesity, Colon Cancer, Thyroid Cancer, Esophageal Cancer
- Trial name
- NCT06787807
- Testing
- bariatric surgery
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Prostate Cancer, PET/CT
Head-to-head Comparison of [18F]AlF-PSMA-N5 With [18F]F-DCFPyL PET/CT in PCa Diagnosis, Recurrence, and Metastasis
To prospectively evaluate the radiodrug biodistribution of a novel PET imaging agent [18F]AlF-PSMA-N5 in different organs of prostate cancer patients and its diagnostic efficacy in the diagnosis, recurrence and metastasis of…
- Trial name
- NCT06756334
- Testing
- [18F]AlF-PSMA-N5, [18F]F-DCFPyL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Breast Cancer, Lung Cancer (Diagnosis)
Building on Trust: Navigating Preventive Lung, Breast, and Prostate Cancer Screenings at Community Resource Spots
To evaluate a community-based outreach initiative for screening, diagnosis, and treatment of breast, lung, and prostate cancers in underserved adults using the Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM)…
- Conditions
- Breast Cancer, Lung Cancer (Diagnosis), Prostate Cancer
- Trial name
- NCT07231159
- Testing
- referral for definitive diagnosis based on their cancer screening results, Engagement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Prostate Cancer (Adenocarcinoma)
Understanding the Benefits of Dietary Fibre Supplementation in Patients With Prostate Cancer
The digestive tract (large intestine) contains microorganisms that digest complex carbohydrates in food to produce chemical substances which are beneficial to human health.
- Trial name
- EVENTIDE (NCT06661044)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Prostate Neoplasm, Prostate Cancer
Strength, Aging, and Memory in Prostate Cancer
The objective of this study is to compare changes in neurocognitive function across a 12-month period between three groups: (1) men treated with androgen deprivation therapy (ADT) for prostate cancer (PCa); (2) men under active…
- Trial name
- STAMP (NCT04852224)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Prostate Cancer, PSA
PSA Glycomics Assay for Early Detection of Prostate Cancer
The principal aim of this pilot study is to test whether the PSA Glycomics Assay on urine and serum samples can provide insights regarding the disease state of patients with elevated PSA concentrations, as well as to accurately…
- Trial name
- NCT04393376
- Testing
- PSA Glycomics Assay
- Where
- 3 sites in Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Prof.dr. H.P. Beerlage